Patients with early Alzheimer’s disease treated with diranersen experienced slower cognitive decline and greater reductions in tau compared with placebo, according to data presented at the Alzheimer’s Association International Conference.
Diranersen (BIIB080, Biogen) is an investigational antisense oligonucleotide therapy that reduces tau production by targeting microtubule-associated protein tau mRNA, including intracellular and extracellular tau, unlike other therapies that only reduce extracellular tau, Biogen said in a press release.
“Addressing intracellular tau is particularly important

Despite increasing awareness about the connection between oral health and chronic health conditions, awareness among patients and access to dental care remains limited, according to experts who spoke with Healio | Nephrology News & Issues.
“Lots of people don’t think of the oral cavity as part of their health care,” Andrea Lewis, LMSW, a quality improvement specialist at Quality Insights ESRD Networks, told Healio | Nephrology News & Issues. “Even the way insurance is broken down, you have vision, dental and medical insurance separated when they really shouldn’t be. They are all part

Men prescribed testosterone therapy despite no symptoms of hypogonadism have higher risk for major adverse cardiovascular events and all-cause mortality than men with hypogonadism using testosterone therapy, researchers reported.
In an analysis of data from the TriNetX global collaborative network published in eBioMedicine, researchers found risks for several CV events with testosterone therapy varied based on each person’s medical profile at initiation. Hatim Kerniss, MD, physician and researcher at University Hospital Frankfurt in Germany, said the findings shed light on the importance of

The University of Texas MD Anderson Cancer Center has retained its distinction as the No. 1 cancer hospital in the nation.
UT MD Anderson tops U.S. News & World Report’s 2026-2027 Best Hospitals rankings for cancer care.
This is the 12th straight year — and the 22nd time in 25 years — that UT MD Anderson has ranked first. The institution has finished first or second in cancer care every year since the publication began issuing its rankings in 1990.
“This ranking is a tremendous honor, and it reflects our unwavering commitment to continue making progress in our mission to end cancer,” Peter

U.S. News & World Report released its 2026-2027 Best Hospitals rankings Tuesday.
This year’s edition features 505 hospitals across 49 states and Washington, D.C. “that have demonstrated superior patient outcomes for a variety of common procedures and conditions,” according to a press release.
“U.S. News’ performance-driven metrics ensure American families can confidently find and choose high-quality care, often right in their own communities,” Ben Harder, U.S. News’ chief of health analysis and managing editor, said in the release.
Harder added that this edition also includes four new

SEATTLE — A new MRI-based classification system presented at the American Orthopaedic Society for Sports Medicine Annual Meeting provides “almost perfect” reliability for predicting the anatomical location of Achilles tendon ruptures.
“Achilles tendon ruptures are not uniform. They occur in distinct anatomical locations that may affect a patient’s treatment algorithm,” Robert E. Bilodeau, a third-year medical student at the University of Pittsburgh, told Healio. “The nice thing about this study is that we show we can reliably classify them using MRI and that patient-specific characteristics

Patients with recurrent respiratory tract infections receiving Broncho-Vaxom, a bacterial lysate-based therapy, had lower rates of infection at 12 months after vs. before treatment, according to preliminary results.
These data on Broncho-Vaxom (OM-85, OM Pharma) were presented at the 2026 European Academy of Allergy and Clinical Immunology Annual Congress.
“The REACH study delivers real-world evidence demonstrating that OM-85 initiation is associated with a reduction in respiratory tract infections (RTIs) in routine clinical practice,” David Price, FRCGP, chair of the REACH study committee and

U.S. News & World Report has again named Johns Hopkins the best hospital for rheumatology in the United States.
The publication’s 2026 to 2027 edition of its Best Hospitals rankings once again included Cleveland Clinic, Hospital for Special Surgery-New York Presbyterian University Hospital of Columbia and Cornell, the Mayo Clinic and Brigham and Women’s Hospital in the top five facilities for rheumatology.
The rheumatology rankings were based on expert opinion through a survey, while other specialties factored in various performance data, according to a press release from U.S.

Lincoln County issued a swimming advisory after about 2,000 gallons of untreated wastewater leaked into a Lake Norman cove in Denver, North Carolina.

HHS Secretary Kennedy toured a Danville agriculture research center and a Chatham rehab facility, defending rural health funding amid Medicaid cuts.