PopHIVE is ‘democratizing the data’ in public health

Yale School of Public Health recently unveiled a platform that offers reliable, real-time, synthesized health data directly to the public, providing a more complete picture for health care providers and public health experts.
PopHIVE — Population Health Information and Visualization Exchange — is a free tool “designed to help people see and act on population health trends,” according to a press release.
Daniel Weinberger, PhD, a professor of epidemiology at Yale School of Public Health, told Healio that he and the other PopHIVE collaborators were “frustrated for a

FDA asks for removal of suicidal ideation risk from GLP-1 labels following investigation

Editor’s note: This is a developing news story. Please check back soon for updates.
The FDA is requesting that manufacturers of three GLP-1 receptor agonists remove information on risk for suicidal ideation and behavior from their labels following an investigation, the agency stated in a Jan. 13 announcement.
The FDA said the requested labeling changes are for liraglutide (Saxenda, Novo Nordisk), injectable semaglutide 2.4 mg (Wegovy, Novo Nordisk) and tirzepatide (Zepbound, Eli Lilly). When the medications were originally approved for obesity treatment by the FDA, each of their labels included

What FDA’s report on forever chemicals means for cosmetic products

The FDA recently announced that it found insufficient data to determine the safety of per- and polyfluoroalkyl substances, also known as forever chemicals, in cosmetic products, according to a press release from the agency.
“In accordance with our congressional mandate, the FDA today released its assessment of [per- and polyfluoroalkyl substances] (PFAS) in cosmetic products,” FDA Commissioner Marty Makary, MD, MPH, said in the release issued on Dec. 29. “Our scientists found that toxicological data for most PFAS are incomplete or unavailable, leaving significant uncertainty about consumer

Hypertensive pregnancy disorders vary by ethnicity

Risks for different forms of pregnancy-related hypertension varied among Asian American, Native Hawaiian and Pacific Islander populations, with Filipino individuals often experiencing highest risk, researchers reported.
Varying risk for hypertensive disorders of pregnancy after full adjustment suggests that structural and social factors may come into play in this population, according to a study published in the Journal of the American Heart Association.
“Asian American, Native Hawaiian and Pacific Islander individuals have historically been grouped into one racial/ethnic category for many

GLP-1s may lower risk for all-cause mortality, hospitalization in type 1 diabetes

Adults with type 1 diabetes who used a GLP-1 receptor agonist or other incretin-based drug had lower risk for all-cause mortality, hospitalization and other clinical health outcomes than those not using a GLP-1, according to study data.
Samita Garg, MD, associate professor of medicine at Cleveland Clinic Lerner College of Case Western Reserve University and of the department of gastroenterology, hepatology and nutrition of the Digestive Disease Institute at Cleveland Clinic Foundation, said the prevalence of overweight and obesity has been increasing among people with type 1 diabetes in recent

Cystatin C and creatinine eGFR differences impact kidney outcomes

Major differences between eGFR based on cystatin C compared with creatinine were associated with higher rates for all-cause mortality, CV events and kidney failure for outpatients, according to data published in JAMA.
Serum creatinine and cystatin C-based eGFR measurements are established as reliable markers for chronic kidney disease diagnosis and treatment, but each method of calculating eGFR is affected by different factors that can impact a patient’s prognosis, according to Josef Coresh, MD, PhD, director of the Optimal Aging Institute at NYU Langone Health, Morgan E. Grams, MD, PhD, the

Vestibular rehab may have positive effect on vestibular migraine

Vestibular rehabilitation was associated with an impact on dizziness in vestibular migraine, but more detailed research is needed to fully investigate its efficacy, results of a literature review and meta-analysis show.
“The current literature on the effect of vestibular rehabilitation in vestibular migraine is surprisingly limited, with fewer than a dozen studies overall and substantial heterogeneity in study design and outcome measures,” Jad El Ahdab, MD, postdoctoral research fellow at the Cleveland Clinic’s Neurological Institute, told Healio about the results published in Headache. “In

Neutropenic diet best during blood cancer treatment

A long-standing practice through which people hospitalized for blood cancer treatment are restricted to eating cooked foods appears justified, study results suggest.
Patients undergoing hematopoietic stem cell transplant or induction chemotherapy for acute leukemia demonstrated a lower risk for major infections with a neutropenic diet than a more liberalized diet, results of a randomized phase 3 noninferiority trial showed.
Greater adherence to the liberalized diet correlated with even higher risk for major infection. Meanwhile, nutritional benefits — including calorie or protein intake — did

Inhaling wood smoke negatively changes respiratory microbiome

Among healthy adults, inhaling wood smoke for 2 hours negatively impacted the lung microbiome by raising the amount of potentially harmful bacteria found 24 hours after exposure, according to a press release.
This study published in American Journal of Respiratory and Critical Care Medicine also found that lung macrophage cells, which the release highlighted as “important for clearing harmful exposures,” fell following controlled wood smoke exposure.
To learn more about these findings and how clinicians can use them to inform their patients about the dangers of wildfire smoke, Healio spoke with

In-home reintroduction protocol promising in alpha-gal syndrome

An in-home mammalian meat reintroduction protocol was feasible and safe among patients with alpha-gal syndrome who had declining alpha-gal IgE titers and avoided red meat, according to study results.
These data were published in The Journal of Allergy and Clinical Immunology: In Practice.
“Our reintroduction protocol gives clinicians a tool they can employ for select patients to allow them to liberalize their diet,” Maya R. Jerath, MD, PhD, FAAAAI, professor and associate chief of the division of allergy and immunology at Washington University in St. Louis, told Healio. “Publishing this