Eczema not linked with worse childhood academic performance

Eczema was not associated with worse academic performance among adolescents, according to an analysis of two population-based cohort studies published in JAMA Dermatology.
The researchers compared the grades of children aged 16 years who took national compulsory examinations in Denmark and England and found that there was no meaningful difference between the scores of adolescents with eczema and those without.
“Atopic dermatitis, or eczema, can affect many parts of a child’s daily life. It can interfere with sleep, concentration and emotional well-being, so it is understandable that families

Daily multivitamins might slow biological aging in older adults

Two years of daily multivitamin use was associated with slower biological aging compared with placebo in older adults, particularly those with prematurely aged epigenetic clocks, according to a study in Nature Medicine.
The research team drew data from the randomized, double-blind and placebo-controlled COcoa Supplement and Multivitamin Outcomes Study (COSMOS).
“A lot of people take a multivitamin without necessarily knowing any benefits from taking it, so the more we can learn about its potential health benefits, the better,” senior author Howard D. Sesso, ScD, MPH, associate director of the

Early biologic therapy reduces progression in ulcerative colitis

Biologic therapy within a year of diagnosis could decrease risk for disease progression among patients with ulcerative colitis.
A retrospective analysis of more than 200 adults with UC found those who did not receive treatment early in the disease course had nearly five times the risk for progression and colonic structural damage.
“This study is highly innovative and may help reshape the concept of the window of opportunity in ulcerative colitis,” Joana Camoes Neves, MD, physician specializing in gastroenterology at Hospital de Braga in Portugal, told Healio.
“From a clinical perspective, we did

Targeting APOC3 may not prevent coronary plaque progression

NEW ORLEANS — Monthly olezarsen reduced triglycerides and apolipoprotein B in patients with hypertriglyceridemia but may have no impact on coronary plaque progression at 1 year, a speaker reported.
Olezarsen (Tryngolza, Ionis Pharmaceuticals), an antisense oligonucleotide designed to target apolipoprotein C-III messenger RNA, may also have no impact on low-attenuation, calcified or total plaque volume in patients with moderate hypertriglyceridemia at CV risk or those with severe hypertriglyceridemia, according to results of the Essence-TIMI 73b Imaging Study presented at the American

High vitamin D levels in midlife associated with lower tau protein in older adults

High vitamin D levels in mid-life were associated with lower levels of tau protein in the brain more than a decade later, suggesting a possible modifiable risk factor for Alzheimer’s disease, according to findings in Neurology Open Access.
“Previously, it was known that low circulating vitamin D in later life is associated with an increased risk of cognitive impairment and clinical dementia,” Martin D. Mulligan, MBBCh, BAO, a researcher at the University of Galway in Ireland, told Healio.
“Most prior studies evaluating the association between vitamin D and cognitive function typically measured

VIDEO: Sunshine Eye highlights evolution of neurotrophic keratitis awareness, treatment

MIAMI — In this video from Sunshine Eye & Retina, Kendall E. Donaldson, MD, MS, of Bascom Palmer Eye Institute, discusses the evolution of awareness and treatment of neurotrophic keratitis.
Donaldson highlighted available treatment options and the importance of checking corneal sensation and trying to introduce early treatment.
“The main point here at the meeting has been that we just have so many options, and for a lot of these patients, we need to do multiple things to help them down the pathway, but ... intervening early in the course can be so much more helpful,”

Natural cures common allergy misinformation theme on social media

Across TikTok, Instagram, Facebook and X, posts containing allergy misinformation often promoted natural cures and endorsed IgG testing, according to data published in The Journal of Allergy and Clinical Immunology: In Practice.
“Patients are coming to clinic with preconceived ideas and goals, sometimes based on incorrect narratives,” Samira Jeimy, MD, PhD, FRCPC, associate professor at Western University in Canada, told Healio. “Our task as physicians has expanded accordingly. We now not only diagnose and treat but engage with those narratives and rebuild understanding without losing trust.

Sooner not better for CDK4/6 inhibitors in advanced breast cancer

As clinicians celebrated results of the PALOMA-2 study at ASCO Annual Meeting in 2016, Gabe S. Sonke, MD, PhD, had a question.
In PALOMA-2, women with advanced breast cancer who received first-line palbociclib (Ibrance, Pfizer) plus letrozole (Femara, Novartis) had a 42% lower risk for disease progression or death than those who received letrozole alone.
Sonke described the results as “impressive,” but also not surprising.
“I knew the hazard ratio already because the previous year, the second-line study was presented with exactly the same hazard ratio,” Sonke, head of the division of medical

Medicare coverage of rheumatoid arthritis drugs ‘restrictive’

Patients with Medicare Part D insurance plans experience uneven and “restrictive” coverage of certain drugs and drug classes used to treat rheumatoid arthritis, according to data published in Arthritis & Rheumatology.
“We were motivated to study this topic when we observed that Medicare Part D plans — which administer the prescription drug benefit — were narrowing the scope of their formulary coverage in recent years,” Youngmin Kwon, PhD, of the department of health policy at Vanderbilt University Medical Center, told Healio. “Formulary exclusions

New primary care campaign seeks to cut benzodiazepine overuse with reviews and patient support

The widespread use of benzodiazepines—better known as sleeping pills or anxiety medication—among the population has become a serious public health issue. These psychotropic drugs, central nervous system depressants prescribed to treat anxiety and insomnia, carry a high risk of dependence, cognitive impairment and falls, among other consequences. A 2024 study carried out by the Spanish Organization of Consumers and Users (OCU) showed that 22% of the Spanish population regularly use this type of medication, in four out of ten cases on a daily basis.