Metabolic weakness uncovered in relapsed lung tumours 

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Scientists have discovered a metabolic “Achilles heel” in relapsed lung tumours - a dependence on ketones for energy. These tumours, which have survived cancer therapy, become reliant on ketones for survival.

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Questions to Ask Before Using Alertness Medicines

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You feel it at 2:30 pm, when your eyelids fight and your notes stop making sense. The coffee that helped at 10 now tastes bitter and does nothing much at all. That slump can feel risky when driving, caring for kids, or operating equipment during shifts. Before you weigh medicines, start with grounded questions about […]

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Creating Resilience with Supportive Employment in Brisbane

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In modern Australia, resilience has come to the fore as one of the major determinants of individual health and organisational performance. From a clinical and organisational health perspective, resilience is more than a psychological characteristic; it is a multidimensional concept created by biological, psychological, and social elements. Health professionals increasingly acknowledge that work environments can […]

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Review: Leafy green vegetables may lower glaucoma risk

Eating leafy green vegetables is “consistently associated with” a lower risk for developing primary open-angle glaucoma, according to data published in Nutrients.
“Growing evidence suggests that lifestyle factors — particularly dietary patterns and specific nutrients, as well as exercise, smoking, sleep, alcohol and caffeine — may modulate underlying pathophysiological mechanisms of glaucoma,” Akiko Hanyuda, of the Keio University School of Medicine, in Japan, and colleagues wrote. “If these exposures can be harnessed to favorably shift [mechanisms of

Gut microbiome has multifaceted role in ocular health and disease

In recent decades, the microbiome has emerged as a dynamic ecosystem, an “invisible organ” that plays a crucial role in systemic health and, more recently, in ophthalmology.
When naturally balanced, this complex community of microorganisms and genetic material can fulfill multiple functions that are essential to a person’s well-being. Recent research has shown that when this balance is disrupted, a complex cascade of inflammatory and immune responses could potentially pave the way to the onset of numerous conditions, including eye diseases.
“There is emerging evidence from animal models, also

Q&A: Self-hypnosis effectively reduces hot flashes

Self-hypnosis is an accessible, effective treatment for hot flashes, according to an expert.
Gary Elkins, PhD, professor of psychology and neuroscience at Baylor University, and colleagues conducted a single-blind, randomized clinical trial with 250 postmenopausal women to evaluate how effective self-administered hypnosis might be for the treatment of hot flashes.
The researchers found that the clinical hypnosis group reported a much greater reduction in hot flash scores and less daily interference compared with the control group, indicating self-administered hypnosis could be a clinically

Newborn with desquamation, enlarged spleen, liver

A vigorous, healthy-appearing newborn boy is brought to the local emergency room for evaluation after a spontaneous home delivery. His vital signs are normal, and he is feeding well.
However, his examination revealed significant widespread desquamation (all figures) with several generally distributed rust- or copper-colored spots (Figures 1, 2 and 3), with a few plaques (Figure 4, a plaque faintly seen at the tip of the examiner’s third finger) and some blisters of irregular size and shape on both hands and left foot (Figures 5, 6 and 7).
 
His abdominal exam revealed a full abdomen with

Transseptal mitral valve replacement system approved

Edwards Lifesciences announced its transseptal mitral valve replacement system received FDA approval for the treatment of symptomatic moderate-to-severe or severe mitral regurgitation.
The femoral-delivered mitral valve replacement system (Sapien M3) is indicated for patients unsuitable for surgery or transcatheter edge-to-edge repair therapy, according to a company press release.
The system is also indicated for patients with symptomatic mitral valve dysfunction associated with mitral annular calcification who are unsuitable for surgery or transcatheter edge-to-edge repair therapy, according

Andexanet alfa pulled from U.S. market due to thromboembolic risk

AstraZeneca withdrew andexanet alfa, an antidote to several direct oral anticoagulants, from the U.S. market, ending U.S. commercial sales and manufacturing of the recombinant modified human factor Xa protein, the FDA announced.
The FDA determined risks of the product (Andexxa), including serious and fatal thromboembolic events, outweigh its benefits, and communicated its position to the manufacturer following a meeting of the Cellular, Tissue and Gene Therapies Advisory Committee in 2024, according to an agency safety communication.
As Healio previously reported, the FDA approved andexanet

Pregnancy-related cardiovascular complications rising

The burden of maternal cardiometabolic comorbidities and incident pregnancy-related CV complications has increased substantially over the past 20 years in the United States, according to recent research.
“We have seen a steady, decades-long rise in both baseline cardiovascular risk at conception and the downstream complication rates in a relatively young population. Women are entering pregnancy less healthy and, as a result, experiencing more cardiovascular complications,” Emily S. Lau, MD, MPH, co-director of the Mass General Brigham Women’s Heart Health Program and assistant professor at