Inpatient rehab lags for patients with acute neurological injury

Patients with stroke and traumatic brain injury often were not admitted to inpatient rehabilitation facilities despite the benefits of the care they administer, according to a study published in Neurology.
Disparities in these admissions also indicate a need for post-acute rehabilitation planning that is more equitable and evidence-based, Farhaan S. Vahidy, PhD, MBBS, MPH, FAHA, associate vice president for research and chief scientific officer at TIRR Memorial Hermann in Houton, Texas, and colleagues wrote.
“This study was prompted by a question we face often in clinical care and health

CMS adopts performance-based standards for CRC biomarker tests

CMS established a new national framework setting performance thresholds to qualify noninvasive, biomarker-based colorectal cancer screening options — including FDA-approved stool- and blood-based tests — for coverage.
“The CMS coverage decision provides benchmarks for novel noninvasive tests to meet and exceed to gain coverage, and learn from the experience of currently approved tests,” Aasma Shaukat, MD, MPH, Robert M. and Mary H. Glickman Professor of Medicine at NYU Grossman School of Medicine, told Healio. “It also allows newer test makers to understand the current performance standards

Knotless pull-through technique for hip labral reconstruction

Labral tears are among the most common pathologies treated in hip arthroscopy.
When the labrum is irreparable — whether due to segmental defects, calcification or failed previous repair — labral reconstruction may be the next best step. Reconstructing the labrum restores the suction seal, joint stability and normal kinematics.
Source: Benjamin G. Domb, MD
While various reconstruction techniques exist, the knotless pull-through method has proven particularly efficient and reproducible. One of its biggest advantages is that it eliminates the need for measuring the labral defect, which can be time

Topline data: Zasocitinib outperforms deucravacitinib for plaque psoriasis

Zasocitinib outperformed deucravacitinib for the treatment of patients with moderate to severe plaque psoriasis, according to topline data.
As Healio previously reported, zasocitinib (Takeda) is an investigational, highly selective oral tyrosine kinase 2 (TYK2) inhibitor that blocks interleukin-23 and other pathways driving psoriasis. In the phase 3, head-to-head trial, researchers found that more than 35% of patients who received zasocitinib achieved the primary endpoint of PASI 100 by week 16 — over 2.5 times the response rate observed for deucravacitinib (Sotyktu, Bristol Myers Squibb),

Ozempic tied to improved quality of life in type 2 diabetes, CKD

Compared with placebo, semaglutide was associated with improved quality of life outcomes for patients with type 2 diabetes and chronic kidney disease.
Study data were presented at the European Renal Association Congress in Glasgow, Scotland.
In the FLOW trial, semaglutide (Ozempic, Novo Nordisk) demonstrated efficacy in reducing risks for major adverse kidney events and all-cause mortality compared with placebo for patients with type 2 diabetes and CKD, according to Johannes F. E. Mann, MD, professor of medicine at the Friedrich Alexander University in Germany, and colleagues. Building off

Interventional approach needed in pseudophakic glaucoma patients

MIAMI — Combining minimally invasive glaucoma surgery with pharmaceutical drug delivery is an option to lower IOP in patients who are pseudophakic, according to a speaker.
At Sunshine Eye & Retina, Zarmeena Vendal, MD, urged ophthalmologists to avoid eye drops and incisional surgery when possible in patients who previously underwent cataract surgery. Instead, they should prioritize an interventional approach to treatment.
“My pseudophakic procedure of choice is often goniotomy, and that is with or without iDose (Glaukos),” Vendal said during a presentation.
{{VIDEO}}
Vendal discussed a case

Increased body size elevates risk for bladder cancer in men

Body size, including both body mass index and waist circumference, has a significant association with bladder cancer in men, but not women.
An analysis of more than 20,000 individuals with incident disease found men with obesity had a 16% higher risk for bladder cancer than those with normal weight. Incremental increasing BMI, waist circumference and height were all associated with elevated risk.
“Maintaining a healthy body weight, together with smoking cessation and reduced exposure to occupational carcinogens, is likely to contribute to reducing bladder cancer incidence worldwide,” Nina

Maternal cardiac disease tied to offspring congenital heart disease

A significant association was found between maternal heart disease during pregnancy and risk for congenital heart disease in offspring within 1 year of birth, researchers in China reported.
In study findings published in JAMA Network Open, the researchers noted that targeted surveillance and intervention of modifiable risk factors among pregnant individuals may help lower risk for congenital heart disease among offspring.
“Our findings highlight the need for early echocardiographic screening in offspring of mothers with cardiac disease, particularly right ventricular outflow tract

Novel GLP-1/amylin drug lowers HbA1c, weight in type 2 diabetes

NEW ORLEANS — A novel unimolecular GLP-1/amylin receptor agonist conferred reductions in HbA1c and body weight for adults with type 2 diabetes, according to data from a phase 2 trial.
Zenagamtide (Novo Nordisk) is under investigation for once-weekly subcutaneous and once-daily oral administration for the treatment of type 2 diabetes and obesity. As Healio previously reported from topline results released in 2025, the medication, formerly known as amycretin, conferred greater weight loss for adults with obesity than placebo in a phase 1b/2a trial. New data from another phase 2 trial presented

Critical illness in high-risk pregnancy rises after abortion ban

ORLANDO — Among hospitalized pregnant women in Texas with high-risk features, rates of critical illness rose after implementation of an abortion ban, according to results presented at the American Thoracic Society International Conference.
These data on Texas Senate Bill 8 (SB8), the bill that “banned abortion after embryonic cardiac activity” in September 2021, were also simultaneously published in American Journal of Respiratory and Critical Care Medicine.
“Our study shows that while there does not appear to be an association between SB8 and critical illness among the general population of