A once-weekly injectable GLP-1/GIP dual agonist reduced HbA1c by up to 2.65 percentage points at 48 weeks and lowered body weight for adults with type 2 diabetes and overweight or obesity, according to topline data from a phase 2 trial.
As Healio previously reported, enicepatide (Roche), formerly known as CT-388, reduced body weight by up to 22.5% more than placebo at 48 weeks for adults with overweight or obesity in a phase 2 trial. In new findings from another phase 2 trial named CT-388-104, enicepatide was assessed over 48 weeks in adults with type 2 diabetes plus overweight or obesity. The

Red light therapy has exploded across social media as a trending wellness treatment, but what is the science behind it?
In this Beneath the Surface video interview, Joel M. Gelfand, MD, MSCE, FAAD, the James J. Leyden Professor of Clinical Investigation and professor of dermatology and epidemiology at University of Pennsylvania’s Perelman School of Medicine and Healio Dermatology’s Chief Medical Editor, spoke with David M. Ozog, MD, FAAD, FACMS, chair of the department of dermatology at Michigan State University College of Human Medicine, about the mechanisms and history behind red light

MUNICH — Statin initiation after a diagnosis of type 2 diabetes was associated with lower absolute and relative risk for all-cause dementia compared with no statin initiation, a speaker reported.
The effect was most pronounced in patients who initiated statin therapy within 1 year of their type 2 diabetes diagnosis, according to the researchers.
Addressing traditional CV risk factors could also prevent development of dementia among people with diabetes, according to data presented at the European Society of Cardiology Congress and simultaneously published in The Lancet Regional Health –

Chronic kidney disease screening rates have increased since 2016, but diagnosis rates remain low at earlier disease stages, according to an analysis from the National Kidney Foundation and Manatt Health Strategies.
In a nationwide claims analysis, researchers reviewed millions of Medicare fee-for-service and Medicare Advantage claims between 2016 and 2023 to understand trends in guideline-concordant CKD screening and diagnosis rates.
Results showed that screening rates in which beneficiaries received both eGFR and urine albumin-to-creatinine (UACR) testing increased from 17% to 20% for

People with type 1 diabetes may not have increased risk for hypoglycemia after sexual intercourse, according to data that will be presented at the European Association for the Study of Diabetes annual meeting.
In findings from a small study of 12 adults with type 1 diabetes who wore a continuous glucose monitor, researchers did not see a rise in level 1 or level 2 hypoglycemia events in the 2 hours after sexual activity compared with 2 hours before. Dominika Orłowska, MD, of the department of diabetology and internal medicine at Medical University of Warsaw in Poland, said the findings are

While the prevalence of cigarette smoking is falling, use of alternative nicotine products, such as e-cigarettes, is rising over recent years, according to posters presented at the European Respiratory Society International Congress.
“For clinicians, the key message is that asking only whether someone smokes cigarettes is no longer enough,” Charmaine Helk-Lim, PhD, senior researcher at Ludwig Boltzmann Institute for Lung Health and author on one poster, told Healio.
“We need to routinely ask about vaping, heated tobacco, nicotine pouches and other products too — particularly in adolescents and

In adults with severe uncontrolled asthma, elevated nocturnal cough rates were linked to increased odds for worse asthma symptoms up to 3 days after, according to data presented at the European Respiratory Society International Congress.
“Passive monitoring could complement the information [clinicians] already receive from patients and from intermittent clinical assessments,” Fleur L. Meulmeester, MSc, PhD candidate at Leiden University Medical Center, told Healio. “Our study is not large or generalizable enough to say that it can guide treatment decisions yet, but it suggests that objective

Regulatory limits on water contaminants found in public drinking water may not be strict enough to protect individuals from developing cancer.
An analysis of more than 50,000 women from California showed those exposed to the highest government-approved levels of trihalomethanes in community water systems had significantly greater risk for uterine cancer overall and specifically endometrioid tumors.
Additionally, women in the highest tertile of haloacetic acids exposure had significantly elevated risk for nonendometrioid tumors.
“Are current limits protective against this cancer? That’s a fair

Patients with inflammatory bowel disease who used marijuana reported symptom relief, improved daily functioning and reduced opioid analgesic use, survey results showed.
Prior research indicates some patients with IBD use marijuana to manage disease symptoms or treatment-related adverse events.
“Marijuana use is prevalent for symptom control among patients with IBD and is rising with legalization; however, it is often not discussed in clinic visits,” Naueen A. Chaudhry, MD, assistant professor of gastroenterology at University of Florida, told Healio. “Physicians managing IBD do not have

A 25-year-old with Vogt-Koyanagi-Harada disease grew fine hairs on normally hairless thumb skin, a finding her doctors say is undocumented.