Nearly 30% of adults with an elevated BMI in the U.S. and more than 97% of those with a high BMI in Japan did not receive a diagnosis for obesity, according to findings from the CALOR study published in Obesity.
Deborah B. Horn, DO, MPH, DABOM, MFOMA, medical director at the University of Texas Center for Obesity Medicine and Metabolic Performance and clinical assistant professor in the department of surgery at University of Texas McGovern Medical School in Houston, and colleagues wrote that the shift in recognizing obesity as a chronic disease makes it crucial to understand the prevalence of

Click here to read the At Issue to this Healio Exclusive.
Take a look at the Healio | OSN calendar page, and you will find more than three dozen meetings, symposia and summits that make up a year of ophthalmology gatherings.
Whether they are one-room, single-day conferences, such as Clinical Trials at the Summit, or they take up full convention centers, such as the American Academy of Ophthalmology annual meeting, they all give physicians a chance to stand in front of their peers to present research, discuss hot topics and celebrate their profession.
Speaking at these conferences is a shared

MUNICH — Adults with atrial fibrillation participating in a yearlong high-intensity exercise program spent nearly 50% less time in AF and were less likely to be hospitalized for any cause compared with usual care, researchers reported.
“Exercise is now part of the guideline recommendations, but it is still underused,” Bjarne Martens Nes, PhD, a researcher with the Cardiac Exercise Research Group at Norwegian University of Science and Technology, said during a press conference at the European Society of Cardiology Congress. “We also know that many patients and doctors remain unsure of whether

MUNICH — In patients with severe hypertriglyceridemia, plozasiran was well-tolerated, reduced triglycerides by up to 81% and prevented acute pancreatitis events compared with placebo, a speaker reported.
“Severe hypertriglyceridemia is probably one of the largest gaps in the management of lipid disorders. Above 5 mmol/L is a gateway for all sorts of conditions that preventative cardiologists [and] diabetologists have difficulty accessing and treating because the treatments are not very effective,” Gerald F. Watts, DSc, MD, PhD, FRCP, FRACP, FCSANZ, Winthrop Professor of Cardiometabolic

Among individuals using liraglutide, semaglutide, tirzepatide or naltrexone-bupropion, the risk for respiratory adverse events did not differ from placebo, according to findings published in Annals of the American Thoracic Society.
For weight-loss medication use in individuals with asthma, this systematic review and meta-analysis only identified one study.
“The available evidence does not suggest an increased risk of common respiratory adverse events with several widely used weight-loss medications, particularly GLP-1 and dual GLP-1/GIP receptor agonists,” Ian J. Saldanha, MBBS, MPH, PhD,

Healthcare providers, parents and caregivers have two new reviews to look to for a clearer understanding on barriers to epinephrine use in infants and toddlers and how to recognize and treat anaphylaxis, according to a press release.
One review, published in Pediatric Drugs, is catered to pediatricians and discusses the underuse of epinephrine for anaphylaxis in infants and toddlers and how to overcome barriers to use.
The other paper, published in Expert Review of Clinical Immunology as a plain language review, is designed for parents, caregivers, primary care clinicians, and preschool and

A 42-year-old stopped speaking and ate almost nothing. Every scan came back normal, and her silence turned out to be entirely deliberate.

A cocker spaniel with brain inflammation circled compulsively for years. A behavior referral and fluoxetine did what immune drugs could not.

A 50-year-old woman's left hand kept undoing her right hand's work while she got dressed. A stroke in the corpus callosum explained it.

BioNTech terminated a Phase 2 mRNA cancer vaccine trial in colorectal cancer after monitors found a survival imbalance between the two arms.