Even with modern biometers, newer IOL formulas and advanced surgical techniques, refractive surprises still occur. Surprisingly, in many cases, the explanation lies not in the technology but in the ocular surface.
Modern cataract surgery has reached remarkable levels of precision. Optical biometers, advanced formulas and refined surgical techniques have made refractive outcomes more predictable than ever before.
Yet refractive surprises still occur.
In everyday practice, surgeons sometimes encounter a familiar situation: postoperative vision that does not match what the preoperative measurements

The FDA has approved an allogeneic regulatory T cell immunotherapy for use in matched-donor hematopoietic stem cell transplantation in patients with blood cancers, to improve survival for chronic graft-versus-host disease.
According to the manufacturer, this newly approved therapy (Tregzi, Orca Bio) is a “personalized treatment manufactured for each individual patient using living cells from a matched donor.” The immunotherapy combines hematopoietic stem and progenitor cells with T cells-vldq and used alongside a myeloablative preparative regimen to support hematopoietic and immune system

PHOENIX — Most patients who used Xiidra eye drops had a “clinically meaningful” reduction in eye dryness by the 84th day of treatment, with some responding within 2 weeks, according to data presented at Optometry’s Meeting.
“Dry eye is a multifactorial disease, and there are a lot of things that contribute to its pathogenesis, meaning that it can be sometimes challenging as clinicians to figure out the right treatments for our patients,” study author Anna A. Tichenor, OD, PhD, FAAO, of the Indiana University School of Optometry, told Healio. “We wanted to specifically look at the data on

The FDA has listed its advisory members for the committee that will discuss peptides in late July.
Owais Durrani, DO, an emergency medicine physician in Houston, previously wrote for Healio that “some of the most transformative drugs in modern medicine are peptides,” including insulin and semaglutide. While “the science of peptides is real, serious and worth pursuing,” Durrani wrote, the current system is messy: “a multi-billion-dollar market, a gray zone of unregulated suppliers, a regulatory system under political pressure, and real people spending real money on compounds that, for most of

The U.S. House Select Committee on China has opened investigations into five pharmaceutical companies regarding their clinical trials in China, questioning whether the drugmakers may have aided the country’s military biotechnology research.
Representatives from AbbVie, Bristol Myers Squibb, Eli Lilly & Co., Merck and Pfizer have until July 17 to answer letters sent to each by committee chairman Rep. John Moolenaar, R-Mich., requesting information detailing due diligence and other standards, including intellectual property and data protection, at clinical trial and manufacturing sites

PARK CITY, Utah — Results presented at the International Extreme Sports Medicine Congress showed implementation of an injury prevention program in mountain bike racing reduced the incidence of injuries.
“If you implement this injury reduction prevention program, you can decrease rates of injuries in youth mountain bikers, and that could be true in a lot of other youth sports, as well,” Aaron Provance, MD, director of pediatric sports medicine at the University of Utah, told Healio.
Provance and colleagues retrospectively reviewed injury surveillance system data from young athletes participating

The Trump administration has proposed what experts are calling “an unprecedented shift” in the way the federal government determines how to distribute grant funding.
The most significant change proposed by the Office of Management and Budget would be a move away from the peer review process to a system that allows political appointees to decide what should be funded. The proposal would also allow federal officials to cancel grant funding at any time.
“The overarching goal,” OMB wrote in its proposal, “is to improve transparency, accountability and oversight for how federal taxpayer dollars are

Upadacitinib improved fistula outcomes in adults with perianal Crohn’s disease, with the strongest benefit reported among those who had no history of tumor necrosis factor inhibition use and those treated earlier in their disease course.
Retrospective cohort study data published in Clinical Gastroenterology and Hepatology showed that 45.5% of patients achieved clinical response and 39.4% achieved clinical remission.
“I don’t recall any prior studies that have shown a relationship between duration of perianal disease in response to this treatment,” Parakkal Deepak, MBBS, MS, co-director of the

Interventions using wearables or smartphones to track daily movement were shown to significantly boost physical activity among patients with a history of heart disease and stroke, researchers reported.
Wearables and smartphones may be accessible options to boost daily steps and moderate to vigorous physical activity among people with CVD and stroke, according to data published in the Journal of the American Heart Association.
“These devices are not just gadgets,” Ramin Zand, MD, MPH, professor of neurology and public health at Penn State College of Medicine, said in a press release. “When

Americans are hearing a confusing message about meat.
Some policymakers and industry voices suggest red meat deserves a central place in a healthy diet, while nutrition experts continue to emphasize moderation and plant-forward eating patterns.
The result is predictable: patients and clinicians are left navigating competing narratives rather than clear guidance grounded in evidence. The real question is not whether red meat belongs in the diet at all, but how much, how often, and in what overall dietary context.
One of the limitations of the current public conversation around red meat is that it