RAAS inhibitors show benefits in pediatric CKD vs. CCBs

Renin-angiotensin-aldosterone system inhibitors were linked to better pediatric chronic kidney disease outcomes compared with calcium channel blockers, according to study data published in JAMA Pediatrics.
Renin-angiotensin-aldosterone system (RAAS) inhibitors and calcium channel blockers (CCBs) are two primary antihypertensive treatments used in the pediatric population, according to Michelle R. Denburg, MD, MSCE, associate professor of pediatrics (nephrology) at the Children’s Hospital of Philadelphia, and colleagues. However, few trials have compared the effectiveness of both

Symptom progression slowed in Lewy body dementia with zervimesine

Adults with mild to moderate dementia with Lewy bodies had slowed decline in four clinical signals with the oral, brain-penetrant, small module therapeutic zervimesine vs. placebo at 6 months, according to phase 2 trial findings.
These data on zervimesine (CT1812, Cognition Therapeutics) were presented at the 2026 Alzheimer’s & Parkinson’s Diseases Conference in Denmark.
“Dementia with Lewy bodies is an understudied, underserved, misunderstood and largely unrecognized public health crisis with no approved treatments, leading to high disease burden and significant daily challenges for

Hepatitis vaccine uptake declining, liver disease could increase

Amid policy shifts and a rise in misinformation fueling vaccine hesitancy, fewer infants in the U.S. are receiving the hepatitis B virus birth dose.
Earlier this year, the CDC changed its universal recommendation for HBV birth dose to include only infants with known risk factors, a move temporarily halted by a federal court order in March 2026. Similar changes were made to the CDC’s hepatitis A vaccine recommendation.
The American Academy of Pediatrics opposed the change, issuing its own vaccine schedule that maintains the universal recommendation for HBV and HAV vaccination.
The American

Machine learning may aid in ILD diagnosis

Researchers successfully used machine learning on lung ultrasound images to detect interstitial lung disease in patients with systemic sclerosis and idiopathic inflammatory myopathy, according to data published in Arthritis Care & Research.
“Beyond its accuracy, [lung ultrasound (LUS)] offers advantages such as low cost, accessibility, no radiation, and sustainability,” Robert M. Fairchild, MD, PhD, clinical chief of the division of immunology and rheumatology at Stanford University, and colleagues wrote. “However, operator dependence and variability in acquiring and

How the brain recovers from noise-induced damage

When a sound stops, our auditory system generates a precise "offset" response that marks this moment. This enables the brain to measure the duration of a sound and detect brief gaps in communication signals, such as in conversations. Researchers at LMU have now discovered how the brain is able to preserve this crucial aspect of hearing—the ability to detect when a sound ends—when it has previously been exposed to damaging noise levels.

GLP-1 drugs have long-term benefit for heart health, review suggests

New research has shown that GLP‑1 weight-loss drugs deliver protection against heart attacks, strokes, and premature death over a sustained period of time. Researchers from Anglia Ruskin University (ARU) analyzed data from more than 90,000 patients enrolled in large-scale international studies and found that people given glucagon-like peptide‑1 (GLP‑1) receptor agonists were significantly less likely to suffer major cardiovascular events than those given a placebo.