ORLANDO — Patients with obstructive sleep apnea and obesity who had strong- vs. moderate-response endotype characteristics had more improvement in obstructive sleep apnea severity with tirzepatide, according to data presented here.
These findings were presented at the American Thoracic Society International Conference.
“We are excited about these findings because they offer the chance to now be able to share with patients: ‘You have the characteristics that place you in a group of patients who respond remarkably to tirzepatide weight loss therapy.’ Or, by contrast, ‘You have characteristics

A home-based electronic symptom monitoring system previously shown to reduce ED visits and improve quality of life among people with metastatic cancer also may help reduce health disparities, study results suggest.
Historically underserved groups — including Black individuals and those with lower educational attainment — derived particular benefit from the intervention, an exploratory analysis of the randomized PRO-TECT trial showed.
Researchers also observed pronounced improvement among younger patients — who frequently experience higher levels of distress — as well as women, shown in prior

Young athletes with knee injuries demonstrated similar adiposity gains vs. uninjured athletes at 2 years post-injury, revealing a potential window for obesity prevention strategies, according to a study in Arthritis Care & Research.
“Knee joint injuries and elevated adiposity are independent risk factors for knee osteoarthritis (OA),” Justin M. Losciale, DPT, PhD, of the George E. Wahlen Department of Veterans Affairs Medical Center in Salt Lake City, and colleagues wrote. “Evidence also indicates that youth and young adults who experience a knee injury have higher body