If Medicaid work requirements enacted in the One Big Beautiful Bill Act are expanded nationwide, about half of adult beneficiaries could lose their coverage, according to experts.
Because of the law, signed by President Donald J. Trump in July 2025, federal support for Medicaid will be cut by $930 billion over the next decade. Plus, for the first time in the program’s nearly 60-year history, certain able-bodied adults aged 19 years to 64 years will be required to work, participate in job training, volunteer or enroll in school at least 80 hours a month to maintain their Medicaid

The FDA approved Radiesse for the treatment of wrinkles in the décolleté area for patients aged 22 years and older, despite breast cancer screening concerns, according to a press release.
Radiesse (Merz Aesthetics) is a sterile, non-pyrogenic, semi-solid, cohesive implant comprised of 30% synthetic calcium hydroxylapatite and 70% carrier gel. In 2024, Radiesse was approved in the European Union for the treatment of wrinkles in the décolleté area after FDA approvals in 2006 and 2015 for facial wrinkles/folds and volume loss in the hands.
Due to the radiopaque nature of the microspheres in the

NEW ORLEANS — In patients with post- and precapillary pulmonary hypertension and heart failure with preserved ejection fraction, sotatercept improved hemodynamics, according to the results of the CADENCE trial.
“Patients with heart failure with preserved ejection fraction have problems in which the heart’s left ventricle doesn’t relax fully, and may be stiff,” Mardi Gomberg-Maitland, MD, MSc, cardiologist and professor of medicine at the George Washington School of Medicine and Health Sciences, said during a press conference. “Some people with HFpEF develop high pressure in their lungs caused

In this video from the Macula Society meeting, Sunir J. Garg, MD, FACS, FASRS, discusses research concerning the development and progression of geographic atrophy.
“The hypothesis is ... maybe all geographic atrophy isn’t the same, and maybe different combinations of oxidative risk factors or complement inhibition may play different roles in the lifetime of geographic atrophy progression,” according to Garg, of the retina service at Wills Eye Hospital.
Further research into this idea could improve personalized treatment of geographic atrophy, Garg said.

SAN DIEGO — Semaglutide 25 mg tablets were tied to significantly greater mean weight loss vs. orforglipron 36 mg tablets, according to data presented at the Obesity Medicine Association’s annual conference.
Orforglipron (Foundayo, Eli Lilly) was also associated with around four to 14 times higher odds of treatment discontinuation due to adverse effects compared with semaglutide (Wegovy, Novo Nordisk), according to a Novo Nordisk press release.
The data “add to the growing body of evidence supporting the clinical strength of semaglutide and highlight attributes that patients value when choosing

In this video from the Macula Society meeting, Sunir J. Garg, MD, FACS, FASRS, discusses the impact of lifestyle changes on the development of geographic atrophy in people with high genetic risk.
“Even if a person is genetically susceptible to developing AMD, you can reduce your risk of developing advanced AMD by about 55% to 60% by lifestyle modifications,” Garg, of the retina service at Wills Eye Hospital, said.
These modifications include changes to diet and smoking habits, according to Garg.

In this video from the Macula Society meeting, Sunir J. Garg, MD, FACS, FASRS, of the retina service at Wills Eye Hospital, discusses 5-year fellow eye data on pegcetacoplan for geographic atrophy.
“We found that if you use sham or projected sham, treatment with pegcetacoplan (Apellis) reduces disease progression by about 25% in the all-comer group,” Garg said. “That was even more significant if you look at patients who had baseline nonsubfoveal atrophy.”
In addition, the fellow eye “almost mirrored sham precisely,” confirming that “two eyes and

A behavioral intervention focused on fluid intake did not significantly reduce kidney stone recurrence, but did increase 24-hour urine output, according to study data published in The Lancet.
Recurrence rates for kidney stones are about 50% at 3 years for children and adolescents and about 20% at 5 years for adults, with some estimates higher, according to Charles D. Scales Jr., MD, MSHS, FACS, associate professor of urology and population health science at Duke University School of Medicine. Maintaining high water intake can be a safe and effective preventive measure against kidney stone

Historically, osteochondral lesions of the talus were treated with debridement with or without bone marrow stimulation techniques.
However, data published in 2023 from Xiangyun Cheng, PhD, and colleagues showed there are certain circumstances in which bone marrow stimulation is not the ideal indication to treat osteochondral lesions of the talus. In a retrospective study evaluating 82 patients who underwent bone marrow stimulation on lesions less than 100 mm² in size, Cheng and colleagues found lesions with an area greater than 90.91 mm², depth greater than 7.56 mm and volume greater than

CHICAGO — In recent years, efforts to interrogate established medical practices rooted in sometimes decades-old dogma have led to shifts in how some patients are treated.
In infectious diseases, this has been especially true in the use of antimicrobials, with experts revisiting some of the what, when and for how long of established prescribing guidelines.
Those efforts — always with an eye on balancing stewardship and patient health — have helped reshape popular opinions on prescribing durations for some infections and whether IV-only therapy is needed for others.
Findings from a small