Chemotherapy hair loss distress higher in young, Black women

Black women with breast cancer were more likely to experience distress from chemotherapy-induced hair loss at younger ages compared with older women, according to a pilot study published in the Journal of the American Academy of Dermatology.
“Chemotherapy-induced alopecia affects the majority of patients receiving chemotherapy and is consistently reported as one of the most distressing treatment-related side effects,” Ananya Eeraveni, BS, a medical student at the University of Chicago Pritzker School of Medicine, told Healio. “Much of the existing research has focused on white patients,

Pollution impacts COPD risk score, early-life lung function link

In infants with high air pollution exposure, a rise in COPD polygenic risk score was linked to a reduction in lung function from infancy to school age, according to data presented at the European Respiratory Society International Congress.
“The main practical impact [of this study] is reinforcing that early-life exposures, not just adult smoking, are a target for COPD prevention,” Carla Rebeca da Silva Sena, PhD, postdoctoral researcher at University Children’s Hospital Basel, told Healio. “This means modifiable exposures in infancy and the preschool years carry long-term consequences for lung

Higher atopy rates found in patients with congenital ichthyosis

The percentages of patients with allergic rhinitis, food allergy and allergic asthma were higher in those with congenital ichthyosis vs. the general population, according to data published in The Journal of Allergy and Clinical Immunology.
Studied congenital ichthyosis types included lamellar ichthyosis, epidermolytic ichthyosis, congenital ichthyosiform erythroderma (CIE), X-linked ichthyosis, Harlequin ichthyosis, ichthyosis with confetti, erythrokeratodermia variabilis et progressiva (EKVP) and ichthyosis follicularis, atrichia and photophobia (IFAP).
“We need to think about all of these

Clinical obesity prevalent in bariatric surgery candidates

New Lancet Diabetes and Endocrinology Commission criteria, which distinguish clinical obesity from preclinical obesity, may better inform patient selection and risk assessment for bariatric surgery than BMI, analysis showed.
Nearly 75% of surgical candidates met criteria for clinical obesity — defined as excess adiposity with obesity-related organ dysfunction — which was associated with greater preoperative disease burden and higher perioperative risk.
“Because this risk doesn’t track with BMI, I think having [a clinical obesity] assessment may inform and improve anesthetic management and

Speaker: CAR T-cell trial deaths add ‘sobriety’ to discussions with autoimmune patients

HUNTINGTON BEACH, Calif. — The deaths of three participants in trials of Novartis’ chimeric antigen receptor T-cell therapy for autoimmune disease will “add some sobriety” to discussions with patients, according to a speaker.
“We’re in the very early days of learning about this,” Philip J. Mease, MD, MACR, FRCP, director of the rheumatology clinical research division at Swedish Medical Center/Providence St. Joseph Health, in Seattle, told Healio in an interview. “But it will have an impact on the ongoing efforts to get these therapies tested and