Vaccines induce multiple immune system mechanisms to protect against severe COVID-19 illness

Globally, breakthrough COVID-19 infections among vaccinated people are increasing, raising concerns about the durability of protection against emerging, highly contagious variants of concern. A study publishing May 5th in the open access journal PLOS Biology, by Galit Alter at Harvard University, Cambridge, U.S. and colleagues, suggests that while vaccine-induced neutralizing antibody responses protect against infection, control of viral replication is mediated by responses that involve T cells and the antibody-binding Fc receptor.
Globally, breakthrough COVID-19 infections among vaccinated people are increasing, raising concerns about the durability of protection against emerging, highly contagious variants of concern. A study publishing May 5th in the open access journal PLOS Biology, by Galit Alter at Harvard University, Cambridge, U.S. and colleagues, suggests that while vaccine-induced neutralizing antibody responses protect against infection, control of viral replication is mediated by responses that involve T cells and the antibody-binding Fc receptor.