An international team of experts recently came together to update sepsis care guidelines for adults for the first time since 2021. The updates have profound implications for the management of sepsis, which is responsible for approximately 11 million deaths per year worldwide. Co-led by U-M's Hallie Prescott, M.D. and Massimo Antonelli, M.D. of Catholic University in Rome, Italy, the 69-person panel reviewed research, concentrating on areas of care that may have new evidence supporting a change in practice.