Off-prescription Adderall increases blood pressure, heart rate

Adderall significantly increased BP and heart rate among healthy young adults who never previously used the medication, simulating its effects among those who may abuse it recreationally, researchers reported.
Adderall — a combination of amphetamine-dextroamphetamine salts — may have CV effects not previously documented, but the long-term safety of the medication cannot be extrapolated from this data, according to the results of a randomized, double-blind, placebo-controlled study published in Mayo Clinic Proceedings.
“While Adderall is a schedule II drug and requires a prescription, an

Ultraprocessed foods linked to adverse behavior in preschoolers

Anxiety, aggression, hyperactivity and other adverse behaviors in preschoolers were associated with higher intake of ultraprocessed foods, a study in JAMA Network Open found.
“In a large Canadian birth cohort, we observed that higher consumption of ultraprocessed foods at age 3 was associated with slightly higher scores for internalizing and externalizing behavioral difficulties at age 5,” principal investigator Kozeta Miliku, MD, PhD, assistant professor of nutrition sciences at the University of Toronto, told Healio.
In Canada, ultraprocessed foods account for nearly half of the

Specialists navigate challenging landscape of geographic atrophy

Click here to read the Point/Counter to this Cover Story.
The introduction of the first disease-modifying therapies fundamentally transformed the management of geographic atrophy and brought new changes and challenges in clinical practice, workflow and capacity.
The FDA approved complement inhibitors Syfovre (pegcetacoplan injection, Apellis) and Izervay (avacincaptad pegol intravitreal solution, Astellas) in 2023, and since then, the approach to managing intermediate age-related macular degeneration has shifted from solely using oral supplements and observation to the possibility of actively

Automated insulin delivery may expedite basal insulin dose titration in type 2 diabetes

Automated insulin delivery may be used as a temporary tool to determine the proper basal insulin dosing for adults with type 2 diabetes, according to a speaker.
At the International Conference on Advanced Technologies & Treatments for Diabetes, Heman Shakeri, PhD, assistant professor at the University of Virginia School of Data Science, presented findings from a small pilot study that showed adults with type 2 diabetes using the Control-IQ automated insulin delivery system (Tandem Diabetes Care) for 10 days to titrate basal insulin reached similar glycemic outcomes as those using a

Sleep coaching in obesity care: A clinical tool for better outcomes

As obesity medicine continues to evolve, integrating sleep health into obesity treatment plans is essential.
Poor sleep quality and undiagnosed sleep disorders are frequently overlooked contributors to weight gain, treatment resistance and chronic disease. For patients with obesity, sleep coaching offers a valuable tool that can enhance outcomes and support lasting change.
Obstructive sleep apnea is a common condition in patients with obesity, involving the complete or partial obstruction of the upper airway, which leads to lack of restorative sleep due to reduced oxygenation. These disruptions

No conclusion found in sibling study for ADHD, ASD, acetaminophen

A sibling-matched study design analyzing a cohort of more than 2 million singleton births was found to be inconclusive in determining if maternal acetaminophen use during pregnancy impacts offspring neurodevelopment, according to published data.
More specifically, the JAMA Pediatrics study by Zeyan Liew, PhD, MPH, associate professor of epidemiology at Yale School of Public Health, and colleagues investigated the connection of maternal acetaminophen use and diagnoses of ADHD and autism spectrum disorder (ASD) in offspring.
While associations between acetaminophen exposure in utero and the

Q&A: ‘Exergaming’ feasible for children, adolescents on dialysis

An “exergaming” system that combines exercise and video gaming could promote physical activity while children and adolescents receive in-center hemodialysis, according to study data published in Pediatric Nephrology.
Few studies have explored sports or exercise-based interventions during in-center hemodialysis, according to Marleen Kerstin, Lene Stegelmann and other researchers at the Institute of Cardiology and Sports Medicine at German Sport University Cologne. Thus, the researchers collaborated with Icaros, a Germany-based company developing exergaming devices that created a “wobble

Objective cough monitoring valuable, needs real-world validation

When monitoring cough, both subjective and objective measures are needed, but use of objective cough counting tools is lacking in clinical practice, according to a scoping review published in Lancet Digital Health.
In the review, researchers found and analyzed studies covering stationary, portable and modern digital monitors for objective cough counting in patients with asthma, COPD, tuberculosis, COVID-19 and other respiratory diseases to uncover how these tools are used in patient care and public health, how objective cough frequency is linked to patient-reported outcomes (PROs) and what

Vaccinated vs. naturally infected people lose measles protection

PHILADELPHIA — A larger proportion of individuals previously vaccinated for measles vs. those with natural infection had seronegativity, according to data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
“From our study, there should be increased surveillance of measles serologies because this will tease out people who have the negative serologies and should be revaccinated, especially since the measles infection is so contagious and we’re going to have accidental exposures,” Alison Chen, BA, medical scribe at The Asthma Center in Philadelphia, told Healio.

Proximity to nuclear plants may affect cancer mortality risk

U.S. counties located closer to nuclear power plants have higher cancer mortality rates than those located farther away, results of a national analysis showed.
The study — which accounted for environmental, socioeconomic and other factors — yielded results that remained consistent through multiple sensitivity analyses.
In light of increased attention on nuclear power as a low-carbon energy alternative, more research into its potential effects on public health is warranted, according to Yazan Alwadi, PhD, postdoctoral research fellow in the department of environmental health at Harvard T.H. Chan