Phase 3 SEQUOIA Trial Reports Long-Term PFS with Zanubrutinib in Treatment-Naïve CLL/SLL

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The Phase 3 SEQUOIA trial offered long-term outcomes in the American Society of Hematology Congress. The chronic lymphocytic leukemia or small lymphocytic lymphoma patients who had not obtained a remedy had been observed by the researchers for almost six years. The sufferers who took the BTK inhibitor Zanubrutinib had a longer progression-free survival compared to […]

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Why Clinical Medical Assistant Certification Improves Healthcare Delivery and Patient Safety

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Most primary care clinics would grind to a halt without clinical medical assistants. They room patients, capture vitals, update histories, handle documentation, coordinate follow-ups, and keep providers from getting buried in the basics. The problem is that the title “medical assistant” doesn’t guarantee the same skill level from one person to the next. Some MAs […]

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Best Three Full-Body Scan Solutions Across the USA

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Weighing scales are typically limited to a single number, which does not give us a comprehensive idea about a person’s physical state. Although a weighing scale may show us weight fluctuations, it does not give us a clear idea about how fat is distributed in a person’s body, how muscles are growing, or how a […]

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You Might Be Obese Despite Your Normal BMI

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Can you be obese with a ‘normal’ BMI? The definition of obese is changing as doctors and health researchers learn more about how our body uses its fat stores. Most of us have heard a story about a skinny uncle who died from heart disease, or a very overweight friend of a friend who ran […]

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FDA approves linerixibat for cholestatic pruritus in PBC

The FDA has approved the first medication for cholestatic pruritus in adult patients with primary biliary cholangitis.
The approval of linerixibat (Lynavoy, GSK) — an ileal bile acid transporter inhibitor that reduces several mediators of pruritus — is first in the U.S. for this indication, according to a manufacturer press release.
The FDA based its decision on the phase 3 GLISTEN trial, which demonstrated significant improvement in cholestatic pruritus at week 2 and up to 24 weeks, as well as improvement in itch-related sleep interference, compared with placebo.
“The approval of linerixibat

GLP-1s increase skeletal risk in patients with diabetes, obesity

NEW ORLEANS — GLP-1 receptor agonist use in adults with concurrent type 2 diabetes and obesity was associated with increased risk for osteoporosis, gout and osteomalacia vs. a matched control group, according to results presented here.
“Losing weight is a good thing. Controlling your diabetes is a good thing,” Joseph A. Abboud, MD, FAAOS, orthopedic surgeon at Rothman Orthopaedics, told Healio about results presented at the American Academy of Orthopaedic Surgeons Annual Meeting. “But understanding that taking that drug under the direct supervision of a physician who

Epioxa epithelium-on cross-linking procedure now available in US

Editor’s note: This is a developing story. Please check back soon for updates.
Epioxa, the first FDA-approved epithelium-on cross-linking procedure, is now commercially available, according to a press release from Glaukos.
The topical therapy offers a streamlined, incision-free treatment for patients with keratoconus, reducing pain associated with epithelium removal and minimizing recovery by using enriched oxygen and light. Epioxa can be ordered from Glaukos or through its specialty pharmaceutical distribution network, according to the release.
Coinciding with the launch, Glaukos announced

Ndemex aims to be ‘part of daily ocular hygiene routine’

ORLANDO — Ndemex, a formulation of tea tree oil designed to promote ocular hygiene, is now available.
It can be used once daily to help “support good ocular health in the fight against blepharitis and other eyelid skin conditions,” Brent Jones, senior vice president of eye care at Hilco Vision, told Healio at Vision Expo.
“We have a very comfortable product that can be used on all skin types, even sensitive skin, to refresh and rejuvenate the area around the eyes,” Jones said. “It’s going to be an affordable option for doctors to recommend as part of your daily ocular hygiene routine.”
Ndemex

‘Striking’ racial disparities in lung cancer treatment persist

The likelihood that a person with early-stage non-small cell lung cancer will receive curative treatment still varies considerably by race, even though 3 decades have passed since researchers first reported the disparity.
An analysis of more than 28,000 Medicare beneficiaries diagnosed with stage I or stage II NSCLC during a recent 15-year period showed white individuals consistently received curative treatment more frequently than Black individuals.
“Disparities in lung cancer treatment within the Medicare population have been documented since the early 1990s. It is pretty striking that, more

FDA approves high-dose Wegovy 7.2 mg for adults with obesity

The FDA approved a higher 7.2 mg dose of injectable semaglutide for adults with overweight and obesity, Novo Nordisk announced.
Once-weekly injectable semaglutide 7.2 mg (Wegovy HD, Novo Nordisk) received accelerated approval based on findings from the STEP UP and STEP UP T2D trials. As Healio previously reported, adults with obesity but without type 2 diabetes receiving semaglutide 7.2 mg in STEP UP lost 20.7% of their body weight at 72 weeks, according to the efficacy estimand. Of the participants receiving semaglutide 7.2 mg, 31.2% lost 25% or more of their body weight at 72 weeks.
In the