PHOENIX — More than half of patients with severe asthma changed biologics or discontinued treatment as they and their clinicians explored solutions, according to an abstract presented at the CHEST Annual Meeting.
However, trial-and-error approaches may lead to delays in disease control, higher costs and adverse effects, Isabella Novoa Caicedo, MD, postdoctoral research fellow, division of pulmonary, allergy and critical care medicine, Mayo Clinic, and colleagues wrote.
“There are now several biologics available for severe asthma, but we still do not have a clear roadmap for choosing among

PHOENIX — Patients with status asthmaticus hospitalized during the weekend needed more care and experienced more mortality than those admitted during the rest of the week, according to an abstract presented at the CHEST Annual Meeting.
But this “weekend effect” was due to poorer health upon admission, not deficiencies in staffing or treatment, Anthony Lim, MD, an internal medicine physician at the Brooklyn Hospital Center, and colleagues wrote.
Although the phrase “weekend effect” describes variabilities in staffing and delays in escalating care associated with

PHOENIX — At hospital discharge after COPD exacerbation, patients were often inappropriately prescribed inhaled corticosteroids and not prescribed recommended dual bronchodilation, according to data presented at the CHEST Annual Meeting.
“We need to identify practice patterns, identify knowledge gaps if any, [encourage] more adherence to guidelines and ensure medication compliance with patients,” Chineen Shah, MBBS, pulmonary and critical care medicine fellow, told Healio.
In a retrospective chart review of a tertiary care center, Shah and colleagues assessed 145 patients (mean age, 70 years;

PHOENIX — Responses from ChatGPT-4 and -5 on COPD patient education topics received higher scores from two independent pulmonologists than responses from Gemini and OpenEvidence, according to data presented at the CHEST Annual Meeting.
“AI tools are not interchangeable, and a newer version is not necessarily a better one,” Rachana Phadke, MD, internal medicine resident at Saint Vincent Hospital, told Healio. “Before recommending a chatbot to patients or using one to draft education materials, clinicians should review the output for accuracy, alignment with Global Initiative for Chronic

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