E-bike crash study links severe brain injuries to older men riding unhelmeted

Since 2023, more e-bikes have been sold in Germany than conventional bicycles. But the number of crashes has been rising just as sharply. Doctors at the Technical University of Munich's TUM University Hospital analyzed patterns in e-bike crashes and found that older men face a particularly high risk of serious injury. The data also revealed clear patterns in the underlying risk factors.

How shift workers’ internal clock affects their health

Health care workers who take on extended or overnight shifts, particularly during periods of operational strain, may face heightened fatigue that can affect their own well-being. This fatigue arises not from individual effort or commitment, but from the physiological challenges created when work demands intersect with the body's internal clock.

Surviving sepsis: New guidelines harness life-saving evidence for treating adults

An international team of experts recently came together to update sepsis care guidelines for adults for the first time since 2021. The updates have profound implications for the management of sepsis, which is responsible for approximately 11 million deaths per year worldwide. Co-led by U-M's Hallie Prescott, M.D. and Massimo Antonelli, M.D. of Catholic University in Rome, Italy, the 69-person panel reviewed research, concentrating on areas of care that may have new evidence supporting a change in practice.

Small RNAs offer new clues to schizophrenia and bipolar disorder

For decades, scientists studying brain disorders have focused almost exclusively on proteins and the genes encoding them. Now, research from Thomas Jefferson University's Computational Medicine Center suggests that several classes of small regulatory molecules, fittingly known as small RNAs, may play a much larger role in schizophrenia and bipolar disorder, and in a healthy brain, than previously thought.