Omalizumab helps patients tolerate full servings of allergens

Among patients with multiple food allergies treated with omalizumab, 36% achieved a cumulative tolerated dose of at least 4,044 mg for three foods by the end of treatment, according to results published in JAMA Pediatrics.
Compared with patients receiving omalizumab-facilitated multiallergen oral immunotherapy (MOIT), a greater or similar proportion of patients receiving omalizumab reached this level of tolerance depending on the assessed population, according to researchers.
“We have demonstrated that there are multiple paths to living a safe life with food allergies,” Sharon Chinthrajah MD,

Study shows slower reading, fixation alterations in glaucoma

Patients with glaucoma displayed impaired reading performance and increased saccades, according to a cross-sectional study published in Journal of Glaucoma.
“The ability to read is essential for many aspects of daily living, including work-related activities, driving and shopping,” Mariana Chiba Ikeda, MD, of Federal University of São Paulo, and colleagues, wrote. ”... With the growing reliance on computers, smartphones and tablets, reading has become indispensable for online banking, managing household utility bills, insurance, entertainment and communication.”
Ikeda

Dupilumab improves height, bone density for children with eczema

Dupilumab treatment was associated with improved bone growth and bone mineral density in children with eczema, according to a study published in the Journal of the American Academy of Dermatology.
Among children aged 6 to 11 years who were below the 40th height percentile at baseline, 31.3% saw a 5 or greater percentile increase 16 weeks after initiating dupilumab (Dupixent; Sanofi, Regeneron). This proportion grew to 50.7% by week 52, researchers reported.
“Children with severe atopic dermatitis are often behind on their growth trajectories, sometimes to a large degree,” Alan Irvine, MD, DSc,

ADHD drugs have similar effects, differences in weight loss

Dexamphetamine and methylphenidate were equally effective in treating the core features of ADHD in children, but participants taking dexamphetamine were likely to lose more weight, according to a study.
The study, published in the Journal of Paediatrics and Child Health, set out to examine each medication’s effect on inattentiveness and oppositional defiant disorder, said Alison Poulton, MD, FRACP, senior lecturer in pediatrics and child health at the Nepean Clinical School at the University of Sydney.
The findings are pertinent given the rise of obesity, Poulton told Healio.
“Dexamphetamine

Tanruprubart improves muscle strength, health outcomes

In patients with Guillain-Barré syndrome, tanruprubart yielded significant improvements in muscle strength, with patients more likely to functionally recover compared with a placebo group, according to researchers with Annexon Biosciences.
The results of the clinical trial, presented at the 2026 European Academy of Neurology Congress, showed patients treated with tanruprubart (ANX005, Annexon Biosciences), an investigational targeted immunotherapy, walked independently a median of 31 days earlier than the placebo group, said Henk-André Kroon, MD, MBA, head of translational medicine with

Cholecystectomy reduces recurrence risk for gallstone pancreatitis

Same-admission cholecystectomy was linked to lower risk for disease recurrence and gallstone-related complications in patients with mild gallstone-related acute pancreatitis who are fit for surgery, according to population-based study results.
Findings also showed that patients who underwent endoscopic retrograde cholangiopancreatography had lower risk for recurrent disease over time, but were at greater risk for other gallstone-related complications, including acute cholecystitis and choledocholithiasis.
Although guidelines recommend same-admission cholecystectomy for mild gallstone-related

Most adults with diabetes non-covered under insulin caps

State legislation that caps out-of-pocket insulin costs for people with diabetes does not cover most Americans with the disease, according to findings published in Diabetes Care.
In an analysis of out-of-pocket insulin caps that went into effect from 2019 to 2026, researchers found that 29 states and Washington, D.C., have some form of a cap in place. Those caps cover a combined 991,370 adults with diabetes across the U.S., whereas 2,914,293 adults with diabetes are not covered under an insulin cap.
“What our study found is that state-level caps are important, but are definitely not enough,”

Duodenal mucosal resurfacing helps maintain weight loss 1 year after tirzepatide treatment

A duodenal mucosal resurfacing procedure may help adults with obesity maintain weight loss 1 year after discontinuing obesity pharmacotherapy, according to topline results from the REMAIN-1 midpoint cohort.
The Revita (Fractyl Health) duodenal mucosal resurfacing (DMR) system is an endoscopic procedure that remodels duodenal lining to restore healthy nutrient sensing and signaling disrupted by chronic metabolic disease, according to a press release from the company. As Healio previously reported from Digestive Disease Week, adults who underwent a sham procedure in the REMAIN-1 trial regained

Planetary health diet lowers CVD risk in older women

NATIONAL HARBOR, Md. — Greater adherence to the planetary health diet lowered the risk for adverse cardiovascular events in postmenopausal women, a study shows.
“CVD risk increases with age and becomes particularly important after menopause. At the same time, there is growing interest in dietary patterns that may support both human and planetary health,” Donya Shahamati, a PhD student at University of California, Irvine, told Healio. “We wanted to examine whether greater adherence to the planetary health diet was associated with a lower risk of CVD among postmenopausal women.”
The planetary

How kidney transplant failure feels for patients, care partners

Patients and their care partners cited kidney transplant failure as an event that felt “inevitable” yet “surprising,” according to study data.
Kidney transplant failure occurs when a kidney transplant recipient is expected to need dialysis, retransplantation or conservative kidney management within 1 year, according to Pippa Bailey, PhD, professor of renal medicine at Bristol Medical School in the United Kingdom, and colleagues. However, perspectives about the transition from kidney transplant failure to another kidney replacement therapy option have been underreported in qualitative studies,