Teen cannabis use in Northern California increased following the legalization of adult recreational cannabis and later declined during the COVID-19 pandemic, according to new research from Kaiser Permanente published in JAMA Network Open.

An international research team with the participation of researchers from the University Medical Center Göttingen (UMG), Germany, has developed a mouse model that offers new insights into the development of a rare but serious muscle disease. The researchers were able to demonstrate that the persistent inflammation in inclusion body myositis is linked to impaired cellular "garbage disposal"—an important clue for new treatment strategies. The findings have been published in the journal Brain.

The larynx, also known as the voice box, is home to the vocal folds and is the reason people can talk and sing while manipulating pitch and volume. The vocal folds are covered with mucosa, or mucous membranes.

Smoking is really bad for you. Most people know that. Even smokers think smoking is bad for one's health. But most people don't know just how bad it is. More people in the United States die every year from smoking than from alcohol, illegal drug use, car accidents, suicides, and murders combined.

This Clinical Chemistry and Laboratory Medicine review examines a central challenge in precision medicine: whether medical laboratories should prioritize metrologically sound, proteoform-resolving protein quantification by mass spectrometry or adopt scalable, affinity-based proteome profiling platforms built for high-throughput discovery and machine learning. It concludes that while emerging proteomics technologies expand diagnostic possibilities, careful validation, standardization, and quality assurance will be essential, with a hybrid path likely offering the most practical way forward.

A nationwide analysis of provider-verified NIS-Child data from 2010 to 2023 found that US childhood vaccination coverage remained generally high but was consistently shaped by social and structural factors such as maternal education, income, insurance, language, and region. The study also showed that coverage of the combined seven-vaccine series rose over time, yet persistent disparities remained, especially for vaccines such as influenza, hepatitis A, and rotavirus.

Researchers analyzing 2.46 million ambulance dispatches across 13 Chinese cities found that humidity can intensify the health risks linked to both hot and cold temperatures, with cold-dry and warm-wet conditions posing the greatest risks. Future climate projections suggest compound temperature-humidity events will become more frequent and increasingly shift health burdens toward heat-related events in China.

A qualitative study of 30 UK adults found that many people see ultra-processed foods as unhealthy but struggle to define them clearly or distinguish them from other processed foods. The findings suggest that clearer communication and food-environment changes, not education alone, may be needed to help people reduce UPF intake.

A Cell Perspective argues that generative AI models could help tackle cancer’s multiscale, multimodal complexity by complementing the Hallmarks of Cancer framework. It proposes that models capable of complex pattern recognition, multimodal fusion, and contextual reasoning could improve cancer detection, biological discovery, and precision oncology, while still requiring rigorous validation and human oversight.

Air pollution is associated with increased migraine activity, according to a study published on April 15, 2026, in Neurology, the medical journal of the American Academy of Neurology.