PHOENIX — Approximately half of U.S. patients with heart failure also have elevated cardiovascular inflammation risk despite guideline-directed medical therapy, regardless of their ejection fraction, a speaker reported.
Elevated CV inflammation risk was tied to obesity, diabetes, kidney disease, advanced HF and increased levels of interleukin-6 and N-terminal pro-B-type natriuretic peptide biomarkers, according to a new subanalysis of the POSEIDON registry presented at the Heart Failure Society of America Annual Scientific Meeting.
“Heart failure affects a large number of patients.

PHILADELPHIA — Adults with type 1 diabetes who discontinued semaglutide had a greater drop in time in range and worse glycemic variability than those who never used the drug, according to data from an ADJUST-T1D extension study.
As Healio previously reported, the ADJUST-T1D trial found adults with type 1 diabetes who received semaglutide (Ozempic, Novo Nordisk) for 26 weeks had greater improvements in multiple continuous glucose monitoring metrics and a larger decrease in HbA1c than those receiving placebo. New data from a post hoc extension study presented at the Breakthrough T1D Clinical and

NASHVILLE, Tenn. — Tezepelumab significantly improved histologic remission and dysphagia symptoms at 24 and 52 weeks compared with placebo among individuals with eosinophilic esophagitis, according to a presenter.
Thymic stromal lymphopoietin (TSLP), an antibody, is associated with EoE pathogenesis.
“Food allergens and environmental factors interact with the epithelium of the esophagus and release alarmins, of which TSLP is one,” Evan S. Dellon, MD, MPH, FACG, director of the Center for Esophageal Diseases and Swallowing at University of North Carolina at Chapel Hill, told attendees at ACG

SAN DIEGO — Patients with severe symptoms of long COVID experienced relief with 12 weeks of Bezisterim therapy, according to a poster presented at the 151st Annual Meeting of the American Neurological Association.
Bezisterim has the potential to be the first drug approved for long COVID, and further studies would be appropriate, Penelope Markham, PhD, senior vice president of liver disease and long COVID programs at BioVie Inc., and colleagues wrote.
“This is actually the first study to show any efficacy in long COVID,” Markham told Healio. “There have been huge efforts to test repurposed

A Chicago woman is charged after a nearly 2-year-old died from fentanyl and medetomidine, a vet sedative. What families should know about overdose risks.

Johnson County declared the norovirus outbreak at Bentwood Elementary in Overland Park over after 97 illnesses and warned the real count is likely higher.

Wedgewood Pharmacy recalled compounded veterinary drugs shipped since February that may be too weak or too strong. How owners and clinics can check lots.

A 28-year-old with lung cancer had one yellow eye but normal liver tests. Scans showed his cancer had spread to the back of that eye.

Seven years after placement, calcium coated a 9-year-old's brain shunt, and fluid built up again. Surgeons left the old tube in and added a new one.

An 18-year-old with fluid squeezing his heart also had a pituitary mass that looked like a tumor. Thyroid treatment shrank it to normal in six months.