Resistance to the main drug in front-line malaria treatments is becoming more widespread across East Africa, according to new research by Imperial College London. The study, published in The Lancet Infectious Diseases, maps the rise in artemisinin resistance in the region and suggests one of the safeguards built into these treatments is being eroded. The researchers warn that their findings raise the risk that the effectiveness of current treatments could decline over time if resistance continues to spread.

A feature News and Perspectives story on technological advances in oncology was published in Journal of Medical Internet Research. Authored by JMIR Correspondent Benedette Cuffari, "AI-Designed Radiopharmaceuticals: How Machine Learning Is Redefining Precision Cancer Therapy" reports on the integration of deep learning and generative AI in radiopharmaceutical medicine, its impact on accelerating drug design, and how personalized dosimetry can improve patient outcomes.

To develop new and better peptides, the short amino acid strings behind medicines like GLP-1 drugs, researchers have used AI to generate candidates and to predict their properties.

Phase 3 clinical trial results (TRANSCEND-T2D-1) published in The Lancet report that retatrutide, an investigational once-weekly injection for diabetes management, can significantly improve blood sugar levels and lead to substantial weight loss in people with Type 2 diabetes. The study included adults with Type 2 diabetes who were not taking diabetes medicines and whose blood sugar was not adequately controlled with diet and exercise alone.

A team of researchers from VCU Massey Comprehensive Cancer Center, the VCU School of Dentistry and the University of Pennsylvania recently published a study in Nature Communications examining why some oral inflammatory diseases progress much more rapidly than others.

While exploring the world around them, both humans and other animals continuously interpret information they pick up with their sight, hearing, touch and other senses. Neuroscience research suggests that the brain does not individually process every single sensory experience, but rather organizes information into mental models known as internal representations.

A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of patients whose first scan was negative, according to new research published in the July issue of The Journal of Nuclear Medicine. Findings from the repeat PSMA scans, which included both local and distant disease, resulted in a change in management for nearly 50% of these patients.

Information processing using living organisms is an important area of biotechnology that has already been explored in previous studies.

A new study led by UC San Francisco has found an alarming rise in invasive breast cancer among Asian American women over the last two decades.

Scores of people in the United States have been sickened by a parasite commonly linked to contaminated fresh produce that can cause weeks of watery diarrhea. But there are ways to protect yourself and still enjoy summer's bounty of fruits and vegetables.