Causes of exacerbations in patients on benralizumab for severe eosinophilic asthma are related to infection rather than eosinophilic inflammation, according to results published in The Lancet Respiratory Medicine.
“The most interesting finding was that eosinophils remained fully depleted during exacerbations in patients treated with benralizumab, not only in the blood but also within the airways,” Rekha Chaudhuri, MD, honorary professor in the school of Infection and Immunity at University of Glasgow, told Healio. “Instead, we observed evidence of airway infection, including increased

The gap in cancer mortality between Black and white individuals narrowed dramatically over the past 30 years, largely due to decreases in lung and prostate cancers among men, and colorectal and cervical cancers among women.
Overall, 98 fewer excess cancer deaths per 100,000 among Black men and 22 fewer among Black women occurred from 2019 to 2023 than they did from 1991 to 1995.
“Population-wide cancer-control efforts have taken us a considerable distance in reducing the Black-white cancer mortality gap,” Chenxi Jiang, MPH, epidemiologist and associate scientist in surveillance, prevention and

Higher levels of forever chemicals in newborn dried blood spots, cord blood and maternal serum during pregnancy were linked to elevated fecal calprotectin in early childhood, study results showed.
Children of mothers with inflammatory bowel disease also exhibited higher levels of per- and polyfluoroalkyl substances (PFAS) than those whose mothers did not have IBD.
“Pollutants are being implicated in inflammatory bowel disease risk,” Manasi Agrawal, MD, MS, director of environmental gastroenterology and associate professor at Icahn School of Medicine at Mount Sinai, told Healio.
“Early life,

Medicare will require hospitals to capture unique device identifiers for implants starting in 2027, addressing a longstanding recall notification gap.

A House Oversight Democrat wants Taylor Farms' records on White House contacts before its lettuce recall. The company denies wrongdoing.

Nebraska's Medicaid director says roughly 200 people lost coverage on August 1, the first terminations under new federal work requirements.

Aurora Therapeutics deprioritized its lead personalized gene-editing program and cut staff, exposing how hard it is to scale one-patient CRISPR therapies.

FDA will merge specialized field inspectors into a generalist pool and centralize administration on October 1. What inspectors check and how to look up a manufacturer.

HRSA will test paying 340B discounts as rebates instead of upfront price cuts starting January 2027. Manufacturers must apply by August 24.

California law allows patients in active treatment to continue seeing an out-of-network provider temporarily. Here is who qualifies and how to request it.