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A new pharmaceutical option with fewer side effects may be on the way for kids with Tourette Syndrome, Ecopipam. Neurologists based at Cincinnati Children’s Hospital Medical Center, OH, USA with colleagues from Cincinnati Hospital and Boston Children’s Hospital, MA, USA, reported this week in JAMA Neurology that the drug not only reduced the frequency of […]

The post Bulletin: New Drug Helps Reduce Tourette Tics With Fewer Side Effects appeared first on Medical News Bulletin.

The FDA has approved an immunotherapy combination therapy for adult patients with Bacillus Calmette-Guérin-naive, high-risk non-muscle invasive bladder cancer.
The combination of durvalumab (Imfinzi, AstraZeneca) plus Bacillus Calmette-Guérin (BCG) is the first of its kind to be approved for this patient population, according to a manufacturer-issued press release.
“It is devastating for patients with high-risk non-muscle invasive bladder cancer to face the common, early and repeated disease recurrences that are the hallmark of this disease, let alone the prospect of progressing to more

KIAWAH ISLAND, S.C. — Severely ill pediatric patients can be particularly vulnerable to conditions that affect the ocular surface, according to a speaker.
“That can be due to factors like facial trauma, altered levels of consciousness, mechanical ventilation, and sedation and neuromuscular blockade. These factors all increase their risk for exposure keratopathy,” Elizabeth Mellencamp, MD, a resident at the Medical University of South Carolina’s Storm Eye Institute, said at Kiawah Eye and Retina.
The reported incidence of exposure keratopathy in intubated pediatric patients is 19% to 41%, she

KIAWAH ISLAND, S.C. — In patients with proliferative diabetic retinopathy, ranibizumab delivered with the Port Delivery System yielded a reduced need for rescue intervention vs. panretinal photocoagulation, according to a presenter.
At Kiawah Eye and Retina, Ford Gordon, MD, highlighted a clinical gap in research for the Port Delivery System (Genentech, PDS) as a treatment for proliferative diabetic retinopathy (PDR): While most previous studies have focused on PDS vs. anti-VEGF treatments for PDR, data guiding clinical decision-making between PDS and panretinal photocoagulation (PRP) is

PHOENIX — The biological superior capsular reconstruction biceps transposition technique — also known as bio-SCR — may provide good functional results and be a cost-effective solution for massive rotator cuff tears, according to results.
“The biceps is readily available most of the time and it is a fantastic tissue that you can incorporate in otherwise difficult rotator cuff tears,” Fortunato G. Padua, MD, an orthopedic sports medicine fellow at Mississippi Sports Medicine and Orthopaedic Center, told Healio. “It is cheap and there is no additional cost. You

CHICAGO — Exposure to police violence included risks for poor neurological and psychiatric outcomes, with greater harm for patients with prior challenges, according to a poster presented at the American Academy of Neurology Annual Meeting.
Additionally, patients with neurological challenges are more likely to encounter police violence, according to the poster.
“Our review seeks to highlight neurological and brain health harms as another tragic consequence of exposure to police violence in the United States,” Altaf Saadi, MD, MSc, associate professor of neurology at Harvard Medical School, told

Editor’s Note: This is part two of a two-part Healio Exclusive series on Lp(a). Part one can be seen here.
Late-phase trials of targeted therapies for elevated lipoprotein(a) are nearing completion, with the first readouts expected later this year.
“All the progress in the last 20 to 30 years has now led to targeted therapies for Lp(a) and that’s what’s driving a lot of the excitement and interest right now. There are finally therapies that are hopefully very close to being available,” Harpreet S. Bhatia, MD, MAS, FACC, FAHA, FASPC, assistant professor of medicine in the division of

ACOG recently issued guidance recommending for the first time that clinicians consider concurrent male sex partner therapy with a combination of topical and oral antimicrobial agents for some women with recurrent bacterial symptomatic vaginosis.
The guidance, which ACOG said is backed by “a growing body of evidence implicating sexual activity as a risk factor,” also recommends shared decision-making for concurrent partner therapy for women who have same-sex partners and those with a first occurrence.
ACOG is among the first medical organizations to formally recommend treating partners of

It is one of dermatologists’ most frustrating scenarios: A young person walks into the clinic with multiple skin cancers, yet the cause is not genetic.
Melanoma, the most dangerous form of skin cancer, mainly affects adults older than 60 years, according to the Stanford Medicine Cancer Institute. That is why Pedram Gerami, MD, a skin cancer researcher and director of the Melanoma Clinic at Northwestern University Feinberg School of Medicine, was perplexed when he began diagnosing multiple incidences of melanoma in women younger than 50 years.
“This finding would be seen most typically in older,

To manage dry eye symptoms in Sjögren’s disease, use preservative-free eye drops and treat meibomian gland dysfunction, according to a paper published in Journal of Clinical Medicine.
“Dryness (sicca) of mucosal surfaces is the hallmark of adult-onset Sjögren’s disease,” Elizabeth J. Price, MD, FRCP, of Great Western Hospital, United Kingdom, and colleagues wrote. “In our experience, clinicians frequently lack confidence in managing the sicca symptoms effectively. Successful management requires an understanding of the condition and personalization of care.”
For a special issue of the journal