Individuals who do not complete followup colonoscopy after a positive stool test could be at substantially higher risk for colorectal cancer, according to a study published in JAMA Network Open.
Conversely, those with a negative screening colonoscopy result after a positive fecal occult blood test (FOBT) appear to be at lower risk for CRC.
“Our results highlight the importance of motivating patients to complete followup colonoscopy after a positive FOBT,” Hanna Heyman, MD, of the department of clinical science and education at Karolinska Institute, told Healio. “The findings also raise

The FDA has approved a self-administered autoinjector form of anifrolumab for the treatment of systemic lupus erythematosus, according to press release from the manufacturer.
The anifrolumab (Saphnelo, AstraZeneca) autoinjector, dubbed the Saphnelo Pen, has been approved for once-weekly use alongside standard therapy. The drug, a type I interferon receptor antagonist, was first approved in IV form for SLE in 2021.
“The FDA approval of the anifrolumab autoinjector is a monumental step forward in lupus management, literally bringing transformative care right to the patient’s doorstep,”