Researchers have successfully used a virtual population to replicate a clinical trial that examined kidney damage in Black Americans, according to a new study at the University of Mississippi Medical Center in Jackson. John S. Clemmer, Ph.D., a physiologist and lead author of the study, said his team model used a calcium channel blocker to predict kidney damage. They were also able to simulate stopping the damage by adding drug therapy (angiotensin inhibitor) and reducing salt intake. The simulated treatments also improved virtual patients’ heart sizes. The research will be presented in person at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2022 in Philadelphia.
Virtual population model predicts and stops kidney damage in Black Americans
Researchers have successfully used a virtual population to replicate a clinical trial that examined kidney damage in Black Americans, according to a new study at the University of Mississippi Medical Center in Jackson. John S. Clemmer, Ph.D., a physiologist and lead author of the study, said his team model used a calcium channel blocker to predict kidney damage. They were also able to simulate stopping the damage by adding drug therapy (angiotensin inhibitor) and reducing salt intake. The simulated treatments also improved virtual patients' heart sizes. The research will be presented in person at the American Physiological Society's (APS) annual meeting at Experimental Biology 2022 in Philadelphia.