Study reveals a global lack of knowledge about perimenopausal symptoms

Commonly recognized perimenopause symptoms often differed from symptoms that women actually reported experiencing the most, according to results of a recently published cross-sectional survey.
The survey was completed by 17,494 women from 158 countries.
“I think the findings are fascinating and demonstrate a clear gap between knowledge about perimenopause and the symptoms women are experiencing,” Stephanie S. Faubion, MD, MBA, MSCP, medical director for the Menopause Society, director for the Mayo Clinic Center for Women’s Health, and a study author, told Healio. “It’s also notable that while

How severe maternal morbidity impacts long-term kidney outcomes

One in three pregnant women on maintenance dialysis experienced severe maternal morbidity, according to study data published in the Journal of the American Society of Nephrology.
Additionally, the data showed that these women had higher mortality risks and were less likely to receive a kidney transplant years after delivery.
Previous research has shown risks for severe maternal morbidity affect nearly one in four pregnancies for women with advanced chronic kidney disease, according to Monica L. Reynolds, MD, MSCR, associate professor of medicine in the division of nephrology and hypertension at

Discomfort in sharing feelings linked to poor stroke outcomes

Patients who do not feel comfortable expressing their feelings to their loved ones felt greater loneliness and experienced more disability, according to data presented at the International Stroke Conference.
“Changes in social relationships after a stroke may lead to social isolation and undermine recovery,” E. Alison Holman, FNP, PhD, associate dean for academic personnelUC Irvine Sue & Bill Gross School of Nursing, .
Often, Holman continued, people do not know what to say to support family and friends who have had a stroke and may make these survivors uncomfortable talking about their

Gait analysis may improve lumbar degenerative disease treatment

Results showed clinical gait analysis may provide surgeons with an objective measure to assess preoperative disability associated with lumbar degenerative disease and early postoperative function following lumbar decompression surgery.
“Most surgical outcomes these days are radiographic, which are very accurate, but they are static. Or they are based on patient-reported outcomes, which are subjective,” Ram Haddas, PhD, MBA, assistant professor in the departments of orthopedics at the University of Rochester Medical Center, told Healio about data he presented at the North American

Deupirfenidone’s advance into phase 3 addresses need in IPF

Deupirfenidone, a potential new treatment for idiopathic pulmonary fibrosis, is set to be tested in a phase 3 trial this year after a successful phase 2b trial and meeting with the FDA, according to a company-issued press release.
If this trial yields positive results, deupirfenidone (LYT-100, PureTech Health) would be one step closer to becoming the fourth therapy for IPF to receive FDA approval.
As Healio previously reported, patients with IPF in the phase 2b ELEVATE IPF trial had less FVC decline between baseline and 26 weeks with receipt of three daily doses of 825 mg deupirfenidone vs.

Baseline HAE attack rate does not impact berotralstat efficacy

Among patients with hereditary angioedema, baseline attack frequency and disease type did not change improvements in monthly attack rate seen with berotralstat, according to data published in Allergy, Asthma & Clinical Immunology.
“These real-world results reinforce clinician confidence in long-term use of berotralstat [Orladeyo, BioCryst Pharmaceuticals] for preventing HAE attacks and support its consideration as a viable treatment option regardless of HAE type or prior HAE attack frequency,” Mark Davis-Lorton, MD, allergist/immunologist at ENT and Allergy Associates, told Healio.
Using

Alcohol-specific ED visits doubled in the last 20 years

Alcohol-specific ED visits doubled among individuals in the United States from 2003 to 2022, according to a report from the National Center for Health Statistics.
“A rising prevalence of alcohol-related emergency department visits has been observed in the United States, increasing the burden on hospital resources,” Xianghua Yin, PhD, MD, senior statistical consultant at CDC, and colleagues wrote.
A 2024 report from the Substance Abuse and Mental Health Services Administration showed that alcohol was the most common substance involved in substance-related ED visits from 2021 to 2023, with double

PTSD due to combat deployment may trigger fibromyalgia

Stress associated with combat deployment to a warzone among U.S. military service members is a significant factor in the onset of fibromyalgia, according to data published in Arthritis Care & Research.
“High levels of stress may increase the risk of the onset of new conditions, including fibromyalgia,” Jay B. Higgs, MD, of the Brooke Army Medical Center, Joint Base San Antonio-Fort Sam Houston, and the University of Texas Health Science Center at San Antonio, and colleagues, wrote. “The relationship between combat exposure and fibromyalgia was initially recognized during

Researchers identify key mechanism driving progression of fatty liver disease to cancer

According to recent reports from the Korean government, the incidence of alcoholic liver disease—previously the leading indication for liver transplantation—has been decreasing. This trend initially raised expectations that the medical burden of liver transplantation and liver-related mortality would decline. However, the current reality does not reflect this expectation. In addition, fatty liver disease is also increasing steadily due to modern lifestyle factors, and projections indicate that the demand for liver transplantation will continue to rise, with fatty liver-related cases increasingly replacing those caused by alcoholic liver disease.

‘Hidden’ costs of social care after a hip fracture exceed £1.25 billion a year in the UK

Hip fracture is the most common serious injury in older adults, affecting more than 80,000 people in the U.K. every year. The loss of mobility, function, and independence after a hip fracture means that many people need additional support. This varies between individuals but typically involves a combination of formal paid care, informal care from family and friends, and changes to the home environment.