Executive order increases access to psychedelics

President Donald J. Trump has signed an executive order to accelerate and expand access to psychedelic drugs for patients with treatment-resistant mental illness.
“Today, over 14 million American adults have a serious mental illness,” Trump wrote in the order.
According to the order, approximately 8 million of these adults are on a prescription medication for their illness. Trump specifically cited the rate of more than 6,000 suicides per year among veterans, which has persisted for more than 20 years.
“Despite massive federal investment into researching potential advancements in mental health

Estrogen may mediate clotting risk linked to elevated Lp(a)

Elevated lipoprotein(a) was associated with increased risk for dangerous blood clotting among premenopausal women and postmenopausal women taking menopausal hormone therapy, according to a UK Biobank study.
Circulating estrogen levels may contribute to the prothrombotic effects of Lp(a), increasing risk for venous thromboembolism among women with already elevated Lp(a), according to data presented at the American College of Cardiology Scientific Session and simultaneously published in the European Heart Journal.
“The hematology community hasn’t widely adopted Lp(a) as a clotting risk factor

Reverse, anatomic TSA had similar return to sport rates

NEW ORLEANS — Results presented here showed reverse and anatomic total shoulder arthroplasty had comparable return to sport and satisfaction rates as well as functional outcomes in patients aged 65 years or younger.
“There does not appear to be a significant difference in anatomic vs. reverse [total shoulder arthroplasty] with the ability to return to sport,” Samuel A. Taylor, MD, orthopedic surgeon at Hospital for Special Surgery, told Healio about results presented at the American Academy of Orthopaedic Surgeons Annual Meeting.
Taylor, along with Anthony Finocchiaro, BS, and

Measles and the rheumatologist: A complex and growing concern

We live in complex times.
Who could have imagined only a handful of years ago, before COVID-19, that vaccines would become the subject of vitriolic debate in a country that has historically led the world in immunization programs and public health advances?
To be clear, scientific discussion about vaccine safety, efficacy and evolving technologies has always been appropriate. Ongoing safety monitoring remains essential not only for patient protection but also to maintain public trust.
However, legitimate academic debate should not obscure the clinical realities we now face with the reemergence of

Lower step count, higher screen time ups obesity risk for teens

Children who walk fewer steps per day and report longer amounts of screen time at age 11 to 12 years are more likely to develop overweight or obesity at age 13 to 14 years, according to findings published in Obesity.
“Clinically, our findings support a twofold approach to adolescent obesity prevention,” Jason M. Nagata, MD, MSc, associate professor in the division of adolescent and young adult medicine, department of pediatrics at University of California, San Francisco, told Healio. “Clinicians should assess both physical activity and recreational screen time during visits. Lifestyle

Acute care early in cancer trials predicts worse prognosis

Unanticipated use of acute care soon after starting a clinical trial may predict mortality risk among older adults with metastatic cancer, according to study results.
An analysis of data from several randomized trials showed participants who had at least one unplanned inpatient day within 2 months of trial registration exhibited a 25% higher risk for death than those who had no unplanned hospitalizations.
“That threshold — just one inpatient day in the first 2 months — is very low, and we were surprised to see it associated with mortality in such a significant manner,” lead author Arjun Gupta,

VIDEO: In-office keratectomies for common lesions may help avoid unnecessary surgery

MIAMI — In this video, Nandini Venkateswaran, MD, discusses her presentation from Sunshine Eye & Retina on performing in-office keratectomies for corneal lesions.
According to Venkateswaran, many corneal “lumps and bumps” may be able to be treated without the patient having to go to the operating room. Common lesions that can be addressed with keratectomy include Salzmann’s nodules, anterior basement membrane dystrophy and band keratopathy.
“I encourage all corneal specialists out there to really think about those corneal lumps and bumps and seek to optimize the corneal surface with

Pediatric e-cigarette exposure rises over recent years

From 2016 to 2023, reported pediatric exposures to traditional tobacco have dropped while exposures to e-cigarettes have risen, according to findings published in JAMA Network Open.
“Clinicians should ask specifically about e-cigarette use in the home and counsel caregivers on safe storage and minimizing access — not only within their own household, but also when others visit or when children are in different environments,” Perry E. Rosen, who conducted this research at the New Jersey Poison Control Center before becoming a DO/MS candidate at New York Institute of Technology College of

Early-life residential greenness, atopic dermatitis risk linked

Japanese children with high vs. low exposure to residential greenness in the first 6 months of life had a reduced risk for atopic dermatitis up to age 5 years, according to results published in Pediatric Allergy and Immunology.
“These findings highlight the potential importance of early-life residential greenness in the prevention of AD,” Ami Uematsu, MHS, of Tohoku University Graduate School of Medicine in Japan, and colleagues wrote.
Using data from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study, Uematsu and colleagues assessed 14,932 Japanese children to

SGLT-2 inhibitors reduced hepatic decompensation in cirrhosis

Use of sodium-glucose cotransporter-2 inhibitors was linked to significantly reduced risk for adverse kidney, cardiovascular and hepatic outcomes in patients with type 2 diabetes and cirrhosis, according to a study conducted in Taiwan.
“These protective associations were consistent across the full spectrum of cirrhosis causes, including viral hepatitis, alcoholic liver disease and nonalcoholic steatohepatitis, and remained robust after multivariate adjustment,” Mu-Chi Chung, MD, of Taichung Veterans General Hospital, and colleagues wrote.
“These findings extend the established cardiorenal