COVID-19 infection linked to increased mask-wearing due to silent risk awareness

Researchers at The University of Osaka have found that individuals in Japan who have been infected with COVID-19 are more likely to wear masks than those who have not. In a four-year-long study, they discovered this change is not driven by fear, but by a heightened perception of the risk of "silent infection," the idea that one could be infected and spread the virus without knowing. This insight could reshape public health messaging for future pandemics. The study, "The impact of COVID-19 infection experience on risk perception and preventive behaviour: a cohort study," was published in Epidemiology & Infection.

A fish that grows old in months reveals how kidneys age—and how a common drug protects them

In a new study published in Kidney International, researchers report that drugs known as SGLT2 inhibitors prevented age-related deterioration of kidney structure and function in the African turquoise killifish, a vertebrate that completes its entire lifespan in just a few months. The findings reveal specific biological mechanisms that may help explain why these drugs consistently protect kidney and cardiovascular health in people, beyond their original role in lowering blood sugar.

Immunotherapy before surgery boosts survival for for liver cancer patients, clinical research finds

Immune checkpoint inhibitor (ICI) therapy before surgery for hepatocellular carcinoma (HCC) may produce major pathological response in about one-third of the surgical patients. The clinical and pre-clinical research highlighted that the formation of organized immune hubs within the tumor (tertiary lymphoid structure) after ICI therapy is critical for the induction of antitumor immunity.

Influence of environmental exposures in heart failure previously underestimated, say researchers

Whether heart failure develops and how it progresses depends not only on physical factors, but also on external influences and the duration of exposure, according to scientists at University Medical Center Mainz in collaboration with an international research group. Their systematic review, published in Nature Reviews Cardiology, revealed that both individual risk factors, such as high blood pressure and lack of exercise, and stressful environmental factors, such as poor air quality, noise, and heat, are important starting points for preventing the disease and more effectively reducing the number of people affected.

Menopause linked to loss of gray matter in the brain, poorer mental health and sleep disturbance

Menopause is linked to reductions in gray matter volume in key brain regions as well as increased levels of anxiety and depression and difficulties with sleep, according to new research from the University of Cambridge. The study, published in Psychological Medicine, found that hormone replacement therapy (HRT) does not appear to mitigate these effects, though it can slow the decline in reaction times.

Medicaid tries new approach with sickle cell: Companies only get paid if costly gene therapies work

Serenity Cole enjoyed Christmas last month relaxing with her family near her St. Louis home, making crafts and visiting friends. It was a contrast to how Cole, 18, spent part of the 2024 holiday season. She was in the hospital—a frequent occurrence with sickle cell disease, a genetic condition that damages oxygen-carrying red blood cells and for years caused debilitating pain in her arms and legs. Flare-ups would often force her to cancel plans or miss school.