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Neuroscientists have been curious about a link between ketamine and neuroplasticity in treating PTSD and treatment-resistant depression for some time; now they say, they might have discovered some important clues. Researchers based at the Institute of Science and Technology Austria report that ketamine increases neuroplasticity in the brain, but there’s a catch; they only saw […]

The post Ketamine boosts neuroplasticity… but not for everybody appeared first on Medical News Bulletin.

ACOG strengthened its recommendation that OB/GYNs perform salpingectomy during hysterectomy and other surgeries to lower the risk for ovarian cancer.
The latest guidance highlights evidence supporting the removal of both fallopian tubes “as a safe and effective method of reducing patients’ lifetime risk of ovarian cancer,” an ACOG press release said.
“Although advances in treatment have helped patients live longer, mortality from ovarian cancer remains high,” ACOG CEO Sandra E. Brooks, MD, MBA, FACOG, said in the release. “Salpingectomy represents a meaningful opportunity to reduce a person’s

PHOENIX — The odds of cognitive impairment in nursing homes increase with the severity of visual impairment, according to data presented at Optometry’s Meeting.
Researchers from the University of South Florida conducted a cross-sectional analysis of 9,935 nursing home residents aged 65 years and older who were included in the Western North Carolina Nursing Home Study. Based on logMAR visual acuity, residents were categorized as having normal vision, mild or moderate visual impairment, or blindness.
The researchers used a large language model to extract information about their diagnoses and

KIAWAH ISLAND, S.C. — Surgeons who perform corneal allogenic intrastromal ring segment procedures should keep planning simple, according to a speaker at Kiawah Eye & Retina.
In a presentation, Neel R. Desai, MD, shared pearls and what he wished he knew before he started using corneal allogenic intrastromal ring segments (CAIRS) in patients with keratoconus, specifically when placing the ring segments using manual dissection.
“When you conceptually think about dissecting or cross planes with a femtosecond laser, it is indiscriminate with respect to the femtosecond laser plane being a fixed

A kidney transplant recipient with progressive malakoplakia triggered by multidrug-resistant Escherichia coli was successfully treated with a first-in-human engineered bacteriophage cocktail, researchers reported.
Bacteriophages — or phages — are viruses that target and consume bacteria. They have shown promise in recent years as a nontraditional alternative to antibiotics for patients with drug-resistant infections.
The patient treated for malakoplakia in the case report published recently in Clinical Infectious Diseases received a therapy called SNIPR001 (SNIPR Biome), which includes four

An updated clinical guideline is designed to clarify the settings in which radiation therapy is appropriate for pancreatic cancer and outline how the modality can be integrated safely with other treatments.
The guideline — which updates recommendations that American Society for Radiation Oncology (ASTRO) issued in 2019 — address radiation therapy’s role in multiple settings.
“For many years, we haven’t had the prospective evidence necessary to fully demonstrate the impact of radiation therapy in pancreatic cancer,” Daniel Chang, MD, FASTRO, chair of the department of radiation oncology at

A new initiative may help family medicine residents navigate a complicated system to find their perfect match as soon as this year.
In 2025, family medicine welcomed close to 5,400 first-year residents — its largest class of interns — but also left 805 unfilled residency positions, according to the American Academy of Family Physicians. There are more than 800 family medicine programs included in the National Resident Matching Program’s Main Residency Match, which means students can get overwhelmed and struggle to find the right program that fits their interests and values.
So, AAFP launched

The paternal use of valproate, an antiseizure medication, is not associated with neurodevelopmental disorders or congenital malformations in offspring, according to data published in Neurology.
The findings of the birth cohort study suggest that, in instances where valproate is the first-line option or the only effective antiseizure medication (ASM) for a male patient, evidence does not support avoiding its use, said Meng-Han Tsai, MD, PhD, director of the department of medical research at Kaohsiung Chang Gung Memorial Hospital.
“Patients may suffer from inadequate or delayed seizure

HIV immune activity continued in the central nervous system of some adolescents being treated for HIV despite the virus being suppressed in their blood, according to trial data presented at the International AIDS Conference.
The finding, from the Children with HIV Early Antiretroviral Therapy (CHER) trial, has implications for HIV cure research and any study that involves HIV treatment interruption, such as when physicians stop ART after a stem cell transplant to see if a person remains virally suppressed without HIV drugs, which has happened a handful of times over the past several decades.
It

The FDA has granted accelerated approval of a gene therapy to treat children and adults aged at least 8 years with glycogen storage disease type Ia, according to an industry press release.
Pariglasgene brecaparvovec-opnr (Genglycos, Ultragenyx) is the first therapy approved by the FDA to reduce burden of care associated with glycogen storage disease type Ia, according to the company. Glycogen storage disease type Ia is a rare genetic metabolic disorder in which a deficiency of the glucose-6-phosphatase enzyme prevents the liver from controlling glucose levels. The disorder requires close