Active, passive smoke exposure tied to higher rates of hidradenitis suppurativa in youths

Children and adolescents with hidradenitis suppurativa had higher rates of both active and passive smoke exposure compared with children who did not have the disease, according to a study published in Pediatric Dermatology.
Findings showed children exposed to both active and passive smoke were 4.8 times more likely to have HS compared with those who were not, with secondhand smoke exposure alone associated with 1.64 times higher odds of an HS diagnosis among children and teens.
“HS can be particularly difficult for children and adolescents. It can cause pain and scarring and can have a major

New framework for managing women’s heart health

Societies issued a three-part publication series aimed at improving heart health outcomes for women through a life course approach, tying CVD risk to specific female life stages, which could enable earlier intervention.
The series also aimed to address the underrepresentation of women in science and the fragmented nature of current women’s CV care. Sadiya S. Khan, MD, MSc, FAHA, Magerstadt Professor of Cardiovascular Epidemiology and associate professor of cardiology and preventive medicine at Northwestern University Feinberg School of Medicine, said the work focuses on moving away from

Aspirin does not reduce risks for major CV events vs. usual care in CKD

DENVER — Low-dose aspirin did not significantly reduce risks for major CV events vs. usual care among patients with chronic kidney disease, according to data presented at ASN Kidney Week.
“We’re not in a place where we should be offering aspirin for primary prevention at this stage,” Hugh Gallagher, MBBS, MS, MSc, PhD, consultant nephrologist at Epsom and St Helier University Hospitals NHS Trust, told Healio.
The primary interventions for preventing CV events in CKD are limited to lipid-lowering therapies and SGLT2 inhibitors, according to Gallagher. Aspirin may provide CV benefits or risks

Obesity impact on women can be related to hormonal changes

BOSTON — Obesity has a different impact on women than it does on men, and women can benefit from weight loss at any stage of life, a speaker said at the Cardiometabolic Health Congress Women’s Cardiometabolic Health and Wellness Masterclass.
“Obesity is a disease. It affects women during the periods of hormonal change more because of the way those hormone changes interact with the hormones that go to the brain and regulate energy balance,” Healio | Endocrine Today Editorial Board Member Caroline M. Apovian, MD, FACN, FACP, FTOS, DABOM, professor of medicine at Harvard Medical School and

CagriSema lowers weight for women across reproductive lifespan

Once-weekly CagriSema reduced weight by 25% at 68 weeks for women with overweight or obesity, and weight loss was observed among women across all reproductive stages, according to data from two posters.
As Healio previously reported, adults receiving a once-weekly combination of cagrilintide 2.4 mg and semaglutide 2.4 mg (Novo Nordisk) in the REDEFINE 1 trial lost 20.4% of their body weight at 68 weeks compared with a 3% weight loss for those receiving placebo, according to the treatment policy estimand. In post hoc analyses presented at the Annual Meeting of The Menopause Society, researchers

Recent developments may change care landscape in hepatitis B

NASHVILLE — In this Healio video, Arun B. Jesudian, MD, discusses hepatitis B developments including new therapies for highly selective patients, updated treatment guidelines and different vaccination recommendations from the ACG Annual Meeting.
“The hepatitis B space is changing and, particularly, this might be an inflection point in how we take care of certain patients with hepatitis B,” Jesudian, professor of clinical medicine, director of liver quality and inpatient liver services at Weill Cornell Medicine, told Healio.

Novel iDIET boosts histologic, endoscopic response in eosinophilic esophagitis

NASHVILLE, Tenn. — An allergen-specific, immune signature-directed diet led to significant improvements in patients with eosinophilic esophagitis compared with a sham elimination diet, according to results of a small, randomized study.
Dietary elimination is often recommended for patients with eosinophilic esophagitis, because it can directly address the cause of the condition. However, traditional allergy tests are not advised to guide removal of food triggers, according to researchers.
“Food trigger identification remains a major challenge,” Evan S. Dellon, MD, MPH, FACG,

Speaker shares lay press writing tips

During a Healio Community webinar, Adaira Landry, MD, MEd, presented the mechanics of writing perspective or opinion pieces for the lay press, detailing how healthcare professionals can venture beyond the field of formal academic writing.
Landry acknowledged that publishing as a healthcare professional can initially be challenging — especially for women and women of color — due to market competition and limited professional training and mentorship opportunities. Still, she emphasized the benefit of amplifying new voices and perspectives.
“The point of this lecture is to inspire you all to know

Retatrutide reduces osteoarthritis pain in patients with obesity

Treatment with retatrutide significantly reduced knee osteoarthritis pain and body weight among adults with obesity without diabetes, according to results published in The New England Journal of Medicine.
“Retatrutide is a triple-receptor agonist targeting the G-protein-coupled receptors for glucose dependent insulinotropic polypeptide, glucagon-like peptide-1, and glucagon,” Ania M. Jastreboff, MD, PhD, of the Yale University School of Medicine, and colleagues wrote. “In a phase 2 trial involving participants with obesity, once-weekly subcutaneous retatrutide (at a dose of