What Makes a Supplier Reliable in the Research Materials Market

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

For scientists and laboratory professionals buying research materials is a deal. What you put into an experiment directly impacts the results. In a market where many suppliers say they offer top-notch compounds it’s crucial to know how to find sources. You need to be able to tell the difference between unreliable suppliers. Every researcher needs […]

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Genetic Testing Can Help Docs Choose Personalised Treatment for Depression

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

The age of personalized medicine is fast approaching, and with it, a whole new strategy for prescribing antidepressants. Researchers report in the medical journal JAMA Network Open that they are on the way to cracking the code to prescribe our best course of Selective Serotonin Re-uptake Inhibitor (SSRI) to treat moderate depression based on our […]

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Essilor Stellest lenses show myopia-slowing effect for 7 years

DENVER — Essilor Stellest lenses slowed myopia progression by more than 2 D and reduced axial length growth by nearly 1 mm over 7 years of wear, according to data shown at the Association for Research in Vision and Ophthalmology meeting.
This is the only spectacle lens currently authorized in the U.S. for the slowing of pediatric myopia.
“What makes these findings particularly important is the duration of follow-up,” Björn Drobe, PhD, director, applied myopia research, EssilorLuxottica, told Healio. “Seven-year data provide valuable insight into treatment outcomes over time.”

Smoking, physical inactivity associated with cancer-related pain

CHICAGO — Smoking and limited physical activity were significantly associated with poor pain outcomes among cancer survivors, according to results of a cross-sectional analysis.
The data, presented at ASCO Annual Meeting, showed that individuals who never smoked or are former smokers had a significantly lower likelihood of reporting uncontrolled pain than current smokers. Similarly, individuals who did not engage in physical activity had 72% greater odds of experiencing cancer-related pain than those who exercised.
“This is huge,” Clifford A. Atuiri, MD, MPH, CPH, resident physician at St.

Patient resilience may not affect outcomes after ACL reconstruction

PHOENIX — Preoperative level of patient resilience did not affect pain and quality of life scores after ACL reconstruction, according to results presented here.
“Our a priori hypothesis was patient resilience affects clinical outcomes after ACL reconstruction as represented in knee pain, knee quality of life and then in subsets of ACL injury specific patient-reported outcomes,” Andrew J. Sheean, MD, of the University of Wisconsin, told Healio. “Interestingly, we found that resilience does not appear to affect knee pain and knee related quality of life at 1 year after ACL reconstruction.”

Oculis DME eye drop fails to meet primary endpoint

Oculis will not pursue FDA approval for OCS-01, an eye drop for diabetic macular edema, after it failed to meet the primary endpoint in a phase 3 program, according to a press release.
The DIAMOND program included two phase 3 trials that evaluated OCS-01 (dexamethasone 15 mg/mL) in more than 800 patients with DME. Both trials, DIAMOND-1 and DIAMOND-2, failed to meet their primary endpoint of mean change in best corrected visual acuity from baseline to week 52, according to the release.
Both trials showed improvement in retinal thickness measured by OCT, a secondary endpoint of the program,

Eye care needs to consider use of paper, plastic, metal materials

Click here to read the Healio Exclusive, “EyeSustain, industry collaborate to reduce waste.”
Eye care practices and especially eye surgery centers are important contributors to paper, plastic and even metal pollution.
Eye care has a significant carbon footprint, which is a factor in climate change, an existential threat to us all. Potential achievable solutions include decreasing the unnecessary excess paper and plastic associated with medical product packaging, increasing reusable medical products and recycling medical product waste. I recently wrote a perspective on the efforts of EyeSustain

FDA approves Zaynich for complicated UTIs

The FDA approved Zaynich as an intravenous treatment for complicated urinary tract infections, including pyelonephritis, in adults, according to a press release from the antibiotic’s manufacturer, Wockhardt.
“The threat of drug-resistant infections is an escalating crisis, leaving clinicians with fewer tools to treat patients facing these aggressive pathogens. The FDA approval of Zaynich is a monumental step forward in validating a new option for these underserved populations,” Wockhardt Chief Medical Officer Dennis Deruelle, MD, FHM, said in the release. “This milestone underscores our

Repurposed treatments show promise for cutaneous vasculitis

CLEVELAND — Researchers are uncovering triggers and treatments for cutaneous vasculitis, an inflammatory condition that damages the skin’s blood vessels, according to a speaker at Cleveland Clinic’s Medical Dermatology Therapy Update IV.
“About 80% percent of patients who present with cutaneous small vessel vasculitis or vasculitis in the skin have skin-limited disease,” Evan Piette, MD, director of the cutaneous vasculitis clinic at Brigham and Women’s Hospital, told Healio. “About 12% have systemic IgA vasculitis, and around 8% have another systemic vasculitis or connective tissue disease.”

Buprenorphine lowers suicidality after ketamine treatment

Low-dose buprenorphine given after a single treatment of ketamine reduced suicidal ideation by 76% in adults with major depressive disorder, findings show.
The encouraging data come during a severe mental health crisis in the U.S., as “about 13 million people seriously consider suicide annually,” study co-author Alan F. Schatzberg, MD, the Kenneth T. Norris Jr. Professor in Psychiatry and Behavioral Sciences at Stanford University, said during a press briefing. “We have about 4 million with actual plans. A million and a half adults attempted suicide, some had multiple suicide attempts.... This