The FDA accepted an investigational new drug application for the epinephrine intranasal powder OX640 for treating anaphylaxis, according to a press release from Orexo.
“Although epinephrine is well established as a treatment, significant challenges remain with today’s injection-based products,” Nikolaj Sørensen, MSc, president and CEO of Orexo, said in the release.
The limitations of current epinephrine autoinjectors per the release include fear of needles, use errors, and storage and shelf-life challenges. Data included in the investigational new drug application for OX640 (extensive

HUNTINGTON BEACH, Calif. — Vagus nerve stimulation with the SetPoint System offers a new and promising approach for patients with refractory rheumatoid arthritis, according a speaker at the Congress of Clinical Rheumatology West.
“Vagal nerve stimulation is a new option now proven for patients with RA,” Jeffrey Curtis, MD, MS, MPH, Marguerite Jones Harbert-Gene V. Ball endowed professor of medicine at the University of Alabama at Birmingham, told Healio. “It is the first new mechanism of action that we have had in RA in the last 14 years, since JAK inhibitors. Its excellent safety

The Dimora MegaSorb™ Silicone Foam Dressing range is built around a shared fluid-management platform but comes in three formats designed for different care scenarios: Square, Sacral, and Silver Silicone Foam Dressings. Understanding what they share — and where they differ — can make choosing between them more straightforward.

The FDA approved Fayuvi, the first gene therapy for Sanfilippo syndrome type A. What families should know about access, cost and safety checks.

A 60-year-old woman went under for gallbladder surgery with no airway complaints. Mask ventilation faltered, and a cyst was hiding her vocal cords.

A CT after an assault found a 35-year-old man's left kidney had crossed to the right side, fed by an artery branching off his iliac artery.

Ultrasound showed only gallstones. During surgery, two separate cystic ducts drained one gallbladder, an anomaly that imaging rarely catches.

A 69-year-old woman's latissimus dorsi muscle was missing on one side during breast reconstruction. A CT from two years earlier had already shown it.

A 45-year-old woman's spleen had migrated to her pelvis and was twisting, dragging her pancreatic tail with it and triggering recurrent pancreatitis.

Mississippi awarded more than $104 million in federal rural health grants across 167 projects. Where the money goes and why rural access matters.