The FDA has approved Johnson & Johnson’s supplemental new drug application for Caplyta among patients with schizophrenia at risk for relapse, according to a press release from the company.
Noting that schizophrenia affects approximately 2.8 million adults in the United States, with a total cost of $366.8 billion in 2024, Johnson & Johnson said approximately 40% of patients do not receive adequate care.
Relapse remains “one of the most critical challenges” for patients with schizophrenia, Leighann Forbes, MS, PhD, vice president, U.S. neuroscience medical affairs, Johnson & Johnson,

Among postmenopausal women, higher Life’s Essential 8 and Life’s Crucial 9 scores were associated with a lower risk for mortality, according to an association analysis study in Menopause.
The risk for cardiovascular morbidity and mortality increases in postmenopausal women because of hormonal changes, metabolic alterations and vascular aging, research shows. American Heart Association’s Life’s Essential 8 (LE8) and Life’s Crucial 9 (LC9) scores give an overview of an individual’s cardiovascular health, with LC9 incorporating measures of psychosocial health.

State health officials said Monday that the measles outbreak that sickened nearly 1,000 people in South Carolina has ended.
Measles outbreaks are considered over if there are no new cases within 42 days — the maximum length of two incubation periods for the measles virus. Sunday marked 42 days since the last confirmed case was reported on March 15.
Overall, there were 997 cases confirmed in the outbreak since last October. Cases were reported in seven counties, but 940 occurred in Spartanburg County in the upstate region.
“Though we reached nearly 1,000 cases, we are grateful that, by and large,

A proprietary extended-release oral minoxidil tablet yielded rapid and robust hair growth in men with pattern hair loss, according to topline results.
Data from study 302, a phase 2/3 trial including more than 500 men with androgenic alopecia, suggest VDPHL01 (Veradermics) could potentially become the first FDA-approved oral pill for pattern hair loss in nearly 30 years and the only non-hormonal option, the company stated in the release.
“We are optimistic that these results represent a defining milestone for the hair loss community, our company and investors as we advance this foundational,

An enhanced monofocal IOL provided useful near and intermediate vision and “excellent” distance vision, according to a study published in Journal of Refractive Surgery.
Marcela Feltrin de Barros, MD, and colleagues wrote that while monofocal IOLs remain the standard of care for most patients, limitations to intermediate vision leave patients with a desire for better outcomes.
“The rapidly increasing use of handheld devices, mobile phones and computers in everyday life has elevated the patient’s desire to achieve better intermediate vision after cataract surgery,” they wrote. “As such, IOL

Nearly 15% of acute coronary syndromes in Northern California are methamphetamine-related, which remains a strong predictor of poor survival in a population of predominantly young men, researchers reported.
Despite lower levels of traditional risk factors such as diabetes and obesity, patients with methamphetamine-associated ACS experience significantly higher rates of all-cause mortality compared with nonusers with ACS, according to data published in the Journal of the American Heart Association.
“The key takeaway for my cardiology colleagues is the need for heightened awareness of the strong

LAS VEGAS — Insulin pump use during hospitalization may improve glycemic outcomes and reduce length of stay for people with diabetes, according to a presenter.
During a talk at the American Association of Clinical Endocrinology Annual Scientific and Clinical Conference, Alaa Almallouhi, MD, a second-year resident at Naples Comprehensive Health in Florida, presented data on adults using an insulin pump who were admitted for inpatient hospitalization. Almallouhi said the study was important to conduct due to the increased use of insulin pumps in outpatient settings.
“Many hospitalized patients

In patients with persistent atrial fibrillation, those receiving pulsed field ablation as first-line therapy had less risk for recurrent atrial arrhythmias than those receiving drug therapy, researchers reported at Heart Rhythm 2026.
For the AVANT GUARD trial, simultaneously published in The New England Journal of Medicine, Oussama M. Wazni, MD, MBA, section head of cardiac electrophysiology and pacing, director of the outpatient electrophysiology department and codirector of the Ventricular Arrhythmia Center, Center for Atrial Fibrillation and the Atrial Fibrillation Stroke Prevention Center

There were no major differences among neurologic patients when seen virtually or in-person for their first visit, with similar 90-day follow-up, ED visits and hospitalizations, according to a study published in Neurology.
“We wanted to understand the impact of virtual visits on clinical outcomes and to consider if some neurologic patients might be better served by an initial in-person visit rather than a virtual visit,” Chloe Hill, MD, MS, assistant professor of neurology at the University of Michigan Medical School, told Healio.
The retrospective multicenter cohort study included 10,428

Cost and quality-adjusted life years of alpha-gal IgE screening vs. not screening in asymptomatic patients suggest that screening is not cost-effective to prevent fatal anaphylaxis, according to study findings.
These data were published in The Journal of Allergy and Clinical Immunology: In Practice.
“I think the analysis matters to both clinicians and patients because while the test is easy to send, in regions where prevalence of sensitization (but not anaphylaxis) is high, it will likely cause more problems than it solves,” Marcus Shaker, MD, MSc, FAAP, FACAAI, FAAAAI, professor of pediatrics