FDA widens Ryaltris approval, now for patients 6 years and older

The FDA approved Ryaltris nasal spray for treating seasonal allergic rhinitis symptoms in children aged 6 years to less than 12 years, meaning it is now approved for patients aged 6 years and older, according to a press release.
The fixed-dose combination Ryaltris (Glenmark Pharmaceuticals) nasal spray was approved for adults and children aged 12 years and older in 2022. It is made up of the antihistamine olopatadine hydrochloride (665 µg) and the corticosteroid mometasone furoate (25 µg).
According to the release, data from a randomized, double-blind, placebo-controlled phase 3 study published

Tobramycin plus vancomycin may not reduce infection rate

Intrawound tobramycin powder plus vancomycin powder did not reduce deep surgical site infections in patients with periarticular tibial fractures at high risk for infection compared with vancomycin powder alone, according to results.
“Biology is complicated. The logic of this trial and the reason so many clinicians are using tobramycin seems sound, but in practicality it did not work. In fact, for the subgroup of open fractures, the addition of tobramycin may make it worse,” Robert V. O’Toole, MD, Hansjrg Wyss Medical Foundation endowed professor in orthopedic trauma in the

Cures Act complicates dissemination of cancer test results

What if you found out you had cancer while attending a wedding? Or before a job interview? Or while reading a bedtime story to your child?
How about when you are home and alone with no semblance of what the test results mean?
David E. Gerber, MD, medical oncologist and professor at Simmons Comprehensive Cancer Center at UT Southwestern Medical Center, has heard all these stories.
In 2021, the information-blocking provision of the 21st Century Cures Act went into effect, requiring hospitals and medical institutions to immediately release nearly all patient test results.
“The Cures Act’s

Deadly NYC Legionnaires’ disease outbreak has a familiar source

A fourth person has died in the Legionnaires’ disease outbreak that has hospitalized dozens of people in Manhattan’s Upper East Side, health officials announced Monday.
The announcement came a few hours after New York City Health Commissioner Alister F. Martin, MD, posted on social media that the outbreak’s source has “likely been eliminated” and “we have not seen anyone with new symptoms in over a week.”
As of late Monday, the New York City Department of Health and Mental Hygiene has reported at least 76 cases in the outbreak, including 60 hospitalizations.
An investigation has linked the

Microperimetry helps track structure, function in GA

LAS VEGAS — Customized microperimetry helped researchers track geographic atrophy in patients undergoing CTx001 gene therapy, according to a presentation at Clinical Trials at the Summit.
Arshad Khanani, MD, MA, FASRS, of Sierra Eye Associates in Reno, Nevada, presented initial findings from the first cohort of patients enrolled in the phase 1/2 Opti-GAIN study. The primary endpoints are safety and tolerability of CTx001 (Complement Therapeutics) as well as change in ellipsoid zone attenuation at 52 weeks vs. baseline, according to the presentation.
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Khanani said the study implemented

Mobile skin clinic expands dermatologic care to underserved communities of Minnesota

A mobile skin clinic in Minnesota is bringing free dermatologic care to underserved communities with the goal of enhancing longitudinal care with increased access to skin cancer screenings, dermatologic evaluations and treatment.
Fourth-year medical students Divya Alley and Kenny Ta founded the clinic with a team of colleagues from University of Minnesota through the Mobile Health Initiative, launched by the university’s Office of Academic Clinical Affairs in 2020 to help deliver mobile health care around the state in partnership with local community organizations. With the support of the

Epioxa provides patient comfort, quicker recovery time

KIAWAH ISLAND, S.C. — In this video from Kiawah Eye & Retina, Beeran B. Meghpara, MD, highlights the benefits of Epioxa from Glaukos in the treatment of keratoconus.
“I think 2026 is going to be a great year for cornea specialists, especially those that are interested in keratoconus,” Meghpara, of Wills Eye Hospital, said. “This year, we finally have access to an FDA-approved epithelium-on cross-linking procedure, so Epioxa is something we’re all really excited about. … Patients are more comfortable, the recovery time is quicker, and the infection rate is lower.”

Center-level decisions impact heart transplant disparities

Khadijah Breathett, MD, MS, FACC, FAHA, FHFSA, and colleagues have been at the forefront of research on disparities in heart transplantation.
The group’s most recent paper indicates that racial disparities in acceptance of a first offer of a donor heart may be tied to the decision-making process at the individual center level.
Centers with a higher proportion of Black patients and a lower proportion of white patients had lower acceptance rates of a first offer of a donor heart compared with centers with a lower proportion of Black patients and a higher proportion of white patients, and

Physical activity rates up in short daily home dialysis vs. ICHD

Patients receiving short daily home dialysis reported better habitual physical activity rates and other quality of life improvements vs. patients receiving in-center hemodialysis, according to study data published in Kidney360.
Understanding both clinical and patient-centered outcomes across different dialysis modalities could help support patient-centered approaches to care, according to Bernard Canaud, MD, PhD, emeritus professor of nephrology at Montpellier University School of Medicine, France, and colleagues.
“Physical activity is increasingly recognized as a meaningful indicator of