VIDEO: Decellularized amniotic membrane an option for neurotrophic keratitis

MIAMI — In this video from Sunshine Eye & Retina, Neel R. Desai, MD, discusses access to treatment options for neurotrophic keratitis.
Patients may have trouble accessing Oxervate (cenegermin-bkbj, Dompé), but according to Desai, other treatments are available, including decellularized amniotic membrane.
“Many times, we will place a Biovance 3L membrane (DefEYE) on a patient with stage 1, stage 2 or even stage 3 [neurotrophic keratitis], and we’re finding that by the time Oxervate has been approved, they don’t need it anymore,” Desai, of the Eye Institute of

Roflumilast safe nonsteroidal option for infants with eczema

DENVER — Roflumilast cream 0.05% was well tolerated in infants with mild to moderate atopic dermatitis and rapidly reduced disease symptoms, according to late-breaking data presented at the American Academy of Dermatology Annual Meeting.
Roflumilast (Zoryve, Arcutis) cream 0.05%, approved for the treatment of mild to moderate AD in children aged 2 to 5 years, is a once-daily, next-generation phosphodiesterase-4 inhibitor that offers a nonsteroidal option for families.
“We don’t have many drugs, either topical corticosteroids or nonsteroids, approved for children under age 2,” Lawrence F.

GLP-1 use shows ‘far higher’ than expected risk for residual gastric content in endoscopy

Use of GLP-1s or glucose-dependent insulinotropic polypeptide agonists before upper endoscopy significantly increased the risk for residual gastric volume, according to data published in JAMA Internal Medicine.
This risk, however, may be curbed by consuming a clear liquid diet the day before the procedure, Tilak Shah, MD, MHS, FACG, FASGE, an interventional endoscopist and medical director of the Pancreas Center at Cleveland Clinic Weston Hospital, and colleagues wrote.
“In 2022, the American Society of Anesthesiologists issued a consensus statement that patients on GLP-1 agonists should hold a

Any fracture may raise subsequent fracture risk for older adults

The risk for subsequent fractures is similar for older adults, regardless of whether they had an initial major osteoporotic fracture or nonmajor osteoporotic fracture, researchers reported.
In findings published in Journal of Bone and Mineral Research, researchers found that sustaining a major or nonmajor osteoporotic fracture raises the risk for subsequent fractures and mortality.
“The key message is that all fractures matter — not just the traditionally defined major osteoporotic fractures,” Dima A. Alajlouni, MScMed, PhD, research officer at Garvan Institute of Medical Research and in the

Shared decision-making at end of life tough for many clinicians

During an episode of the first season of “Scrubs,” Dr. Perry Cox, played by John C. McGinley, boasted to a group of clinicians that every patient that had been in the ICU when he started his shift at midnight remained alive later that day.
“And I damn sure intend for them to still be breathing when I get the hell out of here tonight at midnight,” he said. “I think you understand what kind of opportunity we have in front of us.”
The plot likened Cox’s effort to attempting to throw a perfect game in baseball.
The fictional scenario frequently plays out in the real world, too, even when trying to

The term ‘alcoholic’ conjures outdated stereotypes about an illness that afflicts 28 million Americans, says expert

People just aren't drinking the way they used to. "As recently as the late 1990s or early 2000s, 85% or more of high school seniors said they drank in the past year. Now that number is down to about 42%," said Kathryn McHugh, a Harvard Medical School associate professor of psychology at McLean Hospital and the director of the McLean Hospital Stress, Anxiety, and Substance Abuse Laboratory. "Those are whopping changes in effectively less than a generation."

Beyond rating scales: AI brings natural language to depression screening, improving accuracy and user experience

For over a century, standardized rating scales have been the dominant method of psychological assessment, but they often limit how people express complex or nuanced mental states. A new study introduces an approach that combines large language models with traditional psychometric tools to screen for depression. The research is published in the journal JMIR Formative Research.

New study shows faster recovery with minimally invasive prostate cancer treatment

A recent randomized clinical trial has found that men with localized, intermediate-risk prostate cancer recovered faster and experienced less short-term impact on their daily lives when treated with MRI-guided, transurethral ultrasound ablation (TULSA) compared with robotic prostate surgery. The results of the CAPTAIN Trial were presented at the SIR 2026 Annual Scientific Meeting in Toronto. The work is published in the Journal of Vascular and Interventional Radiology.