Dupilumab boosts esophageal distensibility, diameter for EoE

CHICAGO — Dupilumab significantly improved esophageal distensibility and diameter in eosinophilic esophagitis at 24 weeks, alongside marked gains in endoscopic and histologic disease outcomes, data presented at Digestive Disease Week showed.
“Esophageal strictures and narrowing, also called fibrostenosis, are commonly seen in EoE, and traditionally are treated with esophageal dilation,” Evan S. Dellon, MD, MPH, director of the Center for Esophageal Diseases and Swallowing at University of North Carolina School of Medicine at Chapel Hill, told Healio. “However, some clinical data suggested that

Eroding ACA enrollment portends higher insurance rates

Enrollment in the Affordable Care Act continues to erode as some customers struggle to make premium payments, with the declining numbers churning market uncertainty for insurers. In response, insurers are likely to raise rates again next year, following this year's larger-than-typical hikes.

Self-reported family history underestimates heart attacks among close relatives

A new study from Karolinska Institutet shows that people's own reports of heart attacks in the family only partially correspond with register data. The findings suggest that heart attacks among relatives are often underreported, particularly for events occurring early in life. The results, published in European Journal of Epidemiology, show that the agreement between self-reported data and register data was only moderate.

Study finds substandard bowel cancer care for people with learning disability

People with a learning disability are at higher risk of developing bowel cancer, yet face significant barriers at nearly every stage of the care pathway, University of Manchester and Christie NHS Foundation Trust have found. The population-based study of more than 2 million people showed individuals with an intellectual disability are more likely to develop bowel cancer, especially before the age of 50. The study is published in BMC Medicine.