NEW ORLEANS — In this video from the National Kidney Foundation Spring Clinical Meetings, Paolo Cravedi, MD, PhD, discusses the treatment landscape in complement 3 glomerulopathy.
Cravedi, professor in the division of nephrology at the Icahn School of Medicine at Mount Sinai, highlights the effectiveness of new treatments for complement 3 glomerulopathy in both transplant and native cases.
“The challenge is how to use these treatments, for how long, [and] whether should we use them to prevent the disease recurrence in the transplant or after the disease has recurred,” Cravedi

Viewers of outpatient dermatology clinic notes vary widely by race, sex and economic background, suggesting that broader access issues may impact electronic patient portal engagement, according to data published in JAMA Dermatology.
“Patients in the U.S. have had access to electronic clinical notes since 2021, when provisions of the 21st Century Cures Act, mandating immediate patient access to electronic clinical notes, took effect,” Connie Shi, MD, FAAD, assistant professor of dermatology at Harvard Medical School and Brigham and Women’s Hospital, told Healio. “However, until this study,

Firearm deaths decreased by 5% from 2023 to 2024 in the U.S., although such mortalities remain high, with one occurring every 12 minutes, a report from the Johns Hopkins Center for Gun Violence Solutions shows.
Rose Kim, MPA, an assistant policy advisor at Johns Hopkins Bloomberg School of Public Health, told Healio that the decrease is encouraging but “nearly 45,000 Americans died of firearm injuries, which was the fifth highest total ever recorded. While overall firearm deaths and firearm homicides have decreased since 2021, overall firearm deaths remain well above pre-pandemic levels due to

One in five adolescents and young adults in the United States reported using AI chatbots for mental health support in 2025, and most did not tell anyone, according to a recent survey study.
AI chatbots are growing in popularity, and many people are beginning to use them for mental health support. Recent data show that chatbots may reduce stigma around mental health conditions, although experts caution that AI tools should not replace professional mental health care.
“These tools may be appealing because they are available at any hour, feel private and can provide immediate responses at a time

Alcohol consumption and smoking were identified as the two strongest common risk factors for breast cancer and atrial fibrillation globally, according to data published in the Journal of the American Heart Association.
Reducing alcohol intake and smoking behaviors to the level at which risk is smallest, nearly one-third of breast cancer cases and 12% of AF cases could be prevented, the researchers wrote.
“One of the most surprising aspects of our findings was how common both breast cancer and atrial fibrillation/flutter diagnoses were among women ages 55 and older in high-income regions,

Patients with very early or early-stage hepatocellular carcinoma have similar survival with external beam radiation as they do with traditional therapies.
A systemic review of approximately 5,000 patients with HCC showed those with Barcelona Clinic Liver Cancer (BCLC) stage 0 had a median OS of nearly 7 years and those with stage A disease had a median OS of almost 5 years.
The “benchmark” for traditional therapies, such as ablation, resection and transplant, is 5 years or more, Andrew M. Moon, MD, MPH, assistant professor of medicine in the division of gastroenterology and hepatology at The

Recently I saw a patient with Down syndrome on whom I had performed bilateral corneal cross-linking 5 years ago.
This young woman, now 28 years old, is engaged to be married, works in a bridal shop and has been enjoying increasing independence. She has a zest for life that I know could so easily have been compromised or limited by visual impairment if we had not caught her keratoconus and treated it early.
There is a high prevalence of keratoconus in people with trisomy 21, or Down syndrome. Keratoconus can progress more rapidly and present more severely in this population, so we want to treat

CHICAGO — In a cohort of patients with difficult-to-control type 2 diabetes, more than 75% had elevated cortisol at a level that has been associated with an elevated prevalence of cardiovascular disease, new data show.
The interim results of part 1 of the CAPTAIN-T2D study presented at ENDO 2026 are consistent with those of part 1 of the CATALYST trial, researchers found.
“What’s most important is that we are seeing consistency in the incidence of dysfunctional cortisol rhythms and dysfunctional [hypothalamic-pituitary-adrenal] axis in individuals with diabetes and hypertension that is

One of the hardest parts of working with adolescents is that they rarely tell their school counselors exactly what is wrong.
A student does not usually walk into a counselor’s office and say, “I am developing depression,” or “My anxiety is beginning to interfere with my learning.”
More often, the signs are quieter. A student stops turning in work. Another becomes irritable with teachers. One begins asking to leave class often. Another starts sitting alone at lunch or complains of headaches, stomach pain or exhaustion.
From the outside, these changes can look like attitude, laziness, poor

Black kidney donors with a high-risk APOL1 genotype may have reduced kidney function after donation, according to study data published in JAMA Internal Medicine.
Genotyping for APOL1 risk status is controversial due to equity concerns among Black kidney donor candidates and is not often used for evaluations in many transplant centers, according to Chi-yuan Hsu, MD, MSc, nephrology division chief at University of California-San Francisco Health, and colleagues. Understanding whether APOL1 risk status is associated with worsened kidney function after living kidney donation could inform the