What Is a Research Grade Peptide and Why Does Purity Matter?

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A research grade peptide is basically a tiny chain of building blocks called amino acids. Scientists build these in a lab, in a very specific order, to study how the human body works. Now here is the thing nobody talks about enough — purity is everything. If your research grade peptide has even a small […]

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PMDD and mental health: the link goes deeper than you might think

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

Epidemiologists based out of the Karolinsa Institute, Sweden, say the relationship between premenstrual dysphoric disorder, AKA, PMDD and mental health is real and more complex than previously understood. Ever wondered whether your premenstrual hormone dips are affecting your mental health? A nationwide Swedish study finds that premenstrual disorders and psychiatric conditions are closely intertwined, and […]

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ACP issues guidance on medications for obesity, overweight

ACP has published living clinical guidance to help physicians select medications for patients with overweight or obesity.
Unhealthy weight remains a significant public health issue globally, with 68.5% of American adults and 59% of adults worldwide having overweight or obesity, according to Amir Qaseem, MD, PhD, MHA, MGIN, MRCP, FACP, ACP chief science officer and senior vice president of clinical policy at the Centers for Evidence Reviews, and colleagues.
They wrote in Annals of Internal Medicine that first-line treatments for obesity and overweight include physical activity and nutrition, but

Q&A: Ocular surface disease in children ‘actually quite common’

Ocular surface disease is more common in children than previously believed, raising the risk for underdiagnosis and presenting an “urgent” need for child-centric clinical trials.
“While adult ocular surface disease has transitioned into a well-defined subspecialty with a robust therapeutic pipeline, pediatric patients remain ‘therapeutic afterthoughts,’’” Kaleb Abbott, OD, MS, FAAO, FOWNS, and colleagues wrote in a letter to the editor in The Ocular Surface. “However, emerging data show [ocular surface disease] is common in children and outpaces

Bio-interventional scleral reinforcement shows safety

WASHINGTON — A scleral reinforcement procedure resulted in minimal endothelial cell loss, according to a study presented at the American Society of Cataract and Refractive Surgery meeting.
Arsham Sheybani, MD, ABO, presented data on the endothelial health of eyes that underwent bio-interventional scleral reinforcement of cyclodialysis cleft with CycloPen (Iantrek).
“As we all know, with the CyPass micro-stent [Alcon] that had been recalled, there were concerns with endothelial health, especially in cases where it had been left too far into the anterior chamber,” he told Healio.
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Sheybani

Expert: It’s time to vaccinate US dairy cattle against bird flu

Gregory C. Gray, MD, MPH, FIDSA, wants to get the word out: The time is now to vaccinate U.S. dairy cattle against bird flu.
“While vaccines in poultry are an active area of investment, it now seems of paramount importance to additionally employ similar strategies in U.S. dairy cattle,” Gray, a professor of infectious disease epidemiology at The University of Texas Medical Branch, and colleagues wrote in a commentary published in The Journal of Infectious Disease.
Since the beginning of the outbreak of highly pathogenic avian influenza A(H5N1) in U.S. dairy cattle in March 2024, more than 1,141

Hook of hamate fractures in twin collegiate baseball players

A 19-year-old, right-hand-dominant, male, National Collegiate Athletic Association division 1 baseball catcher presented with left volar-ulnar wrist pain and small finger numbness that started during athletic competition.
Game video footage revealed that the ulnar side of his left hand struck the opposing player’s helmet. Physical examination revealed hook of hamate tenderness with decreased small finger sensation and finger abduction weakness. Wrist radiographs (anteroposterior, lateral and carpal tunnel view) showed a suspected hook of hamate fracture (Figure 1). MRI revealed a displaced

SGLT2s linked to risk for diabetic foot complications vs. GLP-1s

CHICAGO — Major diabetic foot complications were more common in patients with type 2 diabetes treated with SGLT2 inhibitors than those treated with GLP-1 receptor agonists, researchers reported at ENDO 2026.
However, new-onset diabetic peripheral neuropathy was lower in patients taking SGLT2 inhibitors compared with those taking GLP-1s, according to the researchers.
“Diabetic foot complications, including ulcers, infections and amputations, are still a major cause of morbidity in patients with type 2 diabetes, even with newer therapies. At the same time, GLP-1 receptor agonists have been

Novel agent may be ‘launching point’ in chondrosarcoma

CHICAGO — A novel tetravalent DR5 agonist could become the first standard of care for conventional chondrosarcoma.
Updated data from the first positive randomized trial in this disease showed ozekibart (INBRX-109, Inhibrx Biosciences Inc.) doubled median PFS and improved multiple other efficacy outcomes compared with placebo.
The magnitude of benefit — though modest by typical oncology standards — exceeds what has been achieved with other agents in this setting.
“There are no FDA-approved therapies for this disease, so the unmet need is substantial,” researcher Dale Shepard, MD, PhD, codirector

‘It is on all of us’ to educate patients about congenital CMV

Congenital cytomegalovirus occurs in one out of every 200 babies and is the most common infectious cause of hearing loss and developmental disabilities.
But despite how common it is, most parents have never heard of it until their baby is diagnosed.
Megan H. Pesch, MD, MS, a developmental pediatrician at the University of Michigan, did not feel like she had enough information about CMV until her daughter was diagnosed 7 years ago.
“What we learned in residency was that babies with CMV are born looking very sick with these terrible rashes, and they have small heads and severe jaundice,” Pesch