Few molecules in medicine generate as much excitement — and as much noise — as peptides.
Walk into any medical spa, open any luxury skin care brand’s website or scroll through a longevity-focused biohacking forum and you will find peptides promised as the solution to wrinkles, muscle loss, metabolic dysfunction and aging itself. What you will find far less frequently is a rigorous accounting of what the evidence actually supports.
As a dermatologist-scientist, I am constantly asked about peptides — by patients shopping for serums, by colleagues curious about injectables and increasingly by

The excitement and high-energy atmosphere of the FIFA World Cup may increase risk for cardiovascular events, so fans — especially those with known cardiovascular disease — should take precautions to minimize their risk.
“Soccer is a worldwide phenomenon, and heart disease is also a worldwide phenomenon,” Sunil Rao, MD, director of interventional cardiology at NYU Langone Health, told Healio. “There’s a lot of national pride and a lot of excitement about these matches, and blood pressure can go up and down as you’re watching ... as the teams get closer to a goal, celebrations after a goal.

Amniotic membrane has been in clinical use in ophthalmology for more than half a century. The histological nature of the membrane has been used for various eye surface diseases, and indications have expanded.
Amniotic membrane (AM) is the innermost layer of the placenta and consists of a thick basement membrane and an avascular stromal matrix. Since its first ophthalmic use in the 1940s and its reintroduction by Tseng and colleagues in the 1990s, amniotic membrane transplantation (AMT) has become an important tool in ocular surface reconstruction.
AM is composed of five layers: epithelial

Only one out of every five adults with cirrhosis in safety-net health systems receive guideline-concordant hepatocellular carcinoma surveillance.
Rates have dropped significantly since before the COVID pandemic, according to data published in JAMA Network Open, and researchers have not observed a rebound after.
“Even when you look at the period before the pandemic, what we describe as baseline, liver cancer screening was already dismally low,” Robert J. Wong, MD, MS, clinical associate professor of medicine in the division of gastroenterology and hepatology at Stanford University School of

Adults with major depressive disorder experienced statistically significant and clinically meaningful improvements with a single dose of lysergide through 12 weeks, according to a press release from Definium Therapeutics.
“Major depressive disorder and generalized anxiety disorder impose an enormous burden on patients, families and our society,” Robert Barrow, CEO of Definium Therapeutics, said during a webcast regarding the study. “And despite decades of research, the need for transformative new therapies remains.”
Part A of the phase 3 randomized, double-blind Emerge study included 149 adults

PHILADELPHIA — Most websites selling GLP-1 receptor agonists prescribe medications without any direct interaction with a health care professional, according to data from a “secret shopper” study.
Researchers attempted to obtain GLP-1 prescriptions from 49 websites selling the class of medication from August to December 2025. A researcher created a simulated patient profile designed to meet eligibility for a GLP-1 prescription. The researcher received a prescription from 45 of the 49 websites, despite 26.5% of websites requiring a video visit and 6.1% requiring a phone call. Findings from the

Recent data reveal a striking paradox: While 73% of endocrinologists prescribe glucose-lowering medications, fewer than 10% of nephrologists do.
This difference highlights a critical opportunity. Historically, nephrologists have deferred metabolic management to primary care or endocrinology, but the interconnected reality of cardiovascular-kidney-metabolic (CKM) syndrome requires a more holistic approach.
And because patients with advanced kidney disease see their nephrologist more frequently than their primary care physician or other specialists, nephrologists are uniquely positioned to close

The orthopedic workforce shortage is no longer a distant projection. It is an emerging access problem, a practice management challenge and a test to organize our specialty before the gap becomes irreversible.
For decades, workforce forecasts have alternated between warnings of surplus and projections of shortages. However, that uncertainty has now narrowed. Recent analyses using the Health Workforce Simulation Model from the Bureau of Health Workforce point in the same direction. Demand is rising, the supply is tightening and the mismatch between the two will hit rural communities, the South

Secukinumab was superior to placebo in exhibiting sustained remission at 52 weeks in patients with relapsed polymyalgia rheumatica, according to findings published in the New England Journal of Medicine.
“Polymyalgia rheumatica is a common inflammatory disease characterized by pain and stiffness in the shoulders and hips,” John H. Stone, MD, of the division of rheumatology, inflammation and immunology at Massachusetts General Hospital, and colleagues wrote.
“Glucocorticoids are the first-line treatment, but relapses and glucocorticoid-related toxic effects are common, which

Healio has garnered six APEX awards, including one Grand Award, this year.
The APEX awards highlight outstanding achievement in graphic design, editorial content and overall communications excellence. Each year, over 1,000 submissions are selected for Awards of Excellence and Grand Awards.
“Our editorial, design, and marketing teams work tirelessly to serve the medical community,” Matthew Holland, chief operating officer of Healio, said in a press release. “The continued recognition from the APEX Awards is a testament to the hard work and dedication of these teams. Congratulations to all