Two-month-olds with fevers who appear otherwise healthy are at a low risk for invasive bacterial infections and bacterial meningitis, according to an analysis of dozens of studies that included more than 34,000 infants.
Infants’ risk for bacterial infections is highest in the first few months of life, but most guidelines only address fever management for infants up to age 60 days, Brett S. Burstein, MDCM, PhD, MPH, a pediatric emergency medicine clinician-scientist at Montreal Children’s Hospital, and colleagues wrote in JAMA Pediatrics. Burstein and colleagues wanted to find out what the risk

A 76-year-old man presented with a 3-week history of binocular vertical diplopia.
He denied change in vision, pain with eye movements, headache, scalp tenderness, jaw claudication, constitutional symptoms, dysarthria, extremity numbness or tingling, facial droop, and prior similar episodes.
Ocular history was notable for dry age-related macular degeneration in the right eye, neovascular AMD in the left eye and cataract extraction bilaterally. He had previously received intravitreal anti-VEGF injections at an outside institution but had been lost to follow-up for several years. Medical history

Coadministration of COVID-19 and influenza vaccines on the same day was not associated with an increased risk for adverse events, according to data in Annals of Internal Medicine.
The study specifically looked at newer formulations of COVID-19 vaccines.
“Most of what we know about COVID vaccine safety comes from the early pandemic. But the vaccines are updated every year, and most people now have some immunity from past infection and prior vaccination,” Ziyad Al-Aly, MD, FASN, a senior clinical epidemiologist at Washington University in St. Louis, told Healio. “The old data may not reflect the

Finerenone was associated with early and sustained reductions in systolic blood pressure among patients with heart failure with moderately reduced or preserved ejection fraction, researchers reported.
The CV benefits of finerenone (Kerendia, Bayer), a nonsteroidal selective mineralocorticoid receptor antagonist, among patients with HF with moderately reduced EF (HFmrEF) or HFpEF were consistent, independent of BP reduction achieved, and treatment was safe regardless of baseline BP, according to a post hoc analysis of the FINEARTS-HF trial published in JAMA Cardiology.
“Hypertension is

CHICAGO — In a small cohort of patients with Cushing’s disease, most had their urinary free cortisol normalized after being administered asedebart, researchers reported at ENDO 2026.
“In Cushing’s disease ... you have a number of hormones that are affected,” Johan Luthman, DDS, PhD, executive vice president and head of research & development at H. Lundbeck, the developer of asedebart, and an author of the study, told Healio. “Cortisol is a main biomarker for that. So you can actually translate a very diverse set of symptoms into a core biomarker that relates to all the effects you’d like

Click here to read the Healio Exclusive, “Explore surgical options for gluteus tendon tears.”
Most gluteal tendon tears can be addressed endoscopically. It is the large, retracted tears that are the trickier ones.
If you want to use every technical skill that you can muster, even the bigger tears can be addressed endoscopically but there is a point where there are diminishing returns. As we look at the complication rate of open repairs vs. endoscopic repairs, the rate is about the same. There are probably a couple of studies that say the complication rate is a little higher with an open repair

ORLANDO — After hospital discharge, ICU survivors assigned to a 6-week, remote rehabilitation program did not have significant improvements in health-related quality of life at 8 weeks vs. standard care, according to data presented here.
In addition to being presented at the American Thoracic Society International Conference, this study was simultaneously published in JAMA.
“A structured, remotely delivered multicomponent rehabilitation intervention did not significantly improve health-related quality of life at 8 weeks,” Brenda O’Neill, PhD, lead for the Centre for Health and Rehabilitation

The odds for asthma exacerbation and moderate to severe asthma in pediatric patients with asthma and allergy did not significantly differ based on cat exposure, according to findings published in Frontiers in Allergy.
“We show in a nationwide cohort of children in Sweden with asthma and allergies that children living with a cat had similar asthma severity, exacerbation, asthma control and lung function to children living without cats in the short term,” Resthie R. Putri, MD, PhD, postdoctoral fellow at Karolinska Institutet, said in a press release.
In a population-based cohort study using data

While extreme heat is known for a variety of complications from dehydration to heat stroke, patients with cancer may be a group particularly vulnerable to its impacts, according to a study published in Environmental Research: Climate.
Specifically, extreme heat may cause social withdrawal and maladaptive behaviors among patients with cancer, which can be especially troublesome for those with limited social support networks, Kilan C. Ashad-Bishop, PhD, of the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science and Sylvester Comprehensive Cancer Center, and

In a position statement published earlier this year, the American College of Clinical Pharmacy called for the total withdrawal of direct-to-consumer advertising for medications in the United States.
The paper, published in April in the Journal of the American College of Clinical Pharmacy, stated that although such advertisements may increase disease awareness and encourage patient engagement, data suggest their impact on public health is, on the whole, negative.
“The balance of evidence and expert opinion suggests that DTC advertising results in net harm by promoting misleading