Measles, which was declared to be eliminated in 2000 in the United States, has seen a resurgence, with more than 2,000 cases documented in 2025.
This is the highest number of cases since elimination was achieved over 2 decades ago, according to the Infectious Diseases Society of America.
In this Beneath the Surface video interview, Joel M. Gelfand, MD, MSCE, FAAD, the James J. Leyden Professor of Clinical Investigation and professor of dermatology and epidemiology at University of Pennsylvania’s Perelman School of Medicine and Healio Dermatology’s Chief Medical Editor, spoke with Amy S. Paller,

WAIKOLOA, Hawaii — At Orthopedics Today Hawaii, John E. (Jed) Kuhn, MD, spoke about what to do for failed rotator cuff repairs.
“It’s probably about a third of the ones that you fix actually do fail. But most of those patients don’t have symptoms — they don’t have pain, they don’t have weakness, they do very well,” Kuhn, Kenneth D. Schermerhorn professor and chief of the division of sports medicine at Vanderbilt University Medical Center, said.
He said it is important to figure out what the patient’s complaint is, which he divides into pain

Biomarkers associated with cognitive impairment differ between men and women with chronic kidney disease, according to data published in American Journal of Physiology – Heart and Circulatory Physiology.
Previous research explored the association between CKD and cognitive impairment, with the prevalence of cognitive impairment estimated to be 30% to 60% higher for patients with end-stage kidney disease compared with those without, according to Komal Sodhi, MD, associate professor of surgery at Marshall University Joan C. Edwards School of Medicine, and colleagues. However, mechanisms behind

Clear corneal incisions have become the default entry point for routine phacoemulsification due to their simplicity, rapid healing and low induced astigmatism in healthy eyes.
However, they rely heavily on the structural and optical integrity of the cornea.
When the cornea is thinned, scarred, unstable or otherwise fragile, creating a standard corneal incision can compromise safety and hinder postoperative recovery. For this reason, the scleral tunnel incision remains a useful technique, offering structural advantages in eyes in which a corneal approach could worsen existing pathology.
Eyes with

Historically, patient-reported outcome measures were primarily utilized for research purposes in orthopedics.
However, renewed interest in patient-reported outcome measures (PROMs) paired with the mandatory PROMs reporting in the patient-reported outcome-based performance measure policy from CMS has shed new light on the potential use of these data to aid in clinical decision-making and individualize patient care at the point of service.
“Obviously, PROMs are just one of many variables that inform the complex decision of when it is appropriate to proceed with joint replacement, but they are

The FDA has granted fast track designation to a vectorized antibody that targets RNA-binding proteins characteristic of neurodegenerative diseases.
According to a press release from VectorY Therapeutics, the therapy is specifically designed to address ALS.
VTx-002, its first-in-class vectorized antibody targeting TDP-43 pathology, will be investigated in a phase 1/2 clinical trial, dubbed PIONEER-ALS, examining safety, tolerability and pharmacodynamics of the novel therapeutic, the company said in the release.
VectorY expects to open enrollment in the PIONEER-ALS study in the near future.
This

Only about one in five people with cancer enroll in clinical trials, and the largest barrier to participation may be far different than many people believe.
Financial factors — not lack of awareness or understanding, mistrust of the health care system, race or other sociodemographic variables — are the biggest hurdle, according to results of a retrospective cohort study.
Strategies to address patients’ real-world costs — such as transportation, childcare or lost wages — are necessary to ensure more equitable trial participation, researchers concluded.
“Many studies have shown travel distance,

The past year was a busy one for the American Association of Clinical Endocrinology and its 2025 president, Scott Isaacs, MD, FACP, FACE.
Isaacs, who is also an adjunct associate professor of medicine at Emory University and a member of the Healio | Endocrine Today Editorial Board, described 2025 as a “record year” for AACE regarding the number of consensus statements the organization published. In February, the organization released a clinical practice guideline on the pharmacological management of dyslipidemia. This was followed by the publication of a consensus statement detailing an

Less than 30% of pediatric patients who survived ICU hospitalization followed up with their primary care provider within 1 week of discharge, according to findings published in CHEST.
“These results highlight the need to determine how we can partner with clinicians throughout the spectrum of health care, from the inpatient provider in the ICU to the child’s pediatrician, to try to ensure the best outcomes for children and their families,” Erin F. Carlton, MD, clinical associate professor in pediatric critical care at University of Michigan Health, told Healio.
In this study, Carlton and

When asked about food allergy management, more individuals reported choosing allergen avoidance over oral immunotherapy or omalizumab, according to data published in The Journal of Allergy and Clinical Immunology: In Practice.
“As the landscape of food allergy management changes, clinicians want to better understand which therapies are best suited for specific patients,” S. Shahzad Mustafa, MD, division head of allergy, immunology and rheumatology at Rochester Regional Health and clinical associate professor of medicine at the University of Rochester School of Medicine and Dentistry, told