WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2026, John P. Berdahl, MD, of Vance Thompson Vision, discusses how to improve nocturnal IOP.
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Berdahl said there is evidence that elevated IOP at night can lead to glaucoma progression. One possible solution is for patients to wear ocular pressure adjusting pump goggles (Fsyx, Balance Ophthalmics) at night to lower eye pressure.
“The first thing that we need to do is understand glaucoma better, recognize that nighttime is vulnerable,” he said. “Current therapies don’t work very well at night outside of

WAIKOLOA, Hawaii — In a panel discussion at Orthopedics Today Hawaii, Clifford B. Jones, MD, FAAOS, FAOA, FACS, delivered his pearls on ankle syndesmosis reduction.
“Open reductions do the best,” Jones said in his presentation. “Avoid clamps and use your thumb; stable fixation with either endobuttons or screws; and then what assists your syndesmotic fixation is going to be reducing the fibula and then the anterior posterior collicular components.”
According to Jones, professor and chair at Creighton Medical School — Phoenix, chief of orthopedic surgery at Dignity Health — Arizona, and clinical

Patients with infantile nystagmus had significant gains in near and distance visual acuity as well as stereopsis following regular sessions of vision training with RevitalVision software, according to a study.
“Visual perceptual learning is a process whereby visual interpretation and comprehension are enhanced through practice,” Idan Hecht, MD, of the department of ophthalmology at Shamir Medical Center in Israel, and colleagues wrote in British Journal of Ophthalmology. “This phenomenon, rooted in the brain’s plasticity, has the potential to improve visual detection

The FDA granted orphan drug designation to OpCT-001 for the treatment of retinitis pigmentosa, according to a press release from BlueRock Therapeutics.
The investigational induced pluripotent stem cell-derived cell therapy is currently being evaluated in the phase 1/2a CLARICO study.
OpCT-001 is designed to replace lost retina cells with new functional cells, which may restore vision, according to the release.
“Receiving orphan drug designation for retinitis pigmentosa is an important milestone for the OpCT-001 program,” Amit Rakhit, MD, MBA, chief medical officer of BlueRock, said in the

Exposure to wildfire smoke during the final months of pregnancy may raise the risk for autism in infants by up to 23%, a study published in Environmental Science & Technology indicated.
The data do not conclusively tie the disorder to wildfire exposure or “answer any direct questions about the mechanisms, but it can help us pinpoint discrete developmental events or stages which may be important for autism development,” David Luglio, PhD, a post-doctoral fellow at Tulane University, told Healio.
“Protection of pregnant women from wildfire smoke exposure, especially in the third trimester,

The FDA’s Center for Devices and Radiological Health issued an early alert warning of packaging failures that could lead to a breach in the sterile barrier for MediHoney Wound and Burn products and certain lots of CVS Wound Gel.
As of Dec. 19, 2025, 11 serious injuries related to MediHoney Wound and Burn products and three serious injuries related to CVS Wound Gel products have been reported by Integra LifeScience, according to the alert. There are no deaths linked to this issue, the FDA said.
According to the alert, the manufacturer, Integra LifeSciences, has notified affected customers and

Researchers at the NIH and Emory School of Medicine have completed the first minimally invasive coronary artery bypass of the left main stem before transcatheter aortic valve replacement.
Ventriculo-coronary transcatheter outward navigation and reentry (VECTOR), a closed-chest, transcatheter, coronary ostial bypass procedure, was performed for the first time in a human, a 67-year-old man with aortic and mitral valve replacements and decompensated heart failure from severe stenotic degeneration of a previous aortic bioprosthesis.
Redo TAVR was not feasible due to the replacement’s

A once-weekly injectable glucose-dependent insulinotropic polypeptide/GLP-1 dual agonist conferred up to 14.7% weight loss at 13 weeks for adults with overweight or obesity, according to findings from the VENTURE trial published in Obesity.
As Healio previously reported, VK2735 (Viking Therapeutics) was associated with weight loss of up to 7.8% at 28 days in a phase 1 study. In new data from a phase 2 dose-ranging trial, researchers found weight loss continued to increase up to 13 weeks for adults with overweight or obesity.
“The efficacy of VK2735 was robust with no indication of a plateau at

The FDA has approved the first prescription, at-home neuromodulation therapy for individuals with major depressive disorder who have failed at least one prior antidepressant, according to the manufacturer.
In a press release, Neurolief Inc. said it developed ProLivRx to deliver focal, multichannel, external non-invasive Combined Occipital and Trigeminal Afferent Stimulation (eCOT-AS) via gentle electrical pulses aimed at mood-influencing neural networks.
“ProLivRx offers new hope,” Owen S. Muir, MD, DFAACAP, chief medical officer at Neurolief, told Healio. “Not only did ProLivRx lead to relief

An analysis of more than 88,000 U.S. adults provides new insights into how duration and extent of alcohol consumption may affect colorectal cancer risk.
Current and consistent heavy alcohol intake throughout adulthood appeared associated with a near-doubling of risk compared with current, consistent light drinking, data from a population-based randomized screening trial showed.
Higher lifetime alcohol consumption also appeared associated with significantly higher risk, particularly for rectal tumors.
In addition, the findings suggested benefits of alcohol cessation, including lower odds for