Physical education can boost children’s health and education—let’s make it central to the curriculum

The benefits of physical activity for children are enormous. As researchers of physical education (PE)—and ex-PE teachers—we know evidence shows it can have a positive impact on mental and physical health, social relationships, emotional control and confidence, as well as on academic performance. Why not make movement the framework that the rest of the school day is built upon?

A 3D-printed delivery system enhances vaccine delivery via microneedle array patch

The COVID-19 pandemic highlighted an urgent need for efficient, durable, and widely accessible vaccines. This prompted several important innovations in vaccine technology, and researchers continue to explore new and creative ways to make effective vaccines rapidly available to the greatest number of people. Researchers from the Institute of Industrial Science, The University of Tokyo have used 3D-printing technology to improve the viral titer of microneedle array patches, resulting in effective immunogenicity and protection against infection in mice. Their study is published in Scientific Reports.

Synergizing global clinical trials data: GLP-1 receptor agonist safety and novel clinical applications

A research team led by the Department of Medicine, under the School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has synergized the impacts of worldwide clinical trial data through a series of meta-analyses on GLP‑1 receptor agonists, an emerging cardiometabolic drug, offering in-depth insights into its safety profile and novel therapeutic potential in treating cardiovascular diseases.

Can chemo-resistant cancer cells be resensitized?

Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged cancer cells into a state of uncontrolled transcriptional activity, thereby creating a novel form of cellular stress that can make even chemo-resistant tumors sensitive again to treatment.