A Simple Guide to Preceptorships, for Students Who Don’t Know What to Expect

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A clinical preceptorship is a structured period in the early career of a healthcare professional, where they are paired with an experienced clinician – called a preceptor – for a period of on-the-job training and coaching in a real world environment. Whilst preceptorships are not always required, many roles do ask for one from newly-qualified […]

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VIDEO: Fixed-duration therapy overcomes long-term side effects, financial toxicity in CLL

ORLANDO — In this video, Shazia K. Nakhoda, MD, discusses “exciting” data from the CLL-17 trial that showed fixed-duration therapy produces similar results inpreviously untreated chronic lymphocytic leukemia.
Results presented at ASH Annual Meeting and Exposition showed similar 3-year progression-free survival rates between continuous Bruton tyrosine kinase (BTK) inhibitor monotherapy with ibrutinib (Imbruvica; Johnson & Johnson, Pharmacyclics) and fixed-duration therapy with venetoclax (Venclexta; AbbVie, Genentech) plus obinutuzumab (Gazyva, Genentech) and venetoclax

No benefit of preoperative MRI in early HR-negative breast cancer

SAN ANTONIO — Patients with stage I or II hormone receptor-negative breast cancer do not benefit from preoperative breast MRI, according to data from San Antonio Breast Cancer Symposium.
Given the comparable 5-year locoregional recurrence rates between those who underwent breast MRI in addition to diagnostic mammography and those who did not, researchers noted that “clinical benefit of MRI is lacking” and routine use is not justified for surgical planning.
“Use of breast MRI has become widespread in the care of breast cancer patients, driven by consensus within the field that MRI was more

Senate rejects legislation to extend ACA subsidies

Enhanced premium tax credits, which have made Affordable Care Act coverage more accessible, will likely expire at the end of this year, which could lead to skyrocketing health care costs for many Americans.
Dueling health care bills failed in the Senate today.
Senators rejected both a bill to extend the tax credits for 3 years and an alternate plan that would have created new health savings accounts for consumers to put toward out-of-pocket costs, according to the Associated Press.
The AP noted the arguments against each: some said the Democrat-backed extension legislation is too expensive and

Vertebral body tethering for adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis is the most prevalent spinal deformity in children, with an incidence reported between 0.47% and 5.2% worldwide.
Posterior spinal fusion is the traditional treatment option for severe, progressive adolescent idiopathic scoliosis. However, vertebral body tethering (VBT) is safe. It has become increasingly popular among patients and parents to correct adolescent idiopathic scoliosis deformity in skeletally immature patients to preserve motion over the instrumented vertebrae (Figure 1). Compared with patients treated with posterior spinal fusion, patients treated

Global ophthalmology: Learning through teaching

Even before she became a physician, Cathleen M. McCabe, MD, knew she wanted to help people across the world.
Growing up in New Hampshire, McCabe did not travel much, but her parents hosted people from more than 40 countries through a local program, including students who would live with them for a year.
“I had this idea, even as a kid, that I wanted to be able to do something impactful and make a difference,” she said. “I wanted to do that all over the world in places that didn’t have access to the kinds of things we had in the U.S.”
Before medical school, McCabe started going on trips abroad to

GLP-1s may reduce risk for cataracts, dry AMD

GLP-1 receptor agonists are not associated with increased risks for dry age-related macular degeneration or cataract development, according to two recently published studies.
The data instead showed significantly reduced risk for cataracts, as well as lower risk for dry AMD, linked with the use of GLP-1s, according to Abhimanyu Ahuja, MD, an ophthalmology resident at the Oregon Health & Science University Casey Eye Institute, and colleagues.
“Other studies have demonstrated that these medications have anti-inflammatory and neuroprotective properties,” Ahuja told Healio. “We

Infant botulism outbreak linked to formula surpasses 50 cases

A botulism outbreak linked to ByHeart infant formula has expanded to include 51 cases in 19 states as of Dec. 10, according to the CDC, which warned against using any ByHeart Whole Nutrition formula.
The CDC and FDA are investigating the outbreak, which includes 10 cases that occurred from December 2023 through July 2025. All 51 infants in the outbreak have been hospitalized.
Last month, ByHeart voluntarily recalled all of its infant formula products, including cans and single-serve packets. According to an update on the company’s website, it tested 36 samples from three lots of formula, and

AMA policy combats ‘deepfake doctors’

“Deepfake doctors” present a threat to patient trust, medicine’s most valuable currency, and regulations must be implemented to protect public health, according to an expert.
At its Interim Meeting of the House of Delegates in November, the AMA adopted a policy to expand AI training across the medical education continuum and approved a resolution to create safeguards to protect both physicians and patients from deepfake technology “in the face of what supporters say is a ‘regulatory void,’” according to an AMA press release.
Deepfake impersonators of physicians boast millions of views on social

Preoperative radiation improves immune response in breast cancer

SAN ANTONIO — Preoperative radiation improved T-cell infiltration among patients with hormone receptor-positive, HER2-negative breast cancer when administered in combination with pembrolizumab and chemotherapy, according to study results.
Findings from the randomized, phase 2 P-RAD clinical trial, presented at San Antonio Breast Cancer Symposium, also showed preoperative radiation improved treatment responses before surgery.
“Immune checkpoint inhibitors in patients with HR-positive, HER2-negative breast cancer have shown promise but are not yet FDA-approved,” Gaorav Gupta, MD, PhD, associate