The National Psoriasis Foundation issued a new position statement that clarifies the definition of psoriasis disease severity.
The new criteria define psoriasis severity as “mild” or “moderate to severe.” The update was made to address lingering misconceptions that limit patient access to appropriate care, according to the National Psoriasis Foundation (NPF).
Historically, psoriasis severity was classified as mild, moderate or severe based solely on the percentage of body surface area covered by psoriatic lesions. However, the three-class system underestimated severity of disease when

At ACR Convergence 2025, Cassandra Calabrese, DO, and I were invited to deliver a joint concurrent session with the mischievous and irresistible title, “Fake Rheum.”
Our charge was to explore the architecture and complexity of diagnosis when rheumatologists confront the uncomfortable possibility that what looks like rheumatic disease may, in fact, be something else entirely. These are the kinds of cases that make you stop and think sometimes — in the stairway, or at night when you are trying to rest.
Cassie and I initially envisioned a session built around the anatomy of diagnostic reasoning,

Reductions in measured GFR after bariatric surgery were positively correlated with baseline measured GFR before surgery, according to study data published in the Journal of the American Society of Nephrology.
In addition, the magnitude of weight loss was weakly correlated with change in measured GFR (mGFR) after surgery.
Data on the effect of bariatric surgery on mGFR are limited by small sample sizes and few studies overall, according to Allon N. Friedman, MD, professor of medicine in the division of nephrology at Indiana University, and colleagues. By pooling all available studies of

An autonomous AI-based system may be feasible for determining patients who require early intervention to address cognitive concerns related to Alzheimer’s disease, according to data published in NPJ Digital Medicine.
“This research addresses a growing gap between the rapid aging of the global population and health care systems’ limited capacity to detect early cognitive change,” Lidia Moura, MD, PhD, MPH, study co-author and director of population health and the center for health care intelligence in the department of neurology at Mass General Brigham, told Healio.
“Cognitive screening today

After nonfatal myocardial infarction or stroke, initiation of a GLP-1 receptor agonist was linked to reduced risk for all-cause and CV-related mortality in patients with diabetes, researchers reported.
Despite apparent mortality gains after GLP-1 initiation following a major event, uptake remains low and disparities in use have emerged, according to a study.
Findings from a national study in the Czech Republic evaluating use of GLP-1s after nonfatal MI or stroke in patients with diabetes were published in the European Journal of Preventive Cardiology.
“GLP-1 receptor agonists have

The FDA has accepted an investigational new drug application from a global biotechnology company for its investigational, synthetic psilocybin therapeutic to treat PTSD, according to the manufacturer.
In a press release, Compass Pathways plc said the acceptance will ease the path toward a pending phase 2b/3 clinical trial that aims to examine the safety, efficacy and tolerability of COMP360.
The novel therapeutic was previously granted breakthrough designation from the FDA as well as innovative licensing and access pathway designation in the United Kingdom to address treatment-resistant

Second opinions on cancer treatment plans can save thousands of dollars in health care costs.
A retrospective analysis showed subspecialists who changed care for newly diagnosed multiple myeloma , colorectal, head and neck, and lung cancers decreased costs an average of $15,000 per patient.
“The magnitude of the cost savings, for certain patients, was pretty surprising,” Benjamin R. Roman, MD, MSHP, thyroid and head and neck surgeon at Memorial Sloan Kettering Cancer Center, told Healio.
“We saw patients who had been originally diagnosed with active multiple myeloma. When they came to the second

Adults with obesity and type 2 diabetes who underwent bariatric surgery had greater decreases in HbA1c and body weight than those receiving medical and lifestyle intervention, regardless of social vulnerability, study data showed.
As Healio previously reported, the Alliance of Randomized Trials of Medicine vs. Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) study found adults who underwent bariatric surgery across four randomized trials conducted from May 2007 to August 2013 had larger decreases in HbA1c and body weight at 7 years than adults receiving medical or lifestyle intervention. Use

In patients with cystic fibrosis, CMTX-101, an immune-enabling antibody therapy, lowered four inflammatory biomarkers and Pseudomonas aeruginosa burden vs. standard of care, according to phase 1b/2a trial topline results.
“CMTX-101 could represent an important new tool for those who treat people with [cystic fibrosis (CF)] and other bronchiectatic lung diseases,” David V. Richards, JD, chief executive officer at Clarametyx Biosciences, told Healio.
“While [standard of care] today is effective, there are no solutions that specifically target the biofilm, and we believe this could amplify

After completion of an asthma outreach program in three communities in the Navajo Nation, the odds for routine asthma care visits among children rose, according to results published in The Journal of Allergy and Clinical Immunology: Global.
“Even providers who believe they know how to care for children with asthma reported after the intervention that their adherence to evidence-based guidelines increased following the study,” Bruce G. Bender, PhD, pediatric neuropsychologist and head of the division of pediatric behavioral health at National Jewish Health, told Healio.
“Training in asthma