Threats to groups like USPSTF could send public health back to the early 1980s

The future of the U.S. Preventive Services Task Force ‘remains unclear,’ and the threat to its structure and scientific processes “have implications for millions of Americans,” according to former members of the task force.
The USPSTF regularly issues recommendations on preventive health services. Under the Affordable Care Act, health insurance companies are required to cover services with an A or B grade recommendation from the task force.
The frequency of new USPSTF recommendations has notably declined in the past year. The task force has not published any draft or finalized recommendations

Anti-IL-18 protein shows ‘very promising’ results for atopic dermatitis

EVO301, a long-acting, injectable interleukin-18 binding protein, rapidly improved moderate to severe atopic dermatitis in adults, according to topline phase 2a results.
The randomized, double-blind, placebo-controlled trial evaluated the safety and efficacy of two 5 mg IV doses of EVO301 for the treatment of moderate to severe atopic dermatitis over 12 weeks, Evommune announced in a press release. Seventy participants were included in the trial, 48 of whom received EVO301 and 22 of whom received placebo.
“The results with this anti-IL-18 are very promising,” Mark Lebwohl, MD, dean for clinical

Q&A: Lessons from a cardiovascular-kidney-metabolic service

A specialized cardio-nephrology service is feasible and could provide interdisciplinary care for patients with cardiovascular-kidney-metabolic syndrome, according to study data published in Kidney360.
Many adults face risks for cardiovascular-kidney-metabolic (CKM) syndrome, with the disorder affecting up to 90% of U.S. adults, according to Karen S. de Wolski, MD, assistant professor of medicine in the division of nephrology at University of Washington Medical Center (UW) in Seattle, and colleagues. With a high proportion of adults potentially at risk, an interdisciplinary approach to care

Pavlik harness weaning protocol may improve acetabular index

Results showed infants with developmental dysplasia of the hip who underwent a Pavlik weaning protocol had improved acetabular index at 6-month follow-up vs. those who experienced immediate ceased treatment after ultrasound normalization.
“Weaning seems to provide some additional benefits beyond stopping once a hip has normalized,” Wudbhav N. Sankar, MD, associate chief in the division of orthopedic surgery and professor of orthopedic surgery at the Children’s Hospital of Philadelphia, told Healio. “The endpoint was X-rays at 6 months of age, and we showed the

Overdiagnosis of papillary thyroid cancer common in US

Most papillary thyroid cancer cases identified in the U.S. between 1991 and 2019 may have been overdiagnosed, according to findings from a microsimulation model published in JAMA Network Open.
Using the Papillary Thyroid Carcinoma Microsimulation Model, researchers found that between 72% and 94% of papillary thyroid cancer cases were overdiagnosed from 1991 to 2019, with overdiagnosis rates estimated to be between 75% and 95% for women and 63% to 90% for men.
Louise Davies, MD, MS, professor of otolaryngology at University of Wisconsin School of Medicine and Public Health, said the findings

VIDEO: Innovation in retina space improves vision, anatomic outcomes

WAIKOLOA, Hawaii — In this expert perspective from Retina 2026, Sunir J. Garg, MD, FACS, FASRS, discusses how real-world data have advanced treatment of retinal vascular diseases by increasing the number of available therapy options.
Garg, of Wills Eye Hospital, said patients with age-related macular degeneration or diabetes lose vision due to disease progression or undertreatment. However, the availability of newer therapies has improved anatomic outcomes and helped patients maintain vision.
“Some of our newer treatments would last longer, and that’s very helpful for patients,”

Clinicians should be concerned about Endangerment Finding repeal

The EPA’s 2009-issued Endangerment Finding, which outlined the dangers of greenhouse gases and how they warm the Earth using science-based evidence, has been repealed by the agency, according to NBC News.
Shortly after this announcement, organizations including the American Thoracic Society and the American Academy of Allergy, Asthma & Immunology released statements denouncing the EPA’s decision.
Additionally, the American Lung Association, the Alliance of Nurses for Healthy Environments, the American Public Health Association and Physicians for Social Responsibility publicized that they

Prenatal lead exposure linked to poorer cognitive function

Increased second trimester lead exposure in women was significantly linked to decreased cognitive function later in adulthood, according to data published in Neurology.
“Our findings should be interpreted with caution in the clinical setting, as many questions about how exactly early lead impacts later cognitive function are still unknown,” Ruby C. Hickman, PhD, MPH, who did this work as a doctoral student at the Harvard T.H. Chan School of Public Health, told Healio. “However, our results suggest that a known history of lead exposure in pregnancy or early life could be a contributor to

FDA approves dupilumab for allergic fungal rhinosinusitis

The FDA granted approval to dupilumab for treating patients aged 6 years and up with allergic fungal rhinosinusitis and a history of sino-nasal surgery, marking the first treatment approved for this indication, according to a press release.
The release noted that the FDA’s decision on dupilumab (Dupixent; Sanofi, Regeneron) was, in part, based on findings from the LIBERTY-AFRS-AIMS trial.
In this randomized, double-blind, placebo-controlled phase 3 trial, 33 adults and children with allergic fungal rhinosinusitis received either 300 mg dupilumab every 2 weeks (weight ≥ 60 kg), 200 mg dupilumab

ASTRO increases access to radiopharmaceutical therapy training

It took Virginia Cancer Specialists nearly 1 year to get the supervised case experience needed to fulfill regulation requirements and start its radiopharmaceutical therapy program in 2014.
Access to training cases has remained a barrier for radiation oncologists to begin using radiopharmaceutical therapy in their own practices.
“There are practices that are technically ready, but they can’t move forward because of the human training component,” Youssef Charara, PhD, DABR, chief medical physicist for radiation support services at Virginia Cancer Specialists, told Healio.
American Society for