Personalized programs designed to reduce falls in older people may make no difference to how often people fall, according to the most comprehensive research review to date.

Getting sick can look very different for people with Down syndrome (DS); illnesses that are mild for most people may lead to serious complications, including pneumonia, hospitalization or the need for intensive care.

Using prostate MRI before a biopsy is a real advance in prostate cancer diagnosis. Multiple randomized trials have shown that imaging the prostate first and then targeting suspicious lesions finds more of the aggressive cancers that matter. As a result, guidelines have progressively strengthened their recommendations for MRI.

Researchers have successfully conducted the first clinical trial using activated regulatory T cells (ATregs, Actileucel)—derived from white blood cells of healthy blood donors. This novel cell therapy aims to prevent graft-versus-host disease (GvHD) following an allogeneic stem cell transplant. The Phase I/II study has yielded extremely encouraging results: ATregs can be produced within 24 hours and injected immediately afterward; administration is safe and well-tolerated by patients—a significant step toward a widely available cell therapy. The research is published in Transplantation and Cellular Therapy.

In a study published in the journal JAMA Network Open, an irregular pattern and consistently higher levels of the stress hormone cortisol in saliva were associated with cognitive decline later in life. Black participants specifically had lower overall cortisol levels and less change in their levels during the day than white participants, according to newly published research.

Could the way we think in our 20s offer clues about our risk of dementia decades later? Large population studies suggest that people who perform better on thinking ability tests in adolescence or young adulthood are less likely to develop dementia later in life. However, cognitive performance in early adulthood is shaped by more than thinking ability alone; it can also reflect education, life experiences and family environment. This makes it difficult to determine whether scores on cognitive tests are a reliable indicator of future dementia risk.

Adults 65 and older with cognitive disorders such as dementia are more likely to suffer negative effects from drugs that treat central nervous system conditions, including anxiety, sleep problems and psychosis. This means more emergency department visits, more frequent and longer hospitalizations, poorer mental health and a greater risk of premature death.

Health workers in parts of the Democratic Republic of Congo badly hit by a deadly Ebola outbreak launched a test vaccination program Saturday to see whether vaccines designed for a different strain of the virus could prove effective in this case.

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows, with the use of continuous glucose monitoring (CGM) devices, sexual intercourse is safe for people living with type 1 diabetes.

New research to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28th – Oct 2nd) shows, with the use of continuous glucose monitoring (CGM) devices people with type 1 diabetes can complete a marathon safely and achieve finishing times similar to runners without diabetes.