Navigating Nutraceuticals: Urolithins

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Learn what urolithins are, what they do and where you get them with MNB’s quick guide to nutraceuticals. What are urolithins? Urolithins are a type of antioxidant that can prevent damage to the proteins in our cells, protect our DNA and interact with a variety of cellular processes. They are made from tannins, a type […]

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ACOG updates cervical cancer screening guidance to include self-collection option

ACOG issued updated guidelines on screening for cervical cancer that align with recent recommendations from the Health Resources and Services Administration’s Women’s Preventive Services Initiative.
The guidance for the first time includes the option for patients aged 30 to 65 years at average risk for cervical cancer to collect their own samples with FDA-approved testing kits for primary high-risk HPV (hrHPV) screening every 3 years, according to an ACOG press release.
The organization advised that clinicians should only offer the option of self-collection “if patients prefer this method and

Semaglutide NAION risk higher than risk with SGLT2 inhibitors

Semaglutide was associated with more than twice the risk for nonarteritic anterior ischemic optic neuropathy compared with SGLT2 inhibitors, although the absolute risk “remained low,” according to a study published in JAMA Ophthalmology.
“Although [semaglutide is] effective for glycemic control, weight loss and cardiovascular risk reduction, nonarteritic anterior ischemic optic neuropathy (NAION) has emerged as a serious rare adverse event,” Kent Heberer, PhD, data scientist at the U.S. Department of Veterans Affairs, and colleagues wrote. “Studies show

HHS ramps up psychedelic development for mental health

Since President Donald J. Trump’s executive order to increase access to psychedelics and other alternative therapies for mental health, HHS has announced new regulatory actions and funding to support the development of these drugs.
“While there are a number of available therapies for various illnesses such as depression, substance use disorder and PTSD, many people do not respond well to these therapies,” Frederick S. Barrett, PhD, director of the Center for Psychedelic and Consciousness Research at Johns Hopkins Medicine, told Healio.
“The promise of psychedelic

Team approach needed for glaucoma surgery in pregnant patients

When considering performing glaucoma surgery in patients who are pregnant, ophthalmologists should weigh factors such as timing of surgery and type of anesthesia while prioritizing a team approach.
While data covering the impact of glaucoma surgery on pregnancy are limited, Sunita Radhakrishnan, MD, said that the risk profile is different compared with common non-obstetric surgeries.
“Eye surgery has a relatively short duration,” she said in a presentation at the American Glaucoma Society meeting. “It can be performed under local anesthesia, and there is very minimal postoperative pain, which

Hair loss in women ‘increasingly mentioned’

SAN FRANCISCO — Primary care providers can help diagnose and treat hair loss in women, according to a speaker here.
“In my practice, hair loss is an increasingly mentioned patient concern, and I believe that is probably also reflected in the patients that you see as well,” Ashley B. Wentworth, MD, a dermatologist affiliated with Mayo Clinic practicing in Jacksonville, Florida, said in her presentation.
According to the Cleveland Clinic, female-pattern hair loss impacts 30 million people in the U.S., and more than 50% will “experience noticeable hair loss.” So, Wentworth offered a case-based

FDA issues complete response letter for trenibotulinumtoxinE

The FDA issued a complete response letter regarding AbbVie’s biologics license application for trenibotulinumtoxinE, a fast-acting botulinum toxin, requesting more information about its manufacturing processes, according to a press release.
The complete response letter did not cite any safety or efficacy concerns for trenibotulinumtoxin E, also known as TrenibotE, and did not request additional clinical studies, according to the AbbVie release.
“We strongly believe trenibotulinumtoxinE is an important innovation in botulinum toxin science, with the potential to expand options for patients

VIDEO: Early treatment with pegcetacoplan saves years of GA progression

In this video from the Macula Society meeting, Dilsher S. Dhoot, MD, FASRS, of California Retina Consultants, discusses 5-year data on pegcetacoplan for geographic atrophy secondary to age-related macular degeneration.
The results showed the long-term efficacy of continuous Syfovre (pegcetacoplan injection, Apellis) treatment in patients with GA and the benefits of earlier treatment vs. delayed treatment, according to a study abstract.
“We see [that] earlier treatment initiation preserved two times [the amount] of retinal tissue vs. delayed treatment,” Dhoot told Healio. “We

Wildfire smoke may raise risk for several cancers

Exposure to wildfire smoke may raise risk for several types of cancer, according to an analysis of data from a large trial.
The elevated risk — observed for five cancer types — may occur after only relatively low levels of exposure experienced by large segments of the general population, findings presented at American Association for Cancer Research Annual Meeting showed.
“Wildfires are becoming more common and more intense,” Shuguang Leng, MBBS, PhD, associate professor at The University of New Mexico Comprehensive Cancer Center, told Healio. “It is important to increase public awareness that

Q&A: The role of robotics in the future of orthopedics

With the recent growth in utilization of robotic tools and AI learning modules in orthopedic practices around the country, surgeons must now adapt to a new status quo in the OR.
According to Joseph P. Iannotti, MD, PhD, professor of orthopedic surgery at Cleveland Clinic Lerner College of Medicine, utilization of these technologies will only increase in the future, with more emphasis on computer vision and shared decision-making.
“At some point, an AI module will say, ‘I have analyzed 10,000 of these procedures already. I suggest that this is the right next step for this patient,’”