Rise of preterm births in US linked to poverty and race

Researchers at Boston Medical Center, working with colleagues at University of Massachusetts Chan Medical School and Harvard T.H. Chan School of Public Health report that US preterm birth rates rose from 2011–2021 in households earning less than 200% of the federal poverty level, while remaining stable among higher-income households. Black mothers had the highest preterm birth rates across all income levels.

International collaboration produces detailed models of the 3D genome over time in cells

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three-dimensional folding of the human genome in human embryonic stem cells and immortalized fibroblasts over time. The result is the most detailed view of the four-dimensional human genome available and the identification of more than 140,000 looping interactions between genes and long-range regulatory elements. The study is published in Nature.

How stress hormone receptors alter the brain and behavior: Zebrafish study provides insights

Stress, the body's natural response to different types of challenges and daily problems, is an inherently harmless state experienced by most people worldwide. While short-term stress is a common experience and can even be beneficial, acute or prolonged stress responses are known to be linked with various neuropsychiatric disorders, including depression and anxiety disorders.