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Epioxa, an epithelium-on corneal cross-linking therapy for keratoconus, demonstrated positive outcomes in visual acuity, durability and safety at 3 years, according to a press release from Glaukos.
As Healio previously reported, the FDA approved Epioxa (riboflavin 5’-phosphate ophthalmic solution) in October 2025, making it the first epi-on cross-linking procedure in the U.S. The long-term phase 3 GLK-202-03 extension study followed 38 eyes of 35 patients who had received one treatment of the therapy, with no

The Nobel Prize in Physiology or Medicine has been awarded to three scientists involved with pioneering research into optogenetics, the study of how nerve cells shape feelings and behaviors in the living brain.
The scientists include Karl Deisseroth, PhD, MD, a physician-scientist with Stanford University and investigator with the Howard Hughes Medical Institute; Peter Hegemann, PhD, Hertie senior professor of neuroscience at Humboldt University in Berlin; and Georg Nagel, PhD, professor of molecular plant physiology at the University of Würzberg, Germany, according to a press release.

In a new position paper, ACP detailed key principles for ethical, responsible AI use in healthcare.
AI — when implemented thoughtfully — has the potential to strengthen clinical decision-making, advance patient care “and preserve the central role of the patient-physician relationship,” according to an ACP press release. However, the technology is being adopted rapidly and “there has not been consensus on guidance around issues” like disclosure, fairness and privacy, and both “physicians and patients need practical ethical guidance to help ensure these technologies are used responsibly,

Adults with type 2 diabetes who sleep 7 hours or more per night may have elevated risk for developing diabetic nephropathy, according to data published in the Journal of the Endocrine Society.
“Diabetic kidney disease is a major complication of diabetes and can eventually lead to kidney failure and an increased risk of cardiovascular disease,” Tomoya Mita, MD, PhD, assistant professor of endocrinology, diabetes and metabolism at Juntendo University Graduate School of Medicine in Tokyo, said in a press release. “Sleep is a simple and routinely experienced aspect of daily life, so our findings

Patients with bipolar I disorder experienced significant improvements in their acute manic symptoms after 3 days of lumateperone treatment, and these improvements continued for 3 weeks, according to a poster presented at Psych Congress 2026.
The safety profile was consistent with prior studies of treatment, Michael E. Thase, MD, chief of the division of mood and anxiety disorders treatment and research program at the University of Pennsylvania, and colleagues wrote.
“People with bipolar I disorder are generally treated with mood stabilizers, antipsychotics, or a combination of treatments,

With so many red light devices on the market, knowing which one to recommend and how to advise patients use it can be challenging.
In this Beneath the Surface video interview, Joel M. Gelfand, MD, MSCE, FAAD, the James J. Leyden Professor of Clinical Investigation and professor of dermatology and epidemiology at University of Pennsylvania’s Perelman School of Medicine and Healio Dermatology’s Chief Medical Editor, spoke with David M. Ozog, MD, FAAD, FACMS, chair of the department of dermatology at Michigan State University College of Human Medicine, about how to prescribe red light therapy.
An

Women with severe asthma who used tezepelumab experienced improvements in lung function at 6 months, according to a poster presented at the European Respiratory Society International Congress.
Although tezepelumab (Tezspire, AstraZeneca) has been approved for severe asthma, the evidence of its effectiveness in the real world remains limited, Stefan anjovi, MD, resident, Clinic for Pulmonology, University Clinical Center, Nis, Serbia, said during his presentation.
“Our aim was therefore to evaluate early changes in lung function and asthma control in patients treated with tezepelumab in

VIENNA — In the first 10 patients treated in a study, the Lynx pattern scanning laser system showed the ability to perform panretinal photocoagulation quickly, efficiently and with less pain.
“Lynx (Norlase) is the only laser indirect ophthalmoscope that can create patterns,” Nassim Abreu, MD, said during a booth presentation at the Euretina congress. “Before this laser, all pattern lasers were connected to a slit lamp,” whereas this laser is fully built into a lightweight headset that allows the user to move freely.
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Moving away from mirror-generated patterns, the

Kidney transplant and wait-listing rates were lower for beneficiaries with Medicare Advantage vs. traditional Medicare, according to study data published in JAMA.
The 21st Century Cures Act, passed in 2021, permitted all individuals with end-stage kidney disease to enroll in Medicare Advantage plans, according to Ankur Shah, MD, MPH, associate professor of medicine at the Warren Alpert Medical School of Brown University, and colleagues. However, data exploring whether Medicare insurance type impacts access to kidney transplant have been limited, the researchers wrote.
“Earlier work had shown

A real-world analysis of hematologic healthcare showed patients young and old are having virtual appointments, and a single patient-initiated communication within the portal can result in seven additional electronic messages.
Approximately 20% of adult hematology appointments at Mayo Clinic in Minnesota between 2023 and 2025 occurred virtually, with minimal differences based on age and residence.
Additionally, most clinicians reported spending at least 30 minutes per day dealing with in-basket messaging, but few billed for it.
“Digital healthcare delivery in hematology is now commonplace, and