Vaping, smoking negatively impact exercise capacity

In healthy young adults with normal spirometry, e-cigarette users and conventional cigarette smokers had similar poorer exercise capacity and vascular function vs. never vapers/smokers, according to findings published in ERJ Open Research.
“This work is the first of its kind to identify reduced vascular function, ventilation efficiency and exercise capacity in people who vape and never smoked,” Azmy Faisal, PhD, senior lecturer of cardiorespiratory physiology at Manchester Metropolitan University and principal investigator of the study, told Healio.
“The consequences of this finding are

New Anaphylm sublingual epinephrine data address FDA’s concerns

Multiple human factors improved following revision of the packaging design and instructions for use on Anaphylm sublingual epinephrine film, according to topline results.
As Healio previously reported, the FDA cited concerns about human factors in the use of Aquestive Therapeutics’ Anaphylm (dibutepinephrine) for anaphylaxis and other type 1 allergic reactions in its complete response letter to the company’s new drug application in late January.
“Following receipt of the FDA’s complete response letter in January 2026, we worked closely with the agency to better understand and address the human