How Early-Life Stress Can Shape Mental Health Decades Later

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Why Early-Life Stress Matters The effects of childhood can long outlive the childhood. Scholars have been conducting studies on how childhood stress affects emotional growth, cognitive abilities, and psychological health over a long period. The stress in early life may involve continuous fearfulness, instability, or neglect, family struggle, or any other hardship in the critical […]

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How to Choose the Right Tooth Replacement Option

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

A missing tooth changes the physical structure of the mouth and the jawbone almost immediately. Patients often notice a shift in how they chew or speak right away. Bone loss starts slowly but stays constant without a tooth root in place. Choosing a replacement requires balancing looks with long term oral health goals. The decision […]

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Judge temporarily blocks changes to US vaccine schedule

A federal judge on Monday temporarily blocked the Trump administration’s recent overhaul of the CDC’s childhood immunization schedule.
U.S. District Judge Brian E. Murphy also temporarily blocked 13 appointments to the CDC’s Advisory Committee on Immunization Practices (ACIP) made by HHS Secretary Robert F. Kennedy Jr. between June 11, 2025, and Jan. 13, 2026, and all votes taken by those members during that time.
“The appointment process, in general, and thus the full committee was tainted,” Murphy, who was appointed by President Joe Biden, wrote in his ruling.
The ruling was in response to a

Advanced imaging may aid treatment for recurrent prostate cancer

Prostate-specific membrane androgen PET/CT can help clinicians intensify or de-escalate care for men with prostate cancer who have biochemical recurrence following radical prostatectomy.
A retrospective evaluation of patients treated at UCLA showed staging from prostate-specific membrane androgen (PSMA) PET/CT before salvage radiotherapy had a significant association with PFS, and certain therapies benefited patients with specific staging more than others.
“It is helping precision medicine,” Jeremie Calais, MD, PhD, director of clinical research in the Ahmanson Translational Theranostics

Could AI improve available treatments for geographic atrophy?

Click here to read the Cover Story, “Specialists navigate changing, challenging landscape of geographic atrophy management.”
Geographic atrophy management could benefit greatly from the combination of novel therapies and AI-driven imaging technology.
However, while our U.S. colleagues have FDA-approved complement inhibitors available but no tools, in Europe, we have approved tools, namely the RetInSight/Topcon GA Monitor, but not the treatments. While we wait to hopefully have access to both in Europe and the U.S., how can we take best advantage of this situation?
Obviously, we can provide

FDA approves third RSV vaccine for high-risk younger adults

The FDA has approved a third respiratory syncytial virus vaccine for high-risk adults aged younger than 50 years — a population the CDC has not yet recommended be vaccinated.
GSK announced that the FDA expanded the approval of the vaccine, Arexvy, to include adults aged 18 to 49 years who are at an increased risk for lower respiratory tract disease from RSV.
The CDC currently recommends RSV vaccination for all adults aged 75 years or older and for adults aged 50 to 74 years who are at high risk for severe RSV disease.
Arexvy and two other FDA-approved RSV vaccines — Abrysvo (Pfizer)

Patients undergoing RSA struggle with activities of daily living

NEW ORLEANS — Patients who underwent primary reverse shoulder arthroplasty had more difficulty with certain activities of daily living vs. those who underwent primary anatomic total shoulder arthroplasty, according to results.
“Patients want to know the best-case scenario and the worst-case scenario,” Jie J. Yao, MD, of NYU Langone Health, told Healio about results presented at the American Academy of Orthopaedic Surgeons Annual Meeting. “Understanding the types of things they may or may not be able to do is important. Both reverse shoulder arthroplasty and anatomic

VIS-101 shows safety, rapid efficacy in wet AMD

Editor’s note: This is a developing news story. Please check back soon for updates.
A dual VEGF-A and angiopoietin-2 inhibitor provided fast, durable treatment for wet age-related macular degeneration in a phase 2a study, according to a press release from NovaBridge.
NovaBridge and subsidiary Visara announced topline results from the phase 2a study of VIS-101 for the treatment of wet AMD. VIS-101 is a dual VEGF-A and ANG-2 inhibitor designed to provide more binding sites and increase VEGF-A and ANG-2 affinity, according to the release.
In the study, 38 patients in China with wet AMD were

Qlaris Bio appoints new CEO Fred Guerard

Qlaris Bio appointed Fred Guerard, PharmD, as its president and CEO, according to a press release.
The company is entering phase 3 development of QLS-111, a novel eye drop for lowering IOP in patients with open-angle glaucoma and ocular hypertension (OHT). In a statement to Healio, Guerard said he is coming to the company at an important time, with “promising results” coming out of the phase 2 Osprey and Apteryx clinical trials.
“As QLS-111 advances into phase 3 clinical development, Qlaris Bio is at a pivotal moment — building on encouraging clinical data and a

Bimekizumab does not increase depression, suicide risk vs. other psoriasis biologics

People with psoriasis prescribed bimekizumab have no greater risk for major depressive disorder or suicidal ideation than those prescribed IL-23 inhibitors, according to an analysis of TriNetX data published in JAAD International.
Data show psoriasis is associated with psychological burden and risk for major depressive disorder, and bimekizumab (Bimzelx, UCB) includes a label warning that the drug may increase risk for suicidal ideation and behaviors.
“The [drug] label says that this IL-17 inhibitor can potentially increase your risk for depression and suicidal ideation, so a lot of clinicians