An increasing number of Americans are living well beyond the average life expectancy. It presents new and complex challenges about how to care for a vulnerable, often ignored demographic that is aging largely on its own.

"Like father, like son? Can parenting styles break the intergenerational pattern of alcohol and drug use?" A group of Brazilian researchers analyzed data on the behavior of 4,280 adolescents and their guardians based on this question, arriving at two important conclusions.

About 170,000 people in England every year spend their final days in pain, distress or without vital support that should be available to everyone at the end of life. These are the findings of the first major study in more than a decade to estimate unmet palliative care needs among people at the end of life. The paper was led by researchers at King's College London and Hull York Medical School, University of Hull, with contributions from the University of Edinburgh and was published in the Journal of Health Services Research & Policy.

The Trump administration has unveiled a sweeping set of regulatory proposals that would substantially change health plan offerings on the Affordable Care Act marketplace next year, aiming, it says, to provide more choice and lower premiums. But it also proposes sharply raising some annual out-of-pocket costs—to more than $27,000 for one type of coverage—and could cause up to 2 million people to drop insurance.

Since arriving at Yale School of Medicine in 2019 as an internal medicine resident, Evangelos Oikonomou, MD, DPhil—now an assistant professor of medicine (cardiovascular medicine)—has focused his research on developing artificial intelligence (AI) applications that can interpret traditional, routine cardiac tests to better assist providers in diagnosing cardiovascular diseases.

Chemotherapy is one of the most common weapons in the cancer-treatment arsenal, but its side effects are well known. Hair loss. Nausea and vomiting. Mouth sores. Fatigue.

The psychedelic effects recreational users often seek from taking ketamine do not predict the therapeutic benefits for people being treated for alcohol use disorder. The popular theory, which says that ketamine may have its therapeutic benefits because it produces strong psychedelic effects, has been called into question by a new study from King's College London and the University of Exeter, published in Addiction. The study suggests the treatment response may be down to other effects of the drug.

Some athletes go to the gym. Some run long distances across vast terrains. Some even build their fitness using brine and seafoam. But many Olympic hopefuls, such as those competing in this year's Games, sometimes schlep to more than 10,000 feet, where just breathing can, to the underconditioned, feel like a workout.

A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized mechanism that shapes how immune cells are selected during an immune response.

Some people may experience the "winter blues"—feeling sad from short days, climbing into bed earlier and resenting waking up on dark mornings. That's different than seasonal affective disorder (SAD), a term used to describe a type of depression that follows a seasonal pattern.