The FDA approved Lumvoa, a full insulin-like growth factor 1 receptor antagonist, for the treatment of thyroid eye disease, according to a press release from Viridian Therapeutics.
The approval was supported by data from the phase 3 THRIVE and THRIVE-2 pivotal clinical trials, which investigated Lumvoa (veligrotug-vvze, 500 mg) for active and chronic thyroid eye disease (TED), respectively. In both trials, in which patients received a 12-week treatment course, Lumvoa demonstrated “a rapid onset of clinical benefit,” including a reduction in proptosis as early as 3 weeks. Both trials met their

A Duke University study showed that more than half of emergency medical service ambulances and about two-thirds of EMS clinicians harbor clinically important bacteria before and after work shifts.
The study confirmed the researchers’ expectations regarding high vehicle contamination while uncovering an unexpected trend of bacterial loads on clinicians, Diego Schaps, MD, MPH, a resident physician at Duke University Medical Center and former EMS ambulance clinician, told Healio.
“We anticipated there would be a high degree of ambulance contamination," Schaps said. “It was

PARK CITY, Utah — When an extreme athlete experiences shoulder dislocation, it is important for them to be assessed rapidly, according to a presenter here.
“We have to identify the injury and the direction of the dislocation, and, if the shoulder dislocated during activity, we want to try to reduce it where we are. You are not going to have a chance to get them to the ER if they are on the slopes,” Eric McCarty, MD, professor and chief of sports medicine in shoulder surgery at University of Colorado School of Medicine, said in his presentation at the International Extreme

PHILADELPHIA — Environmental exposures increase risk for cardiometabolic disease, but improved predictive tools combining satellite imaging, AI and time-variable considerations for risk could guide future interventions, a speaker reported.
Sanjay Rajagopalan, MD, MBA, FACC, FAHA, chief of cardiovascular medicine and chief academic and scientific officer at University Hospitals, Harrington Heart & Vascular Institute, discussed environmental exposures that impact cardiometabolic health and how future predictive models could account for factors such as built environment and changes in risk

CHICAGO — An AI model using electronic health record data helped researchers narrow down who should be screened for primary aldosteronism, according to a poster presented at ENDO 2026.
“With primary aldosteronism, the information and treatments we need already exist — the challenge has been putting them into practice,” Frank Lee, MD, trainee at Mayo Clinic in Rochester, Minnesota, told Healio. “With millions of adults at risk, we wanted to build an automated solution that is both widely accessible and broadly applicable.”
Some patients with difficult-to-control hypertension have primary

Overdose deaths in the United States fell 24.4% from 2023 to 2024, primarily due to decreases in deaths due to illegal fentanyl, according to a study published in Addiction.
But even though these declines were seen across all racial and ethnic groups, disparities persist, according to Joseph R. Friedman, MD, PhD, MPH, a resident in the department of psychiatry at the University of California, San Diego, and colleagues.
“Recently, early data showed a sudden an historic drop in U.S. overdose deaths between 2023 and 2024,” Friedman told Healio. “We wanted to dig into these numbers to see exactly

PHILADELPHIA — Medications that reduce blood pressure and improve glycemia may preserve kidney function over time despite initial eGFR dips, according to a speaker at the Heart in Diabetes CME Conference.
Matthew R. Weir, MD, professor and chief in the division of nephrology at University of Maryland School of Medicine, said eGFR dips “should be expected and planned upon” when using BP-lowering medications and should not deter clinicians from using them.
“An eGFR dip is cause of concern when it is more than 30%,” Weir told Healio. “But you have to carefully

Monica Wagner, PhD, RN, discusses her research presented at this year’s ONS Congress on how living in different socioeconomic regions may cause biological changes among patients with oropharyngeal squamous cell carcinoma.
Wagner, assistant professor at Frances Payne Bolton School of Nursing and member of the Population and Cancer Prevention Program at Case Comprehensive Cancer Center, and colleagues compared patients from disadvantaged and non-disadvantaged regions to better understand outcomes. They found that each area yielded different biological effects that can correspond to the

A pillar of lifestyle medicine is “food as medicine.” This is a health-focused behavioral approach encouraging patients to follow a whole food, minimally processed and predominantly plant-based pattern.
This supports the concept of food serving as a means of preventing, treating and reversing noncommunicable diseases.
A minimally processed diet tends to have higher nutrient content and lower calorie content. In contrast, a diet comprised of mostly industrially processed or ultraprocessed foods tends to have a higher calorie content and lower nutrient content due to emulsifiers, artificial

Editor’s Note: In Healio Allergy/Asthma’s column, “Food Allergy: Fact vs. Fiction,” Douglas H. Jones, MD, breaks down what’s true and what’s myth for a variety of topics related to food allergies. If you have a question that you would like answered in this column, email Jones at rmaaimd@gmail.com or Richard Gawel at rgawel@healio.com.
Few areas of medicine are more vulnerable to misinformation than nutrition.
Patients today are exposed to an endless stream of social media advice, elimination diets, “detox” protocols, supplement regimens and unvalidated food sensitivity testing, often delivered