Young women with a prior diagnosis of cervical high-grade squamous intraepithelial lesion may experience increased risk for heart disease, particularly heart attack, heart failure and cerebrovascular disease, researchers reported.
Adolescents and young women with a history of cervical high-grade squamous intraepithelial lesion (HSIL) also experienced higher prevalence of chronic obstructive pulmonary disease (COPD), smoking and family history of CVD compared with matched controls, according to a study.
Research evaluating CV risk among adolescents and young women with a history of cervical

The FDA has approved deucravacitinib for adults with active psoriatic arthritis, according to a press release from Bristol Myers Squibb.
Deucravacitinib (Sotyktu), an oral, selective tyrosine kinase 2 (TYK2) inhibitor has already received FDA approval for adults with moderate-to-severe plaque psoriasis.
“We welcome the addition of deucravacitinib to our PsA treatment armamentarium,” Philip J. Mease, MD, of the Swedish Medical Center and the University of Washington, told Healio. “Sotyktu is an effective oral treatment option which fulfills an unmet need both for patients who

Asking caregivers if they are concerned about clutter or possible hoarding may help identify neurocognitive disorders, according to a study published in The Journal of Neuropsychiatry and Clinical Neurosciences.
Led by Peter Pressman, MD, associate professor of neurology at Oregon Health & Science University, the researchers defined hoarding disorder as a “persistent difficulty discarding or parting with possessions, regardless of their actual value.”
“Our team suspected that hoarding was more common in behavioral neurology clinics than many people were catching. Many

Obesity and type 2 diabetes are deeply interconnected. Yet, many diabetes prevention programs fail to adequately treat obesity as the chronic, relapsing disease that it is.
While lifestyle interventions remain foundational, decades of evidence and newer therapies have made it clear that obesity treatment is one of the most effective ways to prevent type 2 diabetes.
To achieve more meaningful, sustained reductions in diabetes risk, it is important to rethink how prevention programs are designed. That means going beyond coaching alone and building in medical, behavioral and surgical tools that

In veterans with type 2 diabetes, treatment with GLP-1 receptor agonists was associated with a reduced risk for various substance use disorders compared with sodium-glucose cotransporter-2, or SGLT-2, inhibitors, data show.
Researchers also noted that GLP-1s appeared to lower the risk for adverse outcomes among participants with preexisting substance use disorders (SUDs), “suggesting potential utility of GLP-1 receptor agonists in the treatment of SUDs,” researchers wrote in The BMJ.
“GLP-1 drugs appear to have broad anti-addictive properties. They are not working on one substance, but across

PHILADELPHIA — Children with food allergy who used omalizumab plus oral immunotherapy vs. omalizumab alone had similar rates of allergen consumption a year after treatment, according to published data.
R. Sharon Chinthrajah, MD, FAAAAI, professor of pediatric food allergy, immunology and asthma at Stanford University, presented these phase 3 findings from the OUtMATCH study at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
“Really, there’s no difference in the ability to introduce foods into the diet, which is great,” Chinthrajah told Healio. “You can be on

Thirty-day mortality of patients with major trauma fell if they received intubation before hospital admission per prediction from a machine learning risk-stratifying model, according to data published in The Lancet Respiratory Medicine.
“This is, to our knowledge, the highest level of evidence to date on prehospital intubation efficacy in major trauma and could inform policy discussions on funding specialist prehospital critical care teams to consider improving access to this intervention,” Amy PK Nelson, MBChB, NIHR academic clinical fellow at King’s College London and PhD candidate at

New ASH guidelines outline optimal management for a subgroup of patients with leukemia that historically has been challenging to treat.
Two papers published simultaneously in Blood Advances address best practices for treatment of adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
One guideline focuses on frontline treatment. The other focuses on relapsed or refractory disease.
“This is a unique group of patients with different needs, so these guidelines are very important — especially for clinicians who practice outside of academic centers and perhaps don’t see as much ALL,”

Expansion of Medicaid eligibility was linked to a modestly higher prevalence of colorectal cancer screening among Latino men and Latina women, a case-control study in JAMA Network Open revealed.
“Latino men, in particular, have exhibited a notably low prevalence of completing colorectal cancer screenings, highlighting a critical area for intervention,” Nathalie Huguet, PhD, the study’s lead author and associate professor of family medicine at Oregon Health & Science University, told Healio. “Health care professionals should prioritize identifying strategies that can effectively increase

Dual therapy with a GLP-1 receptor agonist plus ixekizumab demonstrates long-term benefits in psoriatic disease activity, according to data presented at the Basic and Clinical Immunology for the Busy Clinician symposium.
“Psoriatic arthritis seems to have a special place for increased risk for obesity,” said Philip J. Mease, MD, of the Swedish Medical Center and the University of Washington.
During the meeting, Mease highlighted data showing 48% of patients with PsA are obese or overweight.
“This number is climbing,” he said, adding that it is likely to surpass 50% in the