Pickleball players mostly wear regular eyeglasses on court

Amateur pickleball players report that their regular prescription eyeglasses are the most common eyewear they use on the court, despite safer options and a rising rate of eye injuries, according to a study published in JAMA Ophthalmology.
“Pickleball has surged in popularity in recent years and is enjoyed by players of all ages and skill levels. Accordingly, pickleball-related injuries have become more common, with a nearly sevenfold increase in injuries between 2017 and 2022,” Daniel Henick, MD, a hospital resident at Yale School of Medicine, and colleagues wrote. “While

VIDEO: Pembrolizumab regimen another option for platinum-resistant ovarian cancer

In this video, Ursula A. Matulonis, MD, shares insight on the phase 3 KEYNOTE-B96 trial of pembrolizumab combination therapy vs. placebo in patients with PD-L1-positive, platinum-resistant ovarian cancer.
In the trial, presented at the Society of Gynecologic Oncology Annual Meeting on Women’s Cancer, patients received pembrolizumab (Keytruda, Merck) plus weekly paclitaxel, with or without bevacizumab (Avastin, Genentech), or placebo.
Matulonis, chief of the division of gynecologic oncology at Dana-Farber Cancer Institute, reported improvements in PFS and OS with the pembrolizumab regimen

Recent Annals of Internal Medicine articles clinicians should be aware of

SAN FRANCISCO — A speaker at ACP’s Internal Medicine Meeting discussed several articles recently published in Annals of Internal Medicine that are of particular relevance to primary care providers.
During the presentation, Christina Wee, MD, MPH, FACP, senior deputy editor and vice president of Annals of Internal Medicine, highlighted articles that generated high views, almetric scores and attention from media, were topical to clinical practice, and are a priority area for ACP.
Among the articles was a Danish-based nationwide cohort study, where the researchers found that aluminum-adsorbed

Dispel fears of refractive therapeutic surgery in keratoconus

In this exclusive interview with Healio, Cosimo Mazzotta, MD, PhD, one of the pioneers of corneal cross-linking, reverses the conventional view of laser refractive surgery as a potentially harmful procedure in eyes with keratoconus.
This topic has divided the field between physicians who view the procedure as dangerous and those who consider it a viable option in select patients. According to Mazzotta, advanced CXL protocols combined with new ray tracing methods of ocular system analysis have made laser refractive surgery a safer, data-driven approach to corneal remodeling. In certain patients

VIDEO: Relacorilant regimen ‘definitely an option’ for platinum-resistant ovarian cancer

In this video, Ursula A. Matulonis, MD, discusses results from the phase 3 ROSELLA trial, which assessed the combination of relacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer.
The data, presented at the Society of Gynecologic Oncology Annual Meeting on Women’s Cancer, showed statistically significant improvements in PFS and OS among patients randomly assigned relacorilant (Lifyorli, Corcept Therapeutics) plus nab-paclitaxel (Abraxane, Bristol Myers Squibb) vs. nab-paclitaxel alone.
“This trial led to the full FDA approval of relacorilant and Abraxane

AI highlights link between early-onset CRC, gut microbiome

An AI-assisted analysis of the gut microbiome in colorectal cancer cases revealed substantial differences between early- and late-onset disease, including microbial diversity and associations with specific mutations.
The research, presented at American Association for Cancer Research Annual Meeting, also showed variations within early-onset colorectal cancer based on genetics and social determinants of health, including education and BMI.
“Early-onset colorectal cancer is a biologically and contextually distinct disease, and we need to approach it differently,” Enrique Velazquez-Villarreal, MD,

Implantable shock absorber may improve medial knee OA outcomes

NEW ORLEANS — An implantable shock absorber may provide sustained pain relief, high rates of survivorship and functional improvement in patients with medial knee osteoarthritis, according to results presented here.
“Anytime we are implementing novel techniques and technologies, it is important to have longer term results,” Seth L. Sherman, MD, FAAOS, associate professor of orthopedic surgery at Stanford University, told Healio about results presented at the American Academy of Orthopaedic Surgeons Annual Meeting. “This data at 5 years gives me information for my

Early maternal RSV vaccination has stronger protection for babies

MUNICH — Babies whose mothers were vaccinated against respiratory syncytial virus earlier in their third trimester had stronger protection against hospitalization during their first RSV season, according to findings presented at ESCMID Global.
The CDC and American College of Obstetricians and Gynecologists recommend pregnant women receive the RSV vaccine (Abrysvo, Pfizer) starting at 32 weeks’ gestation through 36 weeks’ gestation to protect their baby during their first RSV season. In contrast, the U.K. recommends vaccination beginning at 28 weeks’ gestation. WHO recommends vaccination during

Body image dissatisfaction common in obesity med

SAN DIEGO — Body image dissatisfaction is a critical part of obesity care, but it often goes unaddressed, according to a presentation here.
Sandy Van, MD, CCFP, DABOM, an obesity medicine physician and chief medical officer of Hims and Hers Canada, and Sandra Elia, a food addiction counselor and board chair and director of education and patient advocacy for Obesity Matters, addressed body image among patients in obesity care at the Obesity Medicine Association’s annual conference.
Healio spoke with Van and Elia to learn more about body image dissatisfaction, helping patients manage this and

New treatments for molluscum contagiosum

Molluscum contagiosum, a common and highly contagious skin infection caused by a poxvirus, affects millions of individuals each year.
Characterized by small, firm, dome-shaped bumps that may appear white, pink or skin colored, the condition is generally harmless. Lesions can develop anywhere on the body but are rarely found on the palms of the hands or soles of the feet. In some cases, the bumps may become itchy, red or swollen, which can lead to patient discomfort.
Molluscum contagiosum is most frequently seen in children aged 1 to 10 years but can occur at any age, and people can become