Children and adults with type 1 diabetes who used a fast-acting mealtime insulin along with automated insulin delivery had improvements in time in range and other continuous glucose monitoring metrics, according to study data.
In a single-arm clinical trial published in Diabetes Technology & Therapeutics, researchers assessed glycemic outcomes for people with type 1 diabetes using ultra-rapid insulin lispro-aabc (Lyumjev, Eli Lilly) with the Medtronic MiniMed 780G automated insulin delivery system. During the trial’s final 6 weeks, both children and adults had improvements in time in range

For years, the relationship between cannabis smoking and lung cancer has been described as unclear or conflicting.
Now, a large retrospective cohort study by Gallagher et al, published in Lung Cancer in April, challenges that narrative.
Using 20 years of electronic medical record data from 67 U.S. health care organizations and propensity score-matched cohorts of nearly 150,000 individuals per group, the study found that adults with cannabis use disorder had a nearly four-fold increased risk for developing lung cancer (RR = 3.87; 95% CI 3.43-4.38).
The elevated risk was consistent across

Modifiable risk factors such as alcohol consumption, BMI, dietary patterns and smoking could shift cancer risk as much as 60% for certain malignancies.
Incorporating these risk factors into “cookie-cutter” screening guidelines could personalize detection and identify a wide swath of the at-risk population that currently is overlooked, Neel M. Butala, MD, assistant professor of medicine at University of Colorado Anschutz, told Healio.
Nearly 30% of men and more than 20% of women are at risk for developing cancer during their lifetime, but lifestyle changes could dramatically lower this risk,

The risk for major adverse cardiovascular events appeared similar between older patients treated with 5-aminosalicylic acid and those who received immunomodulators or biologics for inflammatory bowel disease, data show.
“Our findings are reassuring in that immunomodulators and biologics were not associated with elevated cardiovascular risk,” Tianze Jiao, PhD, assistant professor in the department of pharmaceutical outcomes and policy at the University of Florida, told Healio.
“This [research] supports consideration of these therapies when clinically indicated, without substantial concern for

Patients with systemic autoimmune rheumatic disease demonstrate an increased persistence of SARS-CoV-2 antigen positivity up to 6 months after COVID-19 infection, according to data published in Arthritis & Rheumatology.
“Longer duration of SARS-CoV-2 antigen persistence in the blood has been associated with various outcomes including higher risk of post-acute sequelae of COVID-19,” Naomi J. Patel, MD, MPH, from the division of rheumatology, inflammation and immunity at Mass General Brigham, told Healio. “Individuals with systemic autoimmune rheumatic diseases (SARDs) are