A landmark study that started in 2021 to learn about wartime trauma among Vietnamese Americans has received an additional $13.3 in funding to delve deeper into how trauma affects aging and brain health.

For decades, pathologists have diagnosed and graded breast cancer by looking at tissue samples under a microscope, searching for telltale signs of disorder in the structure of cells and tissues. Now, researchers at Columbia and their collaborators have developed a new computational approach that transforms those visual patterns into quantitative measurements, potentially improving how clinicians predict breast cancer outcomes and choose therapies.

A study of more than 1 million women has found that excessive weight gain during pregnancy is linked to an increased risk of potentially life-threatening complications, regardless of whether starting weights were considered underweight, normal, overweight or obese. The study found that the increased risk was between 16% and 33%, and the highest risk was among those considered underweight at the start of their pregnancy.

Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against ovarian cancer in preclinical studies. It's a major development for this type of immunotherapy, which has been used successfully against blood cancers but has so far been less effective in solid tumors.

"Turn off that TV, it'll rot your brain!" has been a household refrain for decades. While "rot" might be too strong a term, researchers are finding that the overall sentiment could have some merit.

Many of the world's leading causes of irreversible blindness, including glaucoma and age-related macular degeneration, share a common problem: the buildup of fluid, waste and inflammatory debris in the back of the eye.

People with Lynch syndrome, the most common hereditary predisposition to colorectal cancer, face a markedly increased cancer risk and therefore undergo regular colonoscopies. Researchers from the University Hospital Bonn (UKB), the University of Bonn, the University of Leipzig, and Amsterdam UMC investigated whether artificial intelligence improves the detection of precancerous lesions. Their findings show that, in specialized centers, AI provided no significant additional benefit. The study was published in The Lancet Gastroenterology & Hepatology.

For decades, medicine has chased a simple but elusive goal of delivering the right drug to the right place at the right time. New research from the University of Oregon suggests that when it comes to healing from injury, the timing of regenerative cues might be even more important than previously realized.

An NSAID-related compound called ampyrone appears to safely boost production of the pigment melanin in human skin, according to a preclinical study led by Weill Cornell Medicine and National Eye Institute investigators. The discovery could lead to the development of an ampyrone-derived treatment for hypopigmentation disorders.

Social connections are known to contribute greatly to people's psychological and emotional well-being. In fact, difficulties socializing and bonding with others have been linked to various psychiatric conditions, including depression, social anxiety disorder (SAD), schizophrenia and post-traumatic stress disorder (PTSD).