Hooked on Primary Care with Aerial Petty, DO

During medical school, so many things made me mad. I enjoyed school, so it wasn’t the curriculum; it was the glaring healthcare inequities everywhere I looked.
I chose medicine because I love people. For me, it didn’t go much deeper than that. Science was awesome, but it was the human ability to use science to improve our quality of life and maximize our happiness that I really related to. So, when I realized as a medical student that some patients’ health outcomes were being determined by their zip code, their income or their ethnicity, and that these factors could not only bar their access

Q&A: ACP calls for stronger FDA oversight of dietary supplements

ACP has released a position paper on dietary supplements’ controversial regulations, offering FDA suggestions for a more proactive approach.
In the United States, dietary supplements are considered a subcategory of food, so they are not required to undergo FDA review and approval, according to the position paper. That “inadequate regulatory framework,” according to the paper, “has allowed adulterated and mislabeled products to repeatedly enter the market and poses a health threat to the public.”
As Healio previously reported, some companies have used these regulations as loopholes to offer

HeFH more common among South Asians than prior estimates

SCOTTSDALE, Ariz. — The prevalence of genetic high cholesterol is estimated to be approximately sevenfold higher in the South Asian population compared with previous estimations in the global general population, a speaker reported.
Compared with South Asian individuals without heterozygous familial hypercholesterolemia, those with heterozygous FH (HeFH) may have an up to twofold greater risk for major adverse CV events, premature atherosclerotic CVD, CV death and all-cause death, according to a presentation.
At the American Society for Preventive Cardiology Congress on CVD Prevention,

Harrow acquires global rights to Tyrvaya

Harrow has acquired the global rights to Tyrvaya from Viatris in a deal worth up to $100 million, according to a press release.
Harrow will pay $30 million at closing, which is expected in the second half of the year. The agreement also includes payments of up to $70 million based on net sales, according to the release.
Tyrvaya (varenicline solution) is a nasal spray indicated for the treatment of signs and symptoms of dry eye disease. It is currently approved in the U.S., China and Taiwan.
With its different mechanism of action, Harrow said Tyrvaya will be a good complement for Vevye

BMI plus waist circumference best method to diagnose obesity

The use of BMI or waist circumference to diagnose obesity may be more accurate than The Lancet Diabetes & Endocrinology commission’s definition for the disease, researchers reported in JAMA Network Open.
As Healio previously reported, a report published in The Lancet Diabetes & Endocrinology in 2025 proposed a new definition for obesity that stated healthcare professionals could diagnose the condition if a person has one measure of excess adiposity plus an elevated BMI, two measures of excess body fat without elevated BMI, or by using DXA scan or another direct body fat metric. In a

Benefits of GLP-1s, SGLT2i may vary by kidney failure risk

Kidney failure risk may impact treatment effectiveness of SGLT2 inhibitors vs. GLP-1 drugs for veterans with type 2 diabetes, according to study data published in the Journal of the American Society of Nephrology.
Currently, no randomized controlled trials have compared the effectiveness of SGLT2 inhibitors vs. non-exendin GLP-1 receptor agonists, according to Srinivasan Beddhu, MD, scientific director at the Cardiovascular, Renal and Metabolism Center, Sydney E. Hartsell, MD, MPH, physician scientist in the division of nephrology and hypertension, both at University of Utah Health, and

Q&A: Navigating new inspiration photos for cosmetic consults: AI-enhanced faces

Clinicians are accustomed to patients bringing celebrity inspiration photos of celebrities to cosmetic consultations. But recent technological advancements have prompted some to show a new type of image: AI-enhanced versions of themselves.
Patients are uploading self-portraits into AI programs and requesting the chatbots make them look younger, more beautiful or enhanced. The aesthetic result is something cosmetic dermatologists and facial plastic surgeons are calling “AI face,” and it is an increasingly common request in the clinic, according to Konstantin Vasyukevich, MD, a private facial

High LDL rising globally while associated mortality falls

The number of adults with elevated LDL increased from 2.5 billion in 1990 to 4.6 billion in 2023, with 6% of all global deaths attributable to high LDL in 2023, according to study findings published in JAMA.
Although age-standardized deaths and disability-adjusted life-years associated with elevated LDL decreased since 1990, the LDL burden shifted and now affects more middle-income countries, researchers reported.
“LDL is one of the most established, modifiable drivers of ASCVD, yet most data track population lipid trends in isolation from actual outcomes,” Christian Razo, PhD, acting assistant

Do weighted vests have a long-term impact on weight loss?

Click here to read the Healio Exclusive, “Not just a fad: The impact of weighted vests on bone health.”
Intentional weight loss presents a clinical dilemma for musculoskeletal providers.
While reducing excess body weight improves overall health and decreases joint loading, it also reduces the mechanical stimulus necessary to maintain bone mass. This is particularly relevant in older adults, who are already at increased risk for osteoporosis and fragility fractures. As a result, there has been growing interest in whether weighted vests can replace some of the lost mechanical loading and help

Nintedanib dry powder inhalation has favorable safety in IPF

Nintedanib dry powder inhalation in patients with idiopathic pulmonary fibrosis was “generally safe” with “a tolerability profile built for chronic use,” according to topline data from a phase 1b study.
“There’s an urgent need for new effective therapies in IPF, and we believe lung targeted delivery is the best approach that addresses the tolerability barriers that are holding today’s therapies back,” Michael Castagna, PharmD, CEO of MannKind Corporation, said during a data readout.
In the multisite, randomized, double-blind, placebo-controlled INFLO-1 phase 1b study, researchers analyzed 27