‘BMI does not tell the whole story in MASLD’; body roundness might

NASHVILLE, Tenn. — Body roundness index may improve mortality risk stratification in metabolic dysfunction-associated steatotic liver disease, identifying high-risk lean and nonobese individuals often overlooked by BMI.
Findings presented at ACG Annual Scientific Meeting indicated that, although BMI remains a useful measure of overall body size and obesity, complementing with body roundness index may help capture body shape and central adiposity risk factors that BMI alone may miss.
“We often use BMI as a shorthand for obesity and metabolic risk, yet we see patients with MASLD who have a normal

Medication safety in obesity care: Looking beyond the prescription

As obesity medications continue to transform care, selecting the right one requires more than meeting BMI criteria.
From choosing the most appropriate medication to managing adverse effects and monitoring long-term health outcomes, it is crucial for clinicians to take a comprehensive and individualized approach to treatment.
BMI tells us who qualifies for treatment. Biology tells us which treatment is most likely to succeed.
One of the biggest shifts in obesity medicine over the past decade is that we’ve stopped asking, “Does this patient qualify for medication?” and started asking, “What is

FDA clears twiist for adults with type 2 diabetes

The FDA has cleared an automated insulin delivery system for adults with type 2 diabetes who are treated with insulin, according to an industry press release.
As Healio previously reported, the system (twiist, Sequel Med Tech) was cleared by the FDA in March 2024 for children and adults aged 6 years and older with type 1 diabetes. The FDA’s newest clearance expanded the system’s indication to include adults aged 18 years and older with type 2 diabetes.
The FDA’s clearance followed findings from a 13-week multicenter trial of 307 adults. As Healio previously reported at the American Diabetes

Key takeaways from updated thyroid disease in pregnancy guideline

An updated guideline proposed several shifts in how healthcare professionals manage thyroid health for pregnant women.
In May, the American Thyroid Association published its newest guideline for thyroid disease in preconception, pregnancy and postpartum in the journal Thyroid. The first update of the guideline since 2017 recommends changes in care and an increased emphasis on shared decision-making between patients and healthcare professionals, according to Angela M. Leung, MD, MSc, professor of medicine at the UCLA David Geffen School of Medicine and co-first author on the guideline.
“More

ADHD linked to higher risk for cognitive impairment, dementia

Among people aged 50 years and older, ADHD was associated with a more than four-fold higher risk for cognitive impairment, according to research published in JAMA Psychiatry.
Individuals with ADHD who developed cognitive impairment also reported poorer mental health, quality of life and social satisfaction, which suggests broader implications for overall well-being, said Douglas Teixeira Leffa, MD, PhD, a psychiatrist and former resident with the University of Pittsburgh Medical Center, where the research was conducted.
“As people with ADHD age, clinicians should also be attentive to meaningful

Telikibart shows ‘promising efficacy’ for moderate to severe eczema

Telikibart demonstrated promising efficacy in the treatment of adults with moderate to severe atopic dermatitis, according to a presentation at the European Academy of Dermatology and Venerology Congress.
Telikibart (GR1802, Genrix) is a fully human monoclonal antibody that suppresses type 2-driven inflammation by inhibiting interleukin-4 and -13.
“AD is one of the most widespread diseases in the world,” Shangshang Wang, MD, PhD, associate chief physician in the department of dermatology at Huashan Hospital, Fudan University in Shanghai, said during the presentation. “AD is characterized by

High genetic CAD risk score elevates odds for repeat revascularization

In patients who underwent coronary revascularization, those with a high risk score for coronary artery disease had elevated odds of repeat revascularization or CV death compared with those with a low score, researchers reported.
“Even after successful coronary revascularization, patients with severe CAD remain at risk for recurrent events and repeat procedures,” Arman Qamar, MD, MPH, director of the Center for Cardiovascular Personalized Medicine in the section of interventional cardiology at Endeavor Health in Glenview, Illinois, told Healio. “We wanted to determine whether inherited genetic

Nothing ties psychiatry’s digital tools together

Every year, the behavioral health industry gathers at Behavioral Health Tech, one of the largest meetings of its kind.
It is the place where the payers, the health systems, the startups and the investors who will decide what our field’s infrastructure looks like all end up in the same exhibit hall. This year it was in Nashville, Tenn.
I spent 2 days on the floor, and I came home with a feeling I had not expected. Not excitement. Something closer to vertigo.
Every booth had something real. A scribe that listens to the visit and writes the note, so the doctor can stop typing and look at the

Infection rates more frequent in home vs. in-center hemodialysis

Vascular access-related infections occurred more frequently among patients using home hemodialysis vs. in-center hemodialysis, according to study data published in the Journal of the American Society of Nephrology. 
Home hemodialysis use has increased in the United States, but concerns have been raised about risks for vascular access-related infections at home compared with in-center hemodialysis, according to Jeffrey Perl, MD, FRCP(C), SM, staff nephrologist at St. Michael’s Hospital in Toronto, and colleagues, including Brian Bieber, MS, MPH, research scientist in data science at Arbor

Consensus paper calls for universal type 1 diabetes screening

A new consensus guideline advocates for healthcare systems to conduct general population screening for type 1 diabetes.
In an article published in Diabetologia, an international group of experts detailed recommendations for conducting general population screening for type 1 diabetes islet autoantibodies to diagnose early-stage disease. The report, which was endorsed by 20 diabetes organizations from around the world, detailed the age and frequency at which screening should take place, how healthcare professionals should discuss screening and results with families and the steps countries should