Businesses continue to sell compounded semaglutide, tirzepatide

Compounded forms of semaglutide and tirzepatide were being sold by dozens of compounded pharmacies from August to October 2025, months after the FDA declared an end to compounding for those drugs, researchers reported.
As Healio previously reported, the FDA removed tirzepatide (Mounjaro/Zepbound, Eli Lilly) from its drug shortage list in December 2024 and semaglutide from its drug shortage list in February 2025. The FDA prohibited the distribution of compounded forms of the drugs after May 22, 2025. However, a “secret shopper” study published in JAMA Health Forum identified 75 businesses in

Peptide eye drop reduces fluid, thickness in wet AMD

CG-P5, a topical peptide eye drop, met safety and efficacy endpoints for wet age-related macular degeneration, according to a presentation at the American Society of Retina Specialists annual meeting.
“When we start thinking about the current demand and what we actually need for patients with wet macular degeneration, there’s a clear need for up to 40% of patients who don’t have full optimal treatment,” David Almeida, MD, MBA, PhD, of Erie Retina Research in Pennsylvania, told Healio. “What do we do with those patients? This is where I think this phase 1 study really becomes interesting and

Q&A: How to avoid missing a case of pediatric malaria

More than one-quarter of children in the United States diagnosed with malaria in the past decade had a delayed diagnosis because they were not tested during their first health care encounter after the onset of symptoms, researchers found.
According to the CDC, approximately 2,000 cases of malaria are reported in the U.S. each year, most among people who traveled to or recently immigrated from countries where the mosquito-borne disease is endemic. Local transmission in the U.S. can occur — there were 10 cases in 2023 — but it is rare.
Sesh A. Sundararaman, MD, PhD, a pediatric infectious disease

Telehealth can safely reduce travel in pediatric cancer

Telehealth could substantially reduce travel burdens for children and adolescents with cancer undergoing intensive chemotherapy without significantly impacting safety.
A randomized trial in Germany showed that patients receiving virtual follow-up care saved more than 40,000 km combined, and they had similar rates of grade 3 or worse adverse events compared with those treated in-person.
“This study argues for implementation of telemedicine in routine patient care even during intensive chemotherapy — which may ease life for patients, families and for hospitals,” Denis M. Schewe, MD, professor and

Robust growth seen with potential first hair loss pill for women: Topline data

A proprietary extended-release oral minoxidil tablet induced rapid, robust and consistent hair growth in women with female pattern hair loss, according to topline results.
Results from study 207 showed VDPHL01 (Veradermics) increased hair count for women who received once or twice daily dosing for 6 months and was generally well tolerated with no evidence of serious adverse events, including cardiac events of special interest, according to a company press release. If approved, this pill would be the first oral treatment indicated for female pattern hair loss.
“Female pattern hair loss has long

Voting is open! Choose this year’s Disruptive Innovators in gastroenterology, hepatology

Healio Gastroenterology is excited to announce the nominees for its annual Disruptive Innovators Awards in gastroenterology and hepatology.
Individuals who changed the face of the specialty and pushed the status quo toward betterment of the field will be recognized during a live event at ACG Annual Meeting Oct. 9-14 in Nashville.
In this video, awards ceremony cohosts Edward V. Loftus Jr., MD, chief medical editor of Healio Gastroenterology, and Ugo Iroku, MD, MHS, cofounder of the Association of Black Gastroenterologists and Hepatologists (ABGH), are joined by Amrita Sethi, MD, founder and

Variation in cardiology services pricing by insurer

Variation in facility fees was linked to significant differences in cost of cardiology services with major national insurers, according to a study published in JAMA Network Open.
Facility fees varied by nearly $30,000 for certain cardiology procedures, with UnitedHealthcare and Blue Cross Blue Shield having the highest facility prices and Aetna consistently having the lowest, researchers reported.
“In 2023, implementation of Hospital Price Transparency and Transparency in Coverage (TIC) rules mandated insurers to publicly disclose negotiated rates for health care services. These policies aim to

FDA approves subcutaneous Leqembi for initiation

The FDA has approved a subcutaneous dose for initiation of lecanemab treatment in adults with Alzheimer’s disease, according to a press release from the administration.
Previously, patients had to begin treatment with an intravenous dose.
Researchers conducting a real-world study, presented at the Alzheimer’s Association International Conference, found that most patients remained stable over an average of 17 months on intravenous and subcutaneous doses of lecanemab (Leqembi; Eisai).
“For the first time, patients and their care partners have a choice in how anti-amyloid treatment is delivered,”

Whole blood, blood components prehospital transfusion similar

ORLANDO — Thirty-day mortality of injured patients with hemorrhagic shock did not differ based on use of whole blood vs. blood components in prehospital transfusion, according to results presented here.
In addition to being presented at the American Thoracic Society International Conference, these findings were simultaneously published in The New England Journal of Medicine.
“In injured patients requiring prehospital blood transfusion at risk of hemorrhagic shock, whole blood did not result in a lower 30-day mortality,” Jason L. Sperry, MD, MPH, Andrew B. Peitzman Professor of Surgery at the

High EoE prevalence found via screening in pediatric asthma

Through a symptom-based screening approach, 8% to 13.9% of pediatric patients with asthma who were seen in an academic pediatric asthma/allergy clinic had eosinophilic esophagitis, according to study results.
These results were published in The Journal of Allergy and Clinical Immunology: In Practice.
“These findings highlight that EoE is not an uncommon problem for children with asthma, and there may be a role for screening children with asthma for symptoms of EoE proactively,” Robert E. Becker, MD, pediatric gastroenterologist at Children’s Hospital of Wisconsin and assistant professor of