Diabetes elevates risk for infection

NEW ORLEANS — People living with diabetes and prediabetes have a significantly greater risk for infection compared with people without diabetes, according to a presentation at the American Diabetes Association Scientific Sessions.
Patients with type 1 diabetes had the highest risk, followed by patients with type 2 diabetes and patients with prediabetes, according to the researchers.
“‘Classical’ complications of diabetes (micro- and macrovascular disease) are well understood, but chronic high blood sugar levels associated with diabetes raise the risk of range of health problems,” Julia

Bepirovirsen achieved functional cure in chronic HBV

Significantly more patients with chronic hepatitis B virus infection achieved functional cure at week 72 after treatment with bepirovirsen than placebo, according to study results.
Findings from the phase 3 B-Well 1 and B-Well 2 trials were simultaneously presented at EASL Congress and published in The New England Journal of Medicine.
An estimated 240 million people globally have chronic HBV, which results in more than a million deaths each year, according to study background.
The goal of treatment is functional cure, which is defined as HBV DNA levels below the lower limit of quantification

Pediatric uveitis linked to immune-related inflammatory disease

Pediatric patients with noninfectious uveitis demonstrate a nearly 7-fold increased risk for developing first-time immune-mediated inflammatory disease vs. the general population, according to data published in JAMA Network Open.
“Pediatric uveitis is frequently associated with immune-mediated inflammatory diseases (IMIDs); however, population-level estimates of IMID risk and immunosuppressant use are
limited, as existing evidence is largely derived from tertiary-center cohorts with substantial
referral bias,” Jay Jiyong Kwak, MD, from the Institute of Vision Research at Yonsei