PHILADELPHIA — Wide gaps exist in the prevalence, awareness and treatment of many cardiometabolic conditions, and policies that expand access and lower drug costs will be key to reducing the burden of disease in the U.S., a speaker said.
At the Heart in Diabetes CME Conference, Rishi K. Wadhera, MD, MPP, MPhil, cardiologist at Beth Israel Deaconess Medical Center, discussed gaps in the “cardiometabolic care cascade” and recent policies that both narrowed and widened that gap.
“One of the great public health successes in the U.S. has been the decline in cardiovascular mortality that we’ve

AGA’s recent white paper provides a framework to navigate the latest innovations in obesity care, including GLP-1 receptor agonists, personalized treatment plans and endoscopic, bariatric and metabolic therapies.
The new commentary is a follow up to AGA’s 2017 publication, “POWER: Practice Guide on Obesity and Weight Management, Education, and Resources,” and encourages gastroenterologists to take initiative in treating the disease in their daily practice.
“Now more than ever, gastroenterologists need to embrace treating obesity,” lead author Andres J. Acosta, MD, PhD, professor of medicine and

The FDA approved Zoryve cream 0.3% for the treatment of plaque psoriasis in children as young as 2 years, Arcutis announced in a press release.
Roflumilast (Zoryve, Arcutis) cream 0.3%, a phosphodiesterase-4 inhibitor, is already FDA-approved for children 6 years and older. The expanded indication gives caregivers a once-daily, steroid-free topical for younger children with psoriasis, including in intertriginous areas, according to the release.
This approval marks a step forward for pediatric patients with psoriasis, who have been limited to using topical corticosteroids for years, according to

Pregnancy for living kidney donors may be associated with increased risks for infants with low birth weight or small for gestational age, according to data published in Nephrology Dialysis Transplantation.
About 60% of living kidney donors internationally are women, many of whom are of reproductive age, according to Eva Carlsson, a researcher in the department of medical sciences at Uppsala University, Sweden, and colleagues. However, the association between living kidney donation and pregnancy outcomes has not been well-established in research, the researchers wrote.
“Our aim was to strengthen

A 70-year-old woman presents to the ED with chest pain, shortness of breath and diaphoresis. Her symptoms began about 24 hours ago during her husband’s funeral. They were married for 45 years.
He died tragically in a motor vehicle crash. The patient was devastated and barely functional after the sudden loss. Fortunately, her twin sister handled most of the funeral arrangements.
Shortly after the funeral, the patient’s sister noted she didn’t look well, so she took her to the ED for evaluation.
In the ED, the patient was escorted directly to the cardiac room. The physician saw her right away. The

Some repeated low-level red light therapy devices for myopia control may not meet safety standards for lasers and ophthalmic lights, according to data published in JAMA Ophthalmology.
“Given the impressive clinical reports in controlling myopia in children, we were excited to try red laser therapy ourselves,” study co-author Lisa Ostrin, OD, PhD, FAAO, FARVO, associate professor at the University of Houston College of Optometry, told Healio. “However, in examining a few commercial devices, we simply observed that the power was much higher than expected. This prompted our systematic evaluation

NEW ORLEANS — Even with all the advances in technology, Diana Isaacs, PharmD, BCPS, BCACP, BC-ADM, CDCES, FADCES, FCCP, said patients remain at the center of diabetes management.
Isaacs, an endocrine clinical pharmacy specialist at Cleveland Clinic and a Healio | Endocrine Today Editorial Board Member, said during her career she has seen diabetes technology such as continuous glucose monitoring go from a niche concept to standard of care for people with diabetes, and expects technology will advance even quicker as time goes on. Despite this, Isaacs said, diabetes technology and AI cannot

CHICAGO — In this video, Sara A. Hurvitz, MD, FACP, discusses the ASCENT-03 study, which showed treatment with sacituzumab govitecan improved PFS and delayed subsequent therapy vs. chemotherapy in metastatic triple-negative breast cancer.
Results of the trial, which compared sacituzumab govitecan (Trodelvy, Gilead Sciences) with chemotherapy in previously untreated patients who were ineligible for PD-L1 inhibitors, were presented at ASCO Annual Meeting.
“Despite this high rate of crossover from chemo to sacituzumab, we also demonstrated that the time to first subsequent therapy and

It has been nearly 9 months since the first documented alpha-gal syndrome fatality from mammalian meat consumption was reported in The Journal of Allergy and Clinical Immunology: In Practice.
Within the past year, tick populations have expanded, more states are requiring alpha-gal syndrome (AGS) reporting and research on onset to diagnosis timing has been published, according to Gary Falcetano, PA-C, AE-C, senior manager of global medical and scientific affairs for allergy/ImmunoDiagnostics at Thermo Fisher Scientific.
Healio spoke with Falcetano to learn more about these and other changes in

When people ask how I ended up in rheumatology, I always find it difficult to point to a single moment or a single person.
In my case, the path was shaped by a series of mentors, each of whom influenced a different aspect of how I think about science, medicine and patient care.
My first exposure to immunology came before medical school, when I worked at the NIH in the dermatology branch of the National Cancer Institute. There, I had the opportunity to work closely with Wolfgang Leitner, DSc, MSc, who is now chief of the innate immunity section at the National Institute of Allergy and Infectious