Study of 2 million newborns ties skipped vitamin K shot to higher bleeding risk

Newborns receive several routine immunizations shortly after birth. Prophylactic vitamin K is one such recommended shot. It activates several coagulation factors necessary for blood to clot properly, preventing vitamin K deficiency bleeding (VKDB), a condition that can be life-threatening. As more parents refuse prophylactic vitamin K for their children, researchers in Sweden wanted to examine trends in newborn vitamin K shots over time and any associations with infant bleeding diagnoses.

Ivermectin taken at the start of pregnancy is not associated with an increased risk of adverse pregnancy outcomes

A study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by the "la Caixa" Foundation, found no increased risk of miscarriage, stillbirth or major congenital anomalies among women inadvertently exposed to ivermectin from two weeks before conception through the first four weeks of pregnancy. The findings, published in eClinicalMedicine, add to the available evidence on the safety of this antiparasitic drug during the very early stages of pregnancy, although the researchers stress that the number of cases remains too small to warrant changes to current recommendations.

Rat study finds early secondhand smoke exposure can alter tooth enamel mineralization

Exposure to secondhand cigarette smoke during the first days of life can cause changes in tooth enamel mineralization without causing visible changes to the teeth. This was demonstrated in an animal model study conducted by researchers at the Ribeirão Preto School of Dentistry at the University of São Paulo (FORP-USP) in Brazil. The results were published in May in the scientific journal Calcified Tissue International.

Bulletin: Portable Air Purifiers in Elder Care Homes Don’t Prevent Respiratory Infections

NASS releases guidelines for use of antithrombotic therapies

The North American Spine Society has released evidence-based clinical guidelines and appropriate use criteria for antithrombotic therapies in adults undergoing spine surgery, according to a press release.
“These are very useful documents. They are reasonably concise, comprehensive and up to date. They are not meant to represent standard of care, nor do they replace provider judgment and experience along with patient values. However, they can assist in decision making in a very meaningful way. Where the evidence is robust either for or against an intervention, those recommendations should