Common arthritis drugs reduce systemic Sjögren’s disease activity in 24 weeks

A combination of two widely available anti-rheumatic drugs offers the first effective and affordable treatment for patients with Sjögren's disease with systemic disease activity, according to new results from a clinical trial coordinated by UMC Utrecht. The study showed that treatment with leflunomide and hydroxychloroquine reduced disease activity in patients with moderate-to-severe disease while maintaining a favorable safety profile.

Researchers discover way to inhibit brain cancer’s infiltration mechanism in glioblastoma

A team of experimental oncology researchers at the University of Alberta is shedding light on how the deadly brain cancer glioblastoma spreads. In newly published research, they identify a potential treatment target to slow or even stop it. Glioblastoma is an aggressive form of cancer that affects 4 in 100,000 people, according to Brain Tumor Canada, with an average survival of 12 to 18 months.

Clarifying the interplay between host and gut microbiota in selenium metabolism

Selenium (Se) is an essential trace mineral found in everyday dietary items, such as seafood, meat, and whole grains. Our bodies depend on it for many biological functions, from the synthesis of antioxidant enzymes to immune system regulation. However, Se is unusual among nutrients in that the quantity window between too little and too much is quite narrow. Se deficiency has been linked to weakened immunity, while excess intake can increase the risk of type 2 diabetes and cardiovascular disorders. This makes understanding how the body absorbs, processes, and eliminates Se especially important.

GLP-1-based meds are linked to fewer heart events in adults with obesity, autoimmune disease

Among adults with both obesity and an autoimmune disease, those taking a glucagon-like peptide-receptor 1 agonist (GLP-1RA) medication had lower rates of emergency department visits and were less likely to experience serious cardiac events, such as stroke, pulmonary embolism or death when compared to similar adults who were not taking these medications, according to new research published in the Journal of the American Heart Association. This research was presented at the American Diabetes Association 2026 Scientific Sessions in New Orleans.

Cohort makes data from more than 5,800 patients hospitalized with COVID-19 available to the scientific community

The Biostatistics Unit at the Germans Trias i Pujol Research Institute (IGTP), in collaboration with researchers from several Catalan health care and research institutions, has published the DIVINE study database in Scientific Data. The journal specializes in publishing datasets and promotes the accessibility, proper documentation and reusability of these resources by the scientific community.