NEW ORLEANS — Higher activity levels in the immediate postoperative recovery period after total knee arthroplasty may reduce the risk for developing venous thromboembolism, according to results presented here.
“As technology keeps developing, we want to use technology to our advantage and for the benefit of our patients. This is very promising as we are able to collect more and more data, and we are able to prevent more and more complications,” Michele R. D’Apuzzo, MD, of the University of Miami, told Healio about results presented at the American Academy of Orthopaedic

James Song, MD, FAAD, Co-CMO, discussed “exciting data” on GLP-1 receptor agonists and psoriasis presented at Maui Derm 2026.
Song, director of clinical research at Frontier Dermatology in Mill Creek, Washington, spoke about the potential benefits of GLP-1 receptor agonists for psoriasis and other conditions.
“There might be some additional benefits for these GLP-1 receptor agonists that go beyond just skin clearance,” Song told Healio.

In this video interview, James Song, MD, FAAD, Co-CMO spoke about his presentation from Maui Derm 2026 on what’s new with current therapies for psoriasis.
Song discussed long-term efficacy and safety data for bimekizumab (Bimzelx, UCB).
“What we’re seeing is just very consistent, deep and durable responses through the 5-year mark,” Song, director of clinical research at Frontier Dermatology in Mill Creek, Washington, told Healio.
He also discussed brodalumab (Siliq, Ortho Dermatologics) as a treatment option for refractory patients as well as its 7-year safety data.

Children whose mothers had diabetes during pregnancy had a higher risk for developing epilepsy during childhood, according to a study published in Pediatrics.
“Our findings highlight that prenatal factors can play an important role in the development of epilepsy in children,” Bénédicte Driollet, PhD, a biostatistician and epidemiologist at McGill University in Montreal, told Healio. Driollet worked on this study while completing her postdoctoral fellowship in epidemiology at McGill University.
The retrospective birth cohort study examined the outcomes of 2,105,553 children born in Ontario,

Spring’s daylight saving time shift can lead to sleep deprivation and the disruption of circadian rhythms, negatively impacting health in a plethora of ways, research shows.
“If individuals have health conditions, especially if they have cardiometabolic issues, they should really try to take it easy that day and, if possible, shift 20 minutes per day a few days ahead of time,” chronobiologist Emily Manoogian, PhD, told Healio.
Manoogian is a senior staff scientist at the Salk Institute for Biological Studies and an executive member of the Center for Circadian Biology and Medicine at UC San

In-hospital mortality was significantly higher for younger women vs. younger men after a first heart attack, with women receiving fewer cardiac procedures and having more nontraditional cardiovascular risk factors, researchers reported.
A study evaluating trends in first MI outcomes, both STEMI and non-STEMI, based on sex was published in the Journal of the American Heart Association.
“Prior to this, we had done an analysis within the same dataset looking at risk factors in young folks, and the troubling finding that we found is that both traditional risk factors, high blood pressure and

Kyowa Kirin announced it is discontinuing all ongoing clinical trials for rocatinlimab, an investigational anti-OX40 monoclonal antibody, after a safety review identified “emerging concerns” of malignancies.
Rocatinlimab, which targets memory T cells, was being assessed in multiple phase 2 and 3 trials for moderate to severe atopic dermatitis, moderate to severe uncontrolled asthma and prurigo nodularis.
In a press release, the company said its most recent safety review conducted over the last several weeks identified “emerging concerns of malignancies with possible viral or immune-related

A selective cytopheretic device for pediatrics demonstrated safety and potential benefit in 21 pediatric patients with life-threatening sepsis-associated AKI requiring kidney replacement therapy, according to a company press release.
Currently, the device (Quelimmune, SeaStar Medical) is the only FDA-approved therapy for pediatric patients in the ICU with AKI due to sepsis or a sepsis-like condition in need of kidney replacement therapy, according to Stuart Goldstein, MD, director of the Center for Acute Care Nephrology at Cincinnati Children’s and a SeaStar Medical scientific advisory board

NEW ORLEANS — Results presented here showed negative pressure wound therapy is a safe adjunct for soft tissue sarcoma treated with neoadjuvant radiation therapy. However, it did not reduce the rate of soft tissue infection.
“Wound vacs do not decrease the rate of wound complications, but they are safe and offer similar patient-reported outcome measures and pain scores relative to standard dry gauze dressings,” Jason Silvestre, MD, chief resident at the Medical University of South Carolina, told Healio about results presented at the American Academy of Orthopaedic Surgeons

Diet has a tremendous influence over health, so encouraging patients to adopt a whole food, plant-based diet will help them live longer, more vibrant lives, according to one of the most prominent names in nutrition.
Michael Greger, MD, a founding member and fellow of the American College of Lifestyle Medicine (ACLM) and founder of NutritionFacts.org, has released a new documentary, “How Not to Die,” based off his book of the same name.
The film explores a basic premise that diet is the greatest threat to most people’s health, according to a press release. It “exposes the role of the standard