Fracture-specific infection criteria more accurate than CDC

NASHVILLE — A classification system specific to fracture-related infections captured more cases of infection than the CDC surgical site infection definitions outside a 90-day window, according to results presented here.
“The CDC criteria are widely adopted for public health reporting and hospital quality metrics, but they were developed for general surgical procedures and specifically account for the biologic and mechanical complexities of fracture fixation and the potential for latent implant-related infection,” Abhishek Ganta, MD, an orthopedic trauma surgeon at New York University Langone

FDA approves Ryzumvi eye drop for presbyopia

The FDA approved a supplemental new drug application for Ryzumvi, a preservative-free eye drop, for the treatment of presbyopia.
“Presbyopia affects approximately 90% of Americans over age 45, making everyday activities like reading, using smartphones and working on computers increasingly difficult. Many patients rely on reading glasses or other corrective lenses, creating a significant need for convenient, noninvasive treatment options,” George Magrath, MD, MBA, MS, CEO of Opus Genetics, told Healio. “Phentolamine ophthalmic solution 0.75% offers a pharmacological alternative designed to

Study: Many healthcare workers have lingering long COVID symptoms

A multicenter cohort analysis revealed that more than 1 in 10 healthcare workers in the United States endure moderate-to-severe long COVID symptoms that can linger for months.
The findings “highlight the personal toll” COVID-19 has placed on healthcare workers (HCWs), study author Eric Kontowicz, PhD, MPH, told Healio.
“Many continued caring for patients through repeated exposures, and for some, that cost has lasted well beyond their initial infection,” said Kontowicz, an associate research scientist at the University of Iowa.
The study included 1,742 participants who tested positive for

FDA approves Brytly redness-relieving drop

Editor’s note: This is a developing news story. Please check back soon for updates.
The FDA approved Brytly, a nonprescription eye drop for the relief of eye redness from minor irritations, according to a press release.
Brytly (apraclonidine ophthalmic solution, 0.125%, Alcon) is approved for people aged 12 and older and is meant to be used no more than two times per day. Contact lenses should be removed prior to use, and users should wait at least 10 minutes after applying the drops before reinserting their contacts. Users should also wait 5 minutes before applying other eye drops.
The

Sex-specific FIT thresholds could equalize CRC detection

NASHVILLE, Tenn — Fecal immunochemical tests appear more sensitive to colorectal cancer and advanced precancerous lesions in men than women, according to a retrospective study presented at ACG Annual Scientific Meeting.
“FIT is the most commonly used colorectal cancer screening test in the world, with an average sensitivity of 79% and specificity of 94%,” Thomas F. Imperiale, MD, Lawrence Lumeng Professor of Gastroenterology and Hepatology at Indiana University School of Medicine, told attendees. “Its test characteristics vary based on threshold and the brand, but whether performance varies by

Anti-VEGF may lower surgery risk with retinal vein occlusion

Anti-VEGF injections before cataract surgery may protect eyes with retinal vein occlusion from developing postoperative macular edema, according to data published in BMC Ophthalmology.
“Patients with [retinal vein occlusion] and concurrent cataract have been shown to benefit from cataract extraction to significantly improve visual outcomes,” Kevin Dahlan, MD, of the department of ophthalmology at Stony Brook University Hospital, and colleagues wrote. “However, [cataract extraction] poses challenges, as it significantly increases the risk of postoperative macular edema in

Screening identifies syphilis cases in correctional facilities

Amid a surge in syphilis cases in Alaska, an opt-out screening program implemented in Alaskan correctional facilities helped to identify new cases that would have likely been missed, according to a recent MMWR report.
“Syphilis incidence has been rapidly increasing in Alaska since 2017,” Joe McLaughlin, MD, MP, state epidemiologist and chief of the section of epidemiology at the Alaska Department of Health and Social Services, told Healio.
CDC data show a nearly 2,220% increase in reported syphilis cases in Alaska between 2016 and 2024, from 20 to 452. McLaughlin added that cases of

FDA approves Enspryng for thyroid eye disease

Editor’s note: This is a developing story. Please check back soon for comments.
The FDA approved Enspryng, an interleukin-6 inhibitor, for at-home subcutaneous treatment of thyroid eye disease, according to a press release from Genentech.
The approval was supported by findings from the phase 3 SatraGO program in thyroid eye disease (TED). In patients with active and chronic moderate to severe TED, the SatraGO-2 trial demonstrated a “significant and clinically meaningful difference” of 52.9% in proptosis response and 60.7% in diplopia reduction with Enspryng vs. 23.4% and 25.8%, respectively, in

How can pediatricians address bullying?

SAN DIEGO — Because bullying can have a profound impact on a child’s health, pediatricians play an important role in preventing and addressing it in clinical practice, according to a presentation at the AAP National Conference & Exhibition.
“Bullying is common, but that doesn’t mean we should be ignoring it and allowing it to happen or think about it as a rite of passage,” Seth J. Scholer, MD, MPH, FAAP, professor of pediatrics at Vanderbilt University Medical Center, told Healio in an interview. “It needs to be addressed.”
Bullying is associated with adverse outcomes for victims and