Older women in good cognitive health with higher levels of plasma phosphorylated tau 217 had greater risks for mild cognitive impairment or dementia up to 25 years later, according to a study published by JAMA Network Open.
Healio spoke with Adrian Moll, RN, director of nursing at Flournoy Health Systems, about how p-tau217 may inform individualized treatment that may minimize these risks as well as planning for care should these diseases emerge.
Healio: Could you summarize the association between p-tau217 and risks for dementia among women?
Moll: We are starting to view p-tau217 as a promising

KANSAS CITY, Mo. — Value-based care models remain key targets to improve quality of care and reduce costs to patients, but poor visibility and transparency remain barriers to implementation, an Annual Dialysis Conference speaker said.
Leslie P. Wong, MD, MBA, FACP, FASN, system executive medical director of medicine at Rochester Regional Health, New York, said new therapeutics and focus on cardiovascular-kidney-metabolic (CKM) syndrome at the federal level are opportunities for value-based kidney care.
"Innovation by the early adopters makes the news while passives and laggards remain the

NEW ORLEANS — Among patients with obesity who underwent catheter ablation for atrial fibrillation, those who took GLP-1s had lower readmission and mortality than those who had bariatric surgery, new data show.
The study was published in JACC: Clinical Electrophysiology and presented at the American College of Cardiology Scientific Session.
“Atrial fibrillation is strongly linked to obesity, and weight reduction has been shown to improve rhythm control after catheter ablation,” Rutvij Patel, MD, internal medicine resident at Creighton University School of Medicine and incoming cardiology fellow

In this video, Hope S. Rugo, MD, discusses two debates during Miami Breast Cancer Conference that highlighted treatment and testing decisions in breast cancer care.
According to Rugo, director of the Women’s Cancers Program and chief of breast medical oncology at City of Hope, the conference featured various session formats, but the debates were an “exciting way to present data.”
One debate focused on whether patients with breast cancer should receive trastuzumab deruxtecan (Enhertu; AstraZeneca, Daiichi Sankyo) in the neoadjuvant or adjuvant setting, based on data from

Adults with mild to moderate obstructive sleep apnea partaking in steam-assisted respiratory muscle training for 12 weeks had improved sleep architecture, according to data published in Journal of Clinical Sleep Medicine.
However, apnea-hypopnea index (AHI) and 3% oxygen desaturation index (ODI3) did not significantly differ between baseline and week 12, according to researchers.
“At this stage, the data do not support steam-assisted respiratory muscle training as a replacement for established OSA therapies,” Usame Al-Rammahi, doctoral researcher of pulmonary disease and clinical allergology at

The odds for higher severity oral food challenge reactions did not significantly differ between patients on inhaled corticosteroids and patients on an inhaled corticosteroid/long-acting beta-agonist combination, according to study findings.
These data were published in Annals of Allergy, Asthma & Immunology.
“It is reasonable for allergists to consider continuing the LABA when they’re doing a food challenge in a patient with asthma that’s controlled on a combination inhaled steroid and LABA inhaler,” Bruce J. Lanser, MD, MPH, director of the pediatric food allergy program at National Jewish

A short walk around the block, a 30-minute bike ride, or an intense 1-hour lifting session at the gym each can benefit patients with breast cancer undergoing chemotherapy.
A meta-analysis of more than 20 clinical trials showed women randomly assigned to exercise interventions, whether aerobic, strength or a combination of both, during treatment had more than a 60% greater likelihood of reporting improved quality of life than those who received standard care alone.
“All forms of exercise were beneficial,” Tracy E. Crane, PhD, RDN, director of lifestyle medicine, prevention and digital health at

Adults with early-onset colorectal cancer living in all-urban areas appear less likely to receive treatment within 90 days compared with those in rural or mostly urban areas in the U.S., according to data published in JAMA Network Open.
The cross-sectional analysis by Meng-Han “Mina” Tsai, PhD, assistant professor of cancer epidemiology at Augusta University, and colleagues also showed treatment delays were more common among men vs. women and patients who were Asian or Pacific Islander, Black or Hispanic vs. white.
“Young adults diagnosed with CRC may face significant barriers to accessing

There were three turning points in my early training that led me to rheumatology.
The first was in medical school during didactic lectures in immunology. I was intrigued by the immune system and how it acts like the body’s army against external invaders, such as infectious agents, that don’t belong. In autoimmune and rheumatic disease conditions, the immune system starts to recognize itself as being foreign. It mounts an attack against itself.
If the attack targets the thyroid, you can develop multiple sclerosis, an autoimmune thyroid disease in the brain and nervous system.