Study: AI-based cartilage imaging predicts knee replacement

Fully automated, AI-based cartilage segmentation with MRI identified knees requiring replacement with the same degree of success as manual human analysis, according to published results.
“For cartilage morphometry to become a scalable and useful endpoint in clinical trials of
disease-modifying (structure-modifying) interventions, image analysis should ideally be
performed automatically and objectively, without human intervention,” Felix Eckstein, MD, from the center for anatomy and cell biology at Paracelsus Medical University in Salzburg, Austria, and colleagues wrote in Arthritis

Patients with bipolar disorder benefit from GLP-1s

In addition to offering diabetes management and weight loss benefits, a national cohort study published in Acta Psychiatrica Scandinavica showed that semaglutide may also decrease psychiatric outcomes among patients with bipolar disorder.
“Semaglutide may be beneficial in reducing relapse/hospitalization rate,” Mark Taylor, MD, MBBS, BSc (Hons), FRANZCP, FRCPsych, FRCPE, professor at the school of medicine and dentistry at Griffith University in Australia, told Healio. “GLP-1s don’t appear to [present] any worrying safety signals (eg, suicidality).”
Although diabetes, obesity and bipolar