Navigating Nutraceuticals: Spermidine

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Wondering what spermidine is and why it’s at the top of the supplement sales stack? Get scientifically sourced, evidence-based information about what it’s for, where it comes from and what it can do for you. Not interested in where spermidine got its name or what its chemical make-up is? No worries! Just skip to the […]

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Reneurx nerve-selective therapy may reduce pain for knee OA

DALLAS — Results showed Reneurx nerve-selective therapy may be safe and effective for pain associated with knee osteoarthritis with better pain reduction and functional outcomes compared with intra-articular corticosteroid injections.
“Nerve-selective therapy allows us to have another avenue for conservative management of an osteoarthritis patient in the knee and, in the future, there may be other sites that are amenable to this, as well,” Yogesh Mittal, MD, partner at The Orthopedic Center in Tulsa, Oklahoma, told Healio about results presented at the American Association of Hip and Knee

Pearls for retinal detachment after globe repair

NEW YORK — When surgeons operate on a retinal detachment after globe repair, it is important to optimize the view during the procedure, according to a speaker.
In a presentation from OSN New York Retina, Richmond Woodward, MD, provided his pearls for this scenario.
In a review of more than 900 eyes that underwent primary globe repair at Massachusetts Eye and Ear over a 10-year period, 29% developed retinal detachment (Stryjewski et al.). Woodward said 27% of those detachments occurred within 24 hours, 47% detached within 1 week and 72% detached within a month. Additionally, patients with

GLP-1 prescriptions for obesity have increased rapidly since introduction of Wegovy pill

Oral semaglutide has seen rapid early uptake since its launch at the beginning of 2026, and overall weight loss drug prescriptions — injectable and oral combined — have increased substantially this year, according to a new study.
GLP-1 receptor agonists have become a popular option for treating obesity and cardiovascular, kidney and metabolic diseases, according to research. However, it was previously only available in an injectable formulation when used to treat weight loss specifically. As Healio previously reported, at the end of 2025, oral semaglutide (Wegovy pill, Novo

TED activity, severity guides treatment options

NEW YORK — Ophthalmologists should know the common signs of thyroid eye disease and assess for activity and severity before deciding on treatment, according to a speaker.
In his presentation at OSN New York, Andrew R. Harrison, MD, said many patients and even doctors are misinformed about thyroid eye disease.
“TED is a common disease, and ophthalmologists should be aware of the signs including lid retraction, proptosis, diplopia and anterior segment inflammation,” he told Healio. “It's important to refer patients early to a TED specialist so they can get treated appropriately.”
Activity is

FDA approves Rybrevant Faspro for metastatic head, neck cancer

The FDA granted accelerated approval for amivantamab and hyaluronidase-lpuj for recurrent or metastatic head and neck cancer based on findings showing twice the response rate of previously approved therapies, Johnson & Johnson announced.
Subcutaneous amivantamab and hyaluronidase-lpuj (Rybrevant Faspro; Janssen, Johnson & Johnson) achieved a 42% objective response rate and 15% complete response rate in the phase 1b/2 OrigAMI-4 trial, Healio previously reported.
The approval does not include patients diagnosed with HPV-associated oropharyngeal squamous cell carcinoma.
“For people living

Cataract surgery protocol could help patients with diabetes

A “reliable and repeatable” system for evaluating patients with diabetes ahead of cataract surgery and caring for them afterward could reduce the likelihood of complications, according to a study published in Clinical Ophthalmology.
“Patients with [diabetes mellitus] who undergo cataract surgery can have variable outcomes due to postoperative sequelae. Of these, the most common reported in the literature include pseudophakic macula edema and diabetic macula edema,” Christolyn Raj, MBBS, MMed, MPH, FRANZCO, of the University of Melbourne in Australia, and colleagues

How to be a vaccine advocate in the era of disinformation

Recent resurgences of vaccine-preventable infections underscore the importance of combating misinformation and disinformation about vaccines.
Opposition to vaccination is not new. Vaccine hesitancy has existed since Edward Jenner developed the smallpox vaccine. However, there has been a significant increase in vaccine hesitancy and declines in vaccination rates, especially over the last decade.
In 2019, WHO recognized vaccine hesitancy as one of the top threats to global health. Vaccine hesitancy threatens to reverse progress made in tackling vaccine-preventable diseases, and it appears the

‘Forever chemicals’ linked to aggressive breast cancer subtype

Exposure to two of the most common “forever chemicals” may increase risk for an aggressive form of breast cancer, according to an NIH analysis.
Women with higher blood levels of the per- and polyfluoroalkyl substances (PFAS) appeared more likely to develop ER-negative disease, a subtype associated with higher likelihood of early recurrence and poorer survival.
The results — which showed 67% to 93% increases in relative risks among those with the greatest exposure — have considerable public health implications, according to study co-author Alexandra White, PhD, MSPH, NIH Stadtman Investigator

Earn CME, develop care strategies at IBD NOW Summit

The 10th annual IBD NOW Summit for Fellows will be held virtually on Saturday, Nov. 7, and feature interactive sessions and case presentations aimed at deepening insight into inflammatory bowel disease management.
The free CME event will run from 9 a.m. to 12 p.m. Eastern time.
“The talks range from more straightforward management to nuances of IBD care that will appeal to all years of trainees,” Corey A. Siegel, MD, MS, Constantine and Joyce Hampers Professor of Medicine at Geisel School of Medicine at Dartmouth and director of the Walter and Carole Young Center for Digestive Health, told