Researchers finally report some good news on endometriosis

This year, International Women's Day coincides with Endometriosis Awareness Month. Endometriosis is a common and painful gynecological disease that impacts 14% of women and girls across the world—currently, there is no long-term cure. Finding new treatments for endometriosis is now more critical than ever.

Mutant group B strep strains may explain infections in newborns

A new study could explain why some mothers can still pass Group B Streptococcus, or GBS, to their babies after childbirth even when they're treated with antibiotics. A Michigan State University research team discovered postpartum GBS strains with mutations that allow them to survive in the birth canal and resist treatment. These strains can infect newborns and infants and cause dangerous illnesses like pneumonia, meningitis and sepsis.

Why a better-performing developing brain may be a better-tuned brain

An influential hypothesis in neuroscience is that the brain may operate near criticality, a transition zone between subcritical dynamics, associated with excessive inhibition, and super-critical dynamics, associated with excessive excitability. In preclinical and computational studies, activity near this regime has been linked to efficient information processing and adaptive responsiveness to input.

Testosterone improves fat distribution for older women

As we age, the amount and distribution of fat in our bodies changes. Most fat is subcutaneous—meaning it is stored just under the skin. Subcutaneous fat generally does not have detrimental health impacts. In fact, we need some amount of fat to be healthy. Visceral fat, however, is stored in the gut and has been linked to negative health impacts, including diabetes and cardiovascular disease.

Discovery might inform new approach to Huntington’s disease

Treatments that target a fragment of the mutant protein that causes Huntington's disease might be more effective than treatments—now in clinical trials—that target the whole protein but leave this fragment intact, a new study in mice suggests. The findings appear in Science Translational Medicine.