Self-acupressure significantly reduces fatigue in ovarian cancer

A self-acupressure app helped nearly 60% of women with ovarian cancer no longer experience cancer-related fatigue.
The MeTime app, which teaches individuals how to perform self-acupressure, significantly decreased fatigue and improved quality of life among participants compared with usual care.
“Self-acupressure is a simple, safe and inexpensive way to decrease cancer fatigue,” Suzanna M. Zick, ND, MPH, professor in the department of family medicine at Michigan Medicine and Nutritional Sciences in the School of Public Health, told Healio. “This is a free treatment.”
Approximately 250,000 women

Q&A: New guidance on obesity drugs can ‘reframe the delivery of care’

Experts from leading obesity organizations have published recommendations affirming the effectiveness, safety and appropriateness of weight-loss drugs for long-term use.
According to a press release, new joint guidance from The Obesity Society, the Obesity Medicine Association and the Obesity Action Coalition “reinforce obesity as a chronic disease and emphasize that medications can play a critical role in improving both health and quality of life.”
The guidance, published in Obesity Pillars and Obesity, gives strong recommendations for several drugs, including semaglutide

Exercise presents opportunity to improve outcomes in CKD

Chronic kidney disease affects millions of individuals worldwide and is frequently accompanied by profound declines in physical function, muscle mass and overall quality of life.
Fatigue, reduced exercise tolerance and progressive muscle wasting are common across all stages of CKD and contribute to increased frailty, hospitalization and mortality. Historically, these complications were often viewed as unavoidable consequences of kidney disease.
However, a growing body of research now demonstrates that physical activity and structured exercise programs can significantly improve health outcomes

Home phototherapy cost-effective option for psoriasis, yet remains underused

Adults with moderate to severe plaque psoriasis saw the greatest mean quality-of-life gains with biologic therapy whereas home phototherapy offered lower costs for patients and payers, according to a study published in JAMA Dermatology.
Phototherapy is an effective and cost-effective treatment for people with psoriasis across all skin types; however, its use has been limited by insurance coverage policies and the inconvenience of in-office treatment, Edward L. Kong, PhD, an eighth-year MD/PhD student at Harvard Medical School and the Harvard Department of Economics, and Elizabeth A. Buzney,

Pilot program improves blood pressure in Black communities

A novel pilot program led by community health workers, tying in virtual health interventions, improved BP control in more than half of participants living in Indianapolis anchor communities, researchers reported.
The CHECK-IT program incorporated an in-person visit from a community health worker to deliver a free BP cuff and train participants how to use it. The worker also provided social support, assessed social determinants of health needs and connected participants with other resources if necessary. Via a smartphone app (Twistle), participants provided their home BP readings and received

Patients with GA require careful screening, opportunity for treatment

Click here to read the Cover Story “Specialists navigate changing, challenging landscape of geographic atrophy management.”
More knowledge about the diagnosis and management of geographic atrophy is important for every eye doctor.
We now have two FDA-approved drugs using intravitreal injection of complement inhibitors, Syfovre (pegcetacoplan injection, Apellis) and Izervay (avacincaptad pegol intravitreal solution, Astellas), that can delay progression of the disease. In the following paragraphs, I will share a few insights that I hope will be useful to the comprehensive ophthalmologist.
Dry

Ozempic tied to cardiometabolic benefits, may lower CVD risk in type 1 diabetes

Once-weekly semaglutide 1 mg improved multiple cardiometabolic measures in patients with type 1 diabetes and may reduce long-term cardiovascular disease risk, according to a presenter.
As Healio previously reported, in the ADJUST-T1D study, researchers found semaglutide 1 mg (Ozempic, Novo Nordisk) provided greater glycemic benefits and body weight loss for adults with type 1 diabetes and obesity compared with placebo. In new data from the trial presented at the International Conference on Advanced Technologies & Treatments for Diabetes, semaglutide was also tied to greater improvements in

Wearable sensors spot activity changes that precede disability progression in MS

Decreases in daytime activity among adults with MS, indicated via accelerometers worn on their wrists, indicated later development of worse disability and brain atrophy, according to data published in Neurology.
Changes in circadian rhythm patterns preceded worse disability and brain atrophy as well, Kathryn C. Fitzgerald, ScD, ScM, assistant professor, division of neuroimmunology and neurological infections, department of neurology, Johns Hopkins School of Medicine, and colleagues wrote.
“Current tools used to measure disability progression in multiple sclerosis, such as the Expanded

Reduced COPD exacerbation risk with dry powder inhaler

New long-acting muscarinic antagonist-long-acting beta agonist users had a decreased risk for a first moderate/severe COPD exacerbation with a dry powder inhaler vs. a metered-dose or soft mist inhaler, according to study results.
These data were published in JAMA Internal Medicine.
“We have now seen across two studies that once-daily dry powder inhalers seem to be associated with slightly improved clinical outcomes compared to twice-daily metered dose inhalers,” William B. Feldman, MD, DPhil, MPH, associate professor of medicine at the David Geffen School of Medicine at UCLA, director of

Verekitug shows promise as CRSwNP treatment in phase 2 trial

PHILADELPHIA — Among adults with chronic rhinosinusitis with nasal polyps, those receiving verekitug vs. placebo at baseline and week 12 had significantly decreased nasal polyp size at week 24, according to a poster presented here.
These data on verekitug (Upstream Bio), a novel, fully human monoclonal antibody antagonist of the thymic stromal lymphopoietin (TSLP) receptor, were presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
“These data should add to the enthusiasm about the potential for a longer interval, highly effective drug in CRSwNP,” Aaron Deykin,