Oral drug may allow early treatment of diabetic retinopathy

Editor’s note: This is a developing news story. Please check back soon for updates.
Some patients with nonproliferative diabetic retinopathy had reduced vascular leakage or macular exudation after being treated orally with danegaptide, according to a study presented at Angiogenesis, Exudation, and Degeneration 2026.
Danegaptide (Breye Therapeutics) was well tolerated in the phase 1b study, paving the way for a phase 2 trial, according to a press release from Breye.
The results were presented by Carl D. Regillo, MD, director of the retina service at Wills Eye Hospital and a member of Breye’s

AI model accurately detects placenta accreta during pregnancy

A novel AI model accurately identified placenta accreta spectrum, or PAS, in pregnancy before delivery, according to an analysis presented at The Pregnancy Meeting.
“The findings in this feasibility study are very promising,” Alexandra L. Hammerquist, MD, a maternal-fetal medicine fellow at Baylor College of Medicine, told Healio. “What is especially encouraging about our results is that our AI model was able to capture all cases of PAS, without any false negatives.”
PAS is a complication “in which the placenta abnormally attaches to the uterine wall, often associated with prior uterine

Q&A: These little-known viruses could cause human epidemics

Canine coronavirus and influenza D are two zoonotic viruses that researchers say have “considerable potential” for causing future epidemics in people.
In an article published recently in Emerging Infectious Diseases, John A. Lednicky, PhD, and colleagues summarized studies on influenza D and canine coronavirus that covered the viruses’ respective “discoveries” to their possible recorded transmissions from animals to people.
Data “strongly indicate that these viruses are major newly recognized threats,” they wrote, also warning that “diagnostics and surveillance for the viruses are lacking.”

Laws restricting abortions linked to high maternal death rates

Rising state-level abortion restrictions in the United States were linked to a similar, parallel rise in maternal deaths from 2005 to 2023, according to research presented at The Pregnancy Meeting.
Marie C. Anderson, MD, a resident in the department of OB/GYN at Columbia University Vagelos College of Physicians and Surgeons in New York City, told Healio her interest in abortion legislation has been informed by her experience as a child in “a pretty conservative state where abortion has been considered taboo at best, and a mortal sin at worst,” and then as a student on the East Coast, where

Outdated mortality benchmarks risk missing early signs of famine and delay recognizing mass starvation

Recent global crises have exposed the limits of a universal mortality threshold for declaring famine—an approach that can obscure how famine actually unfolds across different populations. In a paper published in The Lancet, researchers at Columbia University Mailman School of Public Health and colleagues call for a fundamental re-examination of how famine thresholds are defined.

Adolescent with chronic right hip pain, limb length discrepancy

At the time of presentation, the patient was a 17-year-old male referred for evaluation of chronic right hip pain and limb length discrepancy, which was managed with a shoe lift.
His surgical history was notable for a right basicervical femoral neck fracture from a motor vehicle crash at age 15 (Figures 1 and 2) treated with an open reduction and dynamic hip screw (Figure 3). This progressed to a nonunion (Figure 3), and he subsequently underwent a revision valgus-producing proximal femoral osteotomy with blade plate fixation approximately 1 year prior to presentation (Figure 4). He had

Prevent reverse pupillary block to improve patient comfort

WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2026, Jennifer M. Loh, MD, discusses her technique to resolve reverse pupillary block during cataract surgery.
“This is a pretty common occurrence in cataract surgery and can occur many times in patients with long axial length eyes,” she told Healio.
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Loh said she uses a second instrument to lift the iris away from the anterior capsule, or if the block occurs during the irrigation-aspiration portion of surgery, she said the surgeon can use the irrigation device to lift the iris.
“Prevention is important because once

Pediatric data collection in neurodegenerative disease faces obstacles

SAN DIEGO — Compiling a biorepository of pediatric patients with a range of neuroinflammatory conditions may be feasible with a longitudinal study, but obstacles to accurate data acquisition remain, according to data presented at ACTRIMS.
The Brain Immune Gut (BIG) Initiative was created to provide a comprehensive record of data and specimens from individuals of all ages with demyelinating central nervous system disorders or neuroinflammatory disease. However, researchers have limited data from the pediatric population.
“The pediatric population is such a difficult population to study. There’s

Product labels may overstate statins’ adverse effects

Many warnings, such as muscle pain and new-onset diabetes, found on packaging of popular statins were not supported by data from randomized clinical trials, according to new data published in The Lancet.
Statin labeling may overstate undesirable effects of statin therapy, misleading physicians and their patients, and revisions should be considered, according to a new meta-analysis from the Cholesterol Treatment Trialists’ Collaboration.
“Statin product labels list certain adverse health outcomes as potential treatment-related effects based mainly on information from nonrandomized studies which