Anaphylaxis caused by contrast rare but serious

Anaphylaxis triggered by iodinated contrast media was rare, but severe and refractory cases indicated the need for preparedness, recognition and response, according to a study published in Annals of Allergy, Asthma & Immunology.
Also, the proportion of patients who experienced reactions was substantial even among those who were medicated before receiving their CT scan, according to Eduardo Saadi Neto, MD, of the department of emergency medicine at Mayo Clinic.
“Iodinated contrast is used millions of times each year and is generally safe, but rare anaphylactic reactions can be severe or

Tool uses eGFR trends to predict kidney graft failure at 3 years

A risk prediction model using longitudinal eGFR data could help identify kidney transplant recipients at risk for graft failure, according to study data published in the Clinical Journal of the American Society of Nephrology.
Scarcity of kidneys for transplant remains a consistent challenge in treating patients with end-stage kidney disease, and 10% of patients on the waitlist are repeat transplant candidates, according to Heather Thiessen Philbrook, MMath, instructor in medicine in the division of nephrology at Johns Hopkins School of Medicine, Chirag R. Parikh, MBBS, PhD, director of the

EPA excluding lives saved from air pollution cost calculations

When making rules on fine particulate matter and ozone limits, the EPA will no longer calculate the monetary value of lives saved due to lowering these air pollutants, according to The New York Times.
In documents reviewed by The New York Times, the decision to eliminate health effects from cost-benefit analyses required for clean-air regulation was made by the Trump administration, which also noted that the benefits estimated with the change to the National Ambient Air Quality Standard for fine particulate pollution from 12 µg/m3 to 9 µg/m3 under the Biden administration were doubtful.
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Incidental splenomegaly may be risk factor for blood cancer

Individuals with incidentally detected splenomegaly may be at increased risk for blood and liver cancers, as well as cirrhosis.
An evaluation of more than 47,000 individuals who had a CT or MRI found those in the 99th percentile of spleen length had a five times greater risk for hematologic malignancies than those in the 26th to 74th percentiles. Those with spleen volumes in the 99th percentile had 11 times the risk.
“Individuals with incidentally detected spleen length of 140 mm or greater or spleen volume of 500 mL or greater had markedly increased risk of hematologic cancer likely warranting

Air pollution may increase risk for gout

Individuals with metabolic signatures for air pollutants such as particulate matter, nitrogen dioxide and nitrogen demonstrate an increased risk for gout, according to results of a cohort study published in Arthritis Care & Research.
“Apart from some well-known modifiable lifestyle behaviors, such as purine-rich food intake, alcohol drinking, and obesity, air pollution has also been regarded as a vital risk factor in gout development,” Peng Hu, PhD, from the school of public health at Sun Yat-sen University in Guangzhou, China, and colleagues wrote. “Recently, the links

Alcohol-intoxicated, severely injured patients often misdiagnosed, receive less treatment before hospital arrival

Physical trauma is the leading cause of death in young adults. About 1 in 4 patients with multiple trauma is alcohol-intoxicated at the time of injury, typically suffering from a fall or a traffic accident. The medical assessment of severely injured people on the scene and en route to the hospital is a crucial and challenging step, determining life-saving measures, time-critical interventions, transport decisions, and hospital destinations.

In WA, thousands are forgoing health insurance this year: Here’s why

Ambrose Bittner, 63, didn't want to go uninsured. But the self-employed travel planner has been without health coverage since the beginning of the year. Bittner, who lives in Issaquah, is one of thousands of Washington state residents who decided to disenroll from health insurance, following the expiration of subsidies that helped millions of people afford high premiums.