EyeSustain, industry collaborate to reduce waste

Before EyeSustain, sustainability efforts in ophthalmology were fragmented and isolated.
That is what David F. Chang, MD, told Healio | OSN in the weeks following the organization’s founding in 2022. Now in its fourth year, EyeSustain has grown from its three initial sponsors — the American Society of Cataract and Refractive Surgery, the European Society of Cataract and Refractive Surgeons, and the American Academy of Ophthalmology — to 58 ophthalmology member societies across the globe.
Chang, a Healio | OSN Cataract Surgery Board Member, said that when he thinks about the scale of ophthalmic

Process to add new layers of heart muscle may help in HF

In an early study, a tissue-engineered heart muscle product was linked to improvements in heart wall thickness, left ventricular ejection fraction and quality of life in patients with heart failure with reduced EF.
Biologic ventricular assist tissue (Repairon) is “the first tissue-engineered heart muscle product in clinical trials” and the phase 1 to 2 BioVAT-HF study, published in The New England Journal of Medicine, is the “first approach testing remuscularization by cardiomyocyte transplantation supported by concomitant immunosuppression to ensure long-term retention as therapeutic

More patients with cancer being hospitalized for alcohol use

CHICAGO — Alcohol-related admissions account for less than 1% of unplanned hospitalizations among patients with cancer, but incidence has significantly increased over time.
Data presented at ASCO Annual Meeting showed an average annual increase of almost 200 alcohol-related hospitalizations among adults with cancer between 2016 and 2021.
“This is an alarming upward trend,” Anna Mehlich, MD, internist at John H. Stroger Jr. Hospital of Cook County, told Healio.
Previous research has shown that alcohol consumption has a causal link with multiple malignancies, including breast, colorectal,

Beneath the Surface: What to look for on a sunscreen label

U.S. consumers are often faced with a confusing number of sunscreen ingredients to decipher. Knowing what to look for in a sunscreen formulation is important when choosing a sun protection product.
In this Beneath the Surface video interview, Joel M. Gelfand, MD, MSCE, FAAD, the James J. Leyden Professor of Clinical Investigation and professor of dermatology and epidemiology at University of Pennsylvania’s Perelman School of Medicine and Healio Dermatology’s Chief Medical Editor, spoke with Adewole S. Adamson, MD, MPP, a dermatologist and health services researcher at Dell Medical School at

Abemaciclib may be new standard for sarcoma subtype

CHICAGO — Abemaciclib significantly prolonged PFS compared with placebo for patients with advanced dedifferentiated liposarcoma, according to findings presented during ASCO Annual Meeting’s plenary session.
Results of the randomized phase 3 SARC041 trial — the first-ever positive phase 3 trial in dedifferentiated sarcoma — showed a trend toward longer OS with the agent, supporting its use as a treatment option in this setting.
“That will be something for the community to discuss as they evaluate the data, as this was not designed as a registration study,” lead study author Mark A. Dickson, MD,

What to know about vaccination for patients with kidney disease

The National Kidney Foundation created a multidisciplinary working group to develop recommendations for improving vaccination care among patients with chronic kidney disease.
In a special report published in the American Journal of Kidney Diseases, members of the Improving Vaccination in CKD Working Group outlined recommendations focused on improving vaccination rates, vaccine effectiveness and health care for populations with CKD. Recommendations were included if they received an endorsement rate of 75% or greater in Delphi voting.
Overall, recommendations spanned 12 categories for

Q&A: Practical strategies to reduce hypoglycemia risk

In this Diabetes in Real Life column, Susan Weiner, MS, RDN, CDN, CDCES, FADCES, talks with Mary-Elizabeth Patti, MD, and Sean M. Brown, MD, about recognition of hypoglycemia risk factors and implementation of prevention strategies.
Weiner: How should clinicians differentiate between mild, moderate and severe hypoglycemia in both clinical documentation and patient education?
Patti and Brown: Hypoglycemia is categorized as level 1 (mild; glucose

OSA control remains 1 year after stopping positional therapy

ORLANDO — Nearly 70% of patients with positional obstructive sleep apnea who discontinued positional therapy after achieving disease control still had control at 1 year, according to findings presented here.
“These findings support a more personalized approach to OSA,” Irene Cano-Pumarega, MD, PhD, pneumonologist and head of the sleep unit at Ramόn y Cajal Hospital in Madrid, told Healio about the data presented at the American Thoracic Society International Conference.
“For clinicians, positional therapy could represent a well-tolerated first-line option for selected patients with

Mepolizumab/benralizumab to depemokimab safe in severe asthma

ORLANDO — Both patients with asthma who switched from mepolizumab/benralizumab to depemokimab and patients who continued mepolizumab/benralizumab had low annualized exacerbation rates, according to results presented here.
Depemokimab (Exdensur, GSK) is given twice a year since it is the first ultra-long-acting anti-IL-5 therapy, according to the presentation given at the American Thoracic Society International Conference.
“This is really the first of its kind switch trial, switching patients from being well controlled on a short-acting biologic to an ultra-long-acting biologic in a very

Greater incidence, risk for new mental health conditions in PAH

ORLANDO — Adults with vs. without pulmonary arterial hypertension had a significantly heightened risk for developing a new mental health condition in the 12 months following diagnosis, according to a poster presented here.
“The study results underscore the importance of multidisciplinary care and dedicated mental health support for patients with pulmonary arterial hypertension (PAH),” Anna Watzker, MHS, director of global outcomes research at Merck, told Healio.
“It’s important to be aware that patients with PAH may be at an increased risk of developing a wide range of mental health conditions,