Why Cancer Misdiagnosis Happens More Often Than You Think: Causes, Consequences, and Patient Options

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Most patients trust their cancer diagnosis. That trust is often warranted—but it probably shouldn’t be unconditional, particularly when the initial findings are subtle, ambiguous, or delivered quickly in a busy clinical setting. A 2013 study in BMJ Quality & Safety estimated that roughly 12 million American adults experience a diagnostic error in outpatient care every […]

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What to Know About Dietary Formulations and Health Benefits

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Most people grab a vitamin bottle without a second thought for the science inside. Each pill starts as a simple pile of raw powder in a lab. Experts must study how these tiny grains act when they mix together. They want to be sure your body can use what is in the dose. A bad […]

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The Medical Importance Of Emotional Support During Times Of Loss

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The mind and body are both affected by grief. It may disrupt such things as sleep patterns, energy, appetite, and overall mental health. In medicine, support for the emotions is increasingly appreciated as a necessary part of convalescing from grief. This article, it explains how emotional help works, which is to provide and maintain psychological […]

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Allograft MPFL reconstruction may do worse vs. autograft

NEW ORLEANS — Results showed patients who underwent a medial patellofemoral ligament reconstruction with either an allograft or autograft experienced similar complications, but the allograft group trended toward worse clinical outcomes.
“Ultimately, this is something that we should continue to look at, and we should follow this cohort for an additional amount of time to see if this trend continues,” Lasun O. Oladeji, MD, PhD, assistant professor of clinical orthopedics at the University of Miami, told Healio about results presented at the American Academy of Orthopaedic Surgeons Annual

Pfizer will seek approval for its Lyme disease vaccine

Pfizer said its experimental Lyme disease vaccine was more than 70% efficacious in reducing confirmed cases of the tickborne illness in a phase 3 trial, although the trial missed its primary endpoint.
The drugmaker said it will pursue regulatory approval of the vaccine, which it is developing with Valneva. Last year, Valneva said it expected Pfizer to launch the vaccine in U.S. and European markets in the second half of 2027, pending approval.
“The efficacy shown in the VALOR study of more than 70% is highly encouraging and creates confidence in the vaccine’s potential to protect against this

Obesity-linked organ hyperplasia may drive cancer risk beyond BMI

A multicomponent study has yielded new insights into how obesity increases risk for certain types of cancer.
The findings suggest hyperplasia — an increase in the number of cells within an organ — contributes to the development of at least some solid tumors.
“There are other ways in which obesity increases cancer, but this is a major mechanism,” Cristian Tomasetti, PhD, director of City of Hope’s Center for Cancer Prevention, Early Detection and Monitoring, told Healio.
Obesity increases risk for 13 malignancies, including breast, colorectal, pancreatic, liver and kidney cancers, according to

Laser eye surgeons should be vigilant for P. lilacinum infection

Three patients contracted fungal keratitis after undergoing laser eye surgery at a New York City clinic in December 2024, according to a report in Morbidity and Mortality Weekly Report.
When the patients reported eye pain and vision loss after surgery, the clinic sent corneal specimens to a clinical laboratory that returned findings of fungal elements on microscopy. Cultures later revealed Purpureocillium lilacinum in two of the patient specimens. The laboratory then notified the New York City Health Department, according to the report.
Michelle E. Chang, MD, and colleagues wrote that the first

Concussions predict depression, anxiety in athletes

Risks for anxiety and depression increased among former college athletes with three or more lifetime concussions, according to findings published in Neurology.
Steven Broglio, PhD, ATC, director of the University of Michigan Concussion Center, and colleagues aimed to assess associations between sports-related head injuries and physical, mental, cognitive and behavioral health measures.
“Concussions are prevalent among young athletes participating in contact and collision sports,” Broglio said in a press release.
“While many studies have examined the effects of concussion

ACP updates outpatient COVID-19 treatment guidance

Updated guidance from ACP revealed the best practices for treating confirmed cases of COVID-19 in an outpatient setting, including the use of medications.
Amir Qaseem, MD, PhD, MHA, MGIN, MRCP, FACP, ACP’s chief science officer and senior vice president of clinical policy at the Centers for Evidence Reviews, and colleagues published the recommendations in Annals of Internal Medicine. The Population Health and Medical Science Committee has decided to retire the subject from its living status, according to the guideline.
Healio spoke with Qaseem to learn more about the ACP’s recommendations, what

Interrupting or stopping GLP-1s may reverse cardiovascular benefits

Stopping or interrupting GLP-1 receptor agonists “erode and could ultimately reverse” their cardiovascular benefits, increasing the risk for major adverse cardiovascular events, researchers wrote in BMJ Medicine.
“There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop,” Ziyad Al-Aly, MD, a clinical epidemiologist at Washington University School of Medicine in Saint Louis, said in a press release. “Many quit after a few months because of cost, side effects or shortages. When they stop, it’s not just weight that comes back; they