Lebrikizumab aids atopic dermatitis with, without comorbidities

Among patients with moderate to severe atopic dermatitis, atopic comorbidities did not change the benefits seen with lebrikizumab, according to data published in Annals of Allergy, Asthma & Immunology.
“Clinician awareness of atopic comorbidities and the additional impact that these conditions have on patients with AD is critical for shared decision-making around AD treatments and patient-centered care overall,” Ellen R. Sher, MD, FACAAI, physician at Allergy Partners of New Jersey and clinical associate professor at Rutgers Robert Wood Johnson Medical School, and colleagues wrote.
In a

High disease-specific survival seen with selective radioactive iodine in thyroid cancer

Adults with differentiated thyroid cancer have a high 10-year disease-specific survival, even with radioactive iodine not administered to most with low- or intermediate-risk disease, according to findings published in Thyroid.
“Radioactive iodine therapy has a very significant role in metastatic differentiated thyroid cancer,” Kumar Alok Pathak, MD, PhD, MHM, FRCSC, professor of surgery in surgical oncology at University of Manitoba and CancerCare Manitoba in Canada, told Healio. “Complete resection of the disease is extremely important of good locoregional control and disease-specific

Lung cancer survivors at risk for non-lung secondary cancers

Survivors of non-small cell lung cancer are at risk for both second primary lung cancers as well as non-lung secondary malignancies years after definitive local therapy.
A retrospective evaluation of nearly 500 patients found almost a quarter developed second primary malignancies, including 8% with breast, prostate and other non-lung cancers. Many of these cancers were diagnosed more than 4 years after completion of treatment.
“Chest CT surveillance remains essential after curative-intent therapy for NSCLC, but survivorship care cannot be chest-only,” Matthew T. McMillan, MD, radiation

Set boundaries, expectations to prevent ‘mentorship malpractice’

LAS VEGAS — Effective mentorship can accelerate careers, but toxic mentoring behaviors can just as easily derail academic progress if left unchecked, Frank I. Scott, MD, MSCE, warned attendees at Crohn’s & Colitis Congress.
“We know that mentorship can positively influence career trajectories,” Scott, codirector of Crohn’s & Colitis Foundation’s IBD Qorus and associate professor of medicine in the division of gastroenterology and hepatology at University of Colorado Anschutz School of Medicine, said. “Studies have shown significant benefits in terms of publication rate, a greater

Varenicline lowers cannabis use in men with cannabis use disorder

Weekly cannabis use sessions dropped among men with cannabis use disorder receiving varenicline plus medical management vs. placebo for 12 weeks, according to results published in Addiction.
“Additional research is needed to confirm that varenicline reduces cannabis use in men and to determine if subsets of women may benefit from varenicline,” Aimee L. McRae-Clark, PharmD, professor in the department of psychiatry and behavioral sciences and the department of neuroscience at the Medical University of South Carolina and adjunct professor in the South Carolina College of Pharmacy, told Healio.
In

Top papers from Orthopaedic Trauma Association Annual Meeting

WAIKOLOA, Hawaii — At Orthopedics Today Hawaii, Clifford B. Jones, MD, FAAOS, FAOA, FACS, discussed the best papers presented at the Orthopaedic Trauma Association Annual Meeting.
The first paper, which received the award for best research components, included 106 patients with fracture-related infections who underwent indocyanine green-based dynamic contrast-enhanced fluorescence imaging to predict reinfection. Jones said researchers found an infection recurrence of 29%, with a revision rate of 4% in small low perfusion areas vs. 27% in large low perfusion areas.
“This is probably not for your

Cannabis-based products improve pain, sleep in fibromyalgia

Patients with fibromyalgia who used cannabis-based medicinal products demonstrated modest, medium-term improvements in pain, anxiety and sleep, according to data published in Clinical Rheumatology.
“It is estimated that 1 in 2 patients with fibromyalgia consume cannabis, and a cross-sectional study found that in this group, 82% experience an improvement in pain,” Madhur Varadpande, MBBS, of the Medical Cannabis Research Group and department of surgery and cancer at Imperial College London, and colleagues wrote. “However, there is a lack of consensus on the effectiveness of

New report projects 64% increase in dementia across Europe by 2050

Alzheimer Europe has launched the "The Prevalence of Dementia in Europe 2025" report, which provides updated prevalence figures for the number of people living with dementia both for Europe as a whole, as well as the countries within. The report builds upon Alzheimer Europe's previous work in the "Dementia in Europe Yearbook 2019."