Q&A: Common pesticide linked to early-onset colorectal cancer

A global, commonly used pesticide could be associated with the rising incidence of early-onset colorectal cancer.
A pair of analyses identified picloram, which the EPA described as “a systemic herbicide used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, rangelands, pastures and small grain crops,” as a potential new risk factor for the disease.
“We didn’t have any clue,” José A. Seoane, PhD, head of the cancer computational biology group at Vall d’Hebron Institute of Oncology in Spain, told Healio.
Researchers found smoking, diet and educational

Dual-target CAR-T drug shows remission in systemic sclerosis

A dual-target CD19/BCMA chimeric antigen receptor T-cell therapy yielded “profound, sustained” remission in 11 patients with refractory systemic sclerosis, according to data presented at the EULAR 2026 Congress.
“As we all know, despite advances in immunosuppressive, biologic and antifibrotic therapies, a subset of patients with refractory, progressive systemic sclerosis continues to experience uncontrolled skin fibrosis, lung involvement and functional decline,” Yajing Zhang, MD, PhD, of Beijing GoBroad Boren Hospital, in China, told attendees at the meeting. “CD19