Gaze patterns vary substantially among people with varying levels of vision, pointing to the need for individualized rehabilitation strategies and assistive technologies, according to a study.
“Research has shown that participants with low vision often direct gaze downward or toward nearby surfaces, while fully sighted individuals maintain a more forward-looking focus,” Junchi Feng, a doctoral student at NYU Tandon School of Engineering, and colleagues wrote in Disability and Rehabilitation: Assistive Technology. “Other work has reported narrower scanning ranges or altered

The combination of belzutifan plus lenvatinib significantly improved outcomes for patients with clear cell renal cell carcinoma who progressed following immunotherapy compared with cabozantinib monotherapy.
Data from the randomized phase 3 LITESPARK-011 trial, presented at ASCO Genitourinary Cancers Symposium, showed belzutifan (Welireg, Merck) plus lenvatinib (Lenvima, Eisai) improved PFS 30% and had nearly twice the durability of cabozantinib.
“I find these data very exciting,” Robert J. Motzer, MD, genitourinary medical oncologist at Memorial Sloan Kettering Cancer Center, said during a

The FDA has granted orphan drug designation to orziloben for the treatment of intestinal failure-associated liver disease, according to a press release from the manufacturer.
Orziloben (NorthSea Therapeutics), previously known as NST-6179, received the same designation from the European Medicines Agency’s Committee for Orphan Medicinal Products. This approval builds on the rare pediatric disease designation awarded to orziloben in 2023.
“[Intestinal failure-associated liver disease (IFALD)] is a devastating liver disease for patients with chronic intestinal failure and can progress to end-stage

NEW ORLEANS — Although formal opt-out rates from Medicare are low among orthopedic surgeons, a presenter here said patterns exist across subspecialty, region and practice type.
“This could be because of administrative burden and declining inflation-adjusted reimbursement rates that contribute to that decision to opt out,” Catherine B. Hurley, MS, a second year medical student at the Florida State University College of Medicine and member of the research team in the Spine Lab in the department of orthopedics at Brown University, said in her presentation at the American Academy

PHILADELPHIA — Among adults with hereditary angioedema, the safety of navenibart up to 24 months was favorable, according to interim trial data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
Hereditary angioedema (HAE) attack rates also fell with this novel investigational long-acting monoclonal antibody inhibitor of plasma kallikrein, according to the interim results.
“If you’re a clinician who is not seeing patients with HAE, these data, I think, are valuable to understand YTE modification,” Adil Adatia, MD, assistant professor at the University of

Three-quarters of kidney transplants in the U.S. come from deceased donors, and donation after circulatory death, in contrast to brain death, now accounts for 45% of all deceased kidney donor transplants, according to study data.
In addition to kidney donations, rates of donation after circulatory death rose during the past 25 years for livers, hearts, lungs and pancreases, Macey L. Levan, JD, PhD, associate professor of surgery and population health at NYU Grossman School of Medicine and director of the Center for Surgical and Transplant Applied Research Qualitative Core at NYU Langone

ECG screening can assist in the detection of potentially life-threatening cardiac conditions, but legislation mandating preparticipation screening for young athletes may do more harm than good, according to an expert panel.
Florida recently passed legislation mandating universal ECG screening for all competitive athletes, including high school students, a move opposed by the American College of Cardiology in a recent report.
Jonathan H. Kim, MD, MSc, FACC, professor of medicine, founding director of Emory Sports Cardiology, chair of the ACC Sports and Exercise Cardiology Council and chair of

For many young ophthalmologists, the backbone of daily clinical practice is formed by cataract surgery.
Surgeons strive to improve patient outcomes, enhance the patient experience and make their practices stand apart. All three goals can be met by integrating select oculoplastic procedures into the full cataract surgery experience.
When patients present for cataract evaluation, they often have coexisting lid issues that impact both visual function and aesthetics. Patients with dermatochalasis, ptosis and brow ptosis can have a decreased superior visual field. Unaddressed, these conditions can

MIAMI BEACH, Fla. — Devices used in combination with medical therapy can improve treatment of acne lesions and even help patients see quicker results, according to a speaker at South Beach Symposium.
Acne is commonly seen in dermatology offices, and patients often report dissatisfaction with their treatment regimen, Michael H. Gold, MD, a dermatologic surgeon and founder and medical director of Gold Skin Care Center and Tennessee Clinical Research Center in Nashville, said during the presentation. Acne lesions are often associated with stigma, depression and even social phobia, Gold said.
“What

High-dose oral insulin did not reduce risk for progression to type 1 diabetes among children with stage 1 disease, according to data from a phase 2 trial published in Diabetes Care.
In the Fr1da Insulin Intervention trial conducted in Germany, 220 children aged 2 to 12 years with stage 1 type 1 diabetes were randomly assigned to once-daily oral insulin (Eli Lilly) or placebo for 1 year (50.9% girls; median age, 4.8 years). Children were considered to have stage 1 type 1 diabetes if they tested positive for more than one type 1 diabetes autoantibody and had normal glucose levels at baseline.