Physical function is a crucial predictor of survival after heart failure, mortality risk model indicates

Monitoring and treating heart failure (HF) is a challenging condition at any age. Several models, such as Atrial fibrillation, Hemoglobin, Elderly, Abnormal renal parameters, Diabetes mellitus (AHEAD), and BIOlogy Study to TAilored Treatment in Chronic Heart Failure (BIOSTAT) compact, have been developed to predict the likelihood of a patient's survival based on clinical factors such as arrhythmia, anemia, age, diabetes, and ejection fraction.

A silent signaling network deep in the gut protects against inflammatory intestinal disorders, scientists find

Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem cells lining the gut wall are not just rebuilding tissue—they are listening and signaling. When certain strains of Escherichia coli brush past, these cells can sense a telltale molecular signature: flagellin, the protein that powers a bacterium's whip-like tail. That signal sets off a chain reaction, summoning immune cells that repair damage and help restore the gut's protective barrier.

Do you need to worry about thyroid nodules?

Your thyroid is a small, butterfly-shaped gland in the front of your neck. Its main job is to produce thyroid hormones, which help regulate your body's metabolism and control your heart rate, body temperature, growth and development. A thyroid nodule is a small bump or growth that develops on this gland. Thyroid nodules can cause a range of symptoms—or none at all.

Scientists develop first-of-its-kind antibody to block Epstein Barr virus

Fred Hutch Cancer Center scientists reached a crucial milestone in blocking Epstein Barr virus (EBV), a pathogen estimated to infect 95% of the global population that is linked to multiple types of cancer, neurodegenerative diseases and other chronic health conditions. Using mice with human antibody genes, the research team developed new genetically human monoclonal antibodies that prevent two key antigens on the surface of the virus from binding to and entering human immune cells.

Oxytocin reverses anxiety-like behavior after three months of isolation in mice

Periods of prolonged social isolation have long been associated with difficult emotions and, in some cases, with the emergence of psychiatric symptoms, such as depression, anxiety, and difficulties connecting with others. Some past psychology studies have suggested that chronic isolation during adolescence, the critical stage between childhood and adulthood, can disrupt the structure and functioning of a brain region known as the prefrontal cortex (PFC).