A stable sense of purpose helps teens navigate life’s challenges

Like their emotions and self-esteem, teenagers' sense of purpose fluctuates day to day, and those who experience it steadily—not just intensely—may benefit most, new Cornell research finds. Studying the phenomenon in adolescents for the first time, the research adds to an emerging understanding that purpose is not a constant, have-it-or-you-don't trait measurable at any one time, as implied by most research to date.

AI model can predict chemotherapy benefit in breast cancer

Deciding whether to administer chemotherapy after surgery is one of the most challenging questions in early-stage breast cancer care. While chemotherapy can reduce the risk of recurrence, most patients do not benefit from it and may experience significant short- and long-term side effects. The central challenge is identifying, at the time of diagnosis, which patients are likely to benefit and which are not.

Not just boys: The overlooked story of ADHD in women and girls

When people think about attention-deficit/hyperactivity disorder (ADHD), they often picture a hyperactive young boy running around a classroom, not the quiet girl daydreaming in the corner, the chatty student who can't finish her work or the mother who is chronically late and constantly searching for her keys.

Natural competition between brain circuits may boost information processing

Over the past decades, neuroscience studies have painted an increasingly detailed picture of the human brain, its organization and how it supports various functions. To plan and execute desired behaviors in changing circumstances, networks of neurons in the brain can either work together or suppress each other, thus employing both cooperative and competitive interaction strategies.

Solving the oxygen problem in cell-based drug delivery

Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping the cells alive and thriving. Researchers at Rice University and collaborators at Carnegie Mellon University and Northwestern University have now successfully integrated solutions to several persistent challenges to implantable drug factories into a single device. According to a new study, the Hybrid Oxygenation Bioelectronics system for Implanted Therapy, or HOBIT, shields a sufficient number of cells from the host immune system in a comfortably small volume while also providing access to oxygen and nutrients.