Rates of new-onset type 1 and type 2 diabetes rising among youths

Incidence of both type 1 and type 2 diabetes increased among children and adolescents from 2002 to 2023, with type 2 diabetes rates rising at a more rapid pace, according to data from the Colorado Diabetes Registry.
In findings that will be presented at the European Association for the Study of Diabetes annual meeting, researchers examined cases of new-onset type 1 and type 2 diabetes among children and adolescents in Colorado from 2002 to 2023. Tessa L. Crume, PhD, MSPH, associate professor of epidemiology at the University of Colorado School of Public Health, said the use of the Colorado

Patients with lung malignancy have more airway microplastics

A larger proportion of adults with vs. without lung malignancy had microplastics detected in bronchoalveolar lavage samples, according to a poster presented at the European Respiratory Society International Congress.
“The immediate clinical message is one of restraint as much as action: This observational study does not justify testing patients for microplastics or changing cancer care,” Ilias E. Dimeas, MD, respiratory medicine physician and fellow at the University College Dublin School of Medicine and the University of Thessaly, told Healio.
“However, the environment our patients breathe is

FDA grants priority review to lonvo-z for hereditary angioedema

The FDA has accepted Intellia Therapeutics’ biologics license application for lonvoguran ziclumeran for treating hereditary angioedema and granted priority review, according to a press release.
Notably, lonvoguran ziclumeran (lonvo-z) is a one-time infusion and in vivo CRISPR-based therapy.
Per the FDA, Intellia Therapeutics noted that there are no plans for an advisory committee focused on the application for lonvo-z.
“An FDA approval of lonvo-z would change the [hereditary angioedema (HAE)] treatment paradigm by introducing a potential one-time treatment that eliminates the cumulative burdens

Nearly a quarter of adults treated for HCV lack follow-up testing

Approximately one in four adults with hepatitis C virus infection who initiated treatment with direct-acting antivirals did not undergo follow-up RNA testing, according to a research letter published in JAMA Network Open.
However, 90% of that unmonitored population had been prescribed at least 56 days of DAA therapy, potentially leaving cured individuals unaccounted for and highlighting a notable gap in HCV surveillance efforts.
“Measuring care outcomes is essential to monitoring progress toward hepatitis C elimination,” Hasan Symum, PhD, of the CDC’s division of viral hepatitis, and colleagues

‘Where is the tissue damage?’ Data suggest fibromyalgia a central nervous system disorder

Recent genetic evidence from more than 2.5 million individuals suggests that fibromyalgia is a central nervous system disorder, rather than an autoimmune or psychiatric disease, according to data published in Nature Medicine.
In that study, published in July, Daniel J. Clauw, MD, director of the Chronic Pain and Fatigue Research Center, and professor of anesthesiology, medicine and psychiatry at the University of Michigan, and colleagues conducted a multi-ancestry genome-wide association meta-analysis of 54,629 patients with fibromyalgia and 2,509,126 controls.
The researchers identified 26