Academics improve for students with earlier ADHD diagnoses

Children diagnosed with ADHD at a younger age had better academic outcomes including higher grade point average, higher education completion and lower dropout rates than those diagnosed as teenagers, according to data.
Targeted support may improve academic outcomes for children with later diagnoses, Lotta Volotinen, MSc, a doctoral researcher at the University of Helsinki, and colleagues wrote in JAMA Psychiatry.
“Having ADHD has been associated with many adverse outcomes, e.g., lower school performance and educational attainment. But studies have also observed that ADHD treatment may help,”

Kidney transplant odds up for children living with low eGFR longer

Pediatric patients who lived with a low eGFR longer without dialysis had better odds to receive a preemptive or living donor kidney transplant, according to study findings published in Pediatric Nephrology.
Compared with adults, who must have an eGFR less than 20 mL/min/1.73 m² to be wait-listed for a transplant, children with chronic kidney disease do not have a “kidney function cutoff” for wait-list candidacy, according to Sandra Amaral, MD, MHS, medical director of the pediatric transplant program at the Children’s Hospital of Philadelphia, and colleagues. Therefore, researchers are unsure

Geographic patterns, neighborhood factors in COPD acute care use

Across a county in Texas, geographic patterning of census tract-level rates of COPD-related ED visits and hospitalizations was observed, according to data published in Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.
Additionally, several neighborhood demographic, socioeconomic and built environment characteristics were linked to the rates of COPD-related ED visits and hospitalizations in this observational, ecological study.
Researchers evaluated census tract-level incidence rates of ED visits, hospitalizations and 30-day readmissions for acute exacerbations of COPD

Alternative medicine linked with worse survival in breast cancer

Women with breast cancer treated with complementary and alternative medicines have significantly worse survival than those receiving traditional therapies, likely due to underutilization of proven modalities.
An evaluation of more than 2 million women with breast cancer showed those who reported treatment with complementary and alternative medicines (CAM) alone had more than 3.5 times higher likelihood of death in 5 years than those treated with traditional options.
Patients treated both traditionally and with CAM also had significantly worse OS, and had significantly lower utilization of

Late-night eating, stress linked to constipation, diarrhea

CHICAGO —Late-night eating habits coupled with stress were associated with lower gut microbiome diversity and abnormal bowel function, according to a study presented at Digestive Disease Week.
“Stress triggers what is known as allostatic load, which is the cumulative physiological toll of chronic stress on the body,” Harika Dadigiri, MD, resident physician at New York Medical College at Saint Mary’s and Saint Clare’s Hospital, said in a media briefing held before the meeting.
Dadigiri and colleagues conducted a multicohort, observational study to evaluate whether a connection exists between

Taltz plus tirzepatide promising in psoriatic arthritis, obesity

Treatment with ixekizumab plus tirzepatide achieves greater disease control, physical function and weight loss vs. monotherapy in patients with psoriatic arthritis and obesity, according to data published in Arthritis & Rheumatology.
“Overweight or obesity is disproportionately prevalent in PsA compared with the general population, with estimates ranging from 72% to 82%,” Joseph F. Merola, MD, MMSc, of the University of Texas Southwestern Medical Center and O’Donnell School of Public Health, and colleagues wrote. “… Obesity promotes a chronic, low-grade inflammatory state through