Expert consensus pushes to redefine, manage rare liver disease

A multinational, multidisciplinary group of experts has created a consensus document to guide diagnosis, staging and management of adults with alpha-1 antitrypsin deficiency-associated liver disease, as well as advance research efforts.
Paul Kwo, MD, FAASLD, director of hepatology and professor of medicine at Stanford University, was part of the panel that convened under the auspices of AGA in collaboration with American Association for the Study of Liver Diseases, European Association for the Study of the Liver and Alpha-1 Foundation. The document was published in Gastroenterology.
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T cells also activated by microbiome in stem cell transplantation

In this video, Albert C. Yeh, MD, provides an overview on the role of microbes on T-cell activation after hematopoietic stem cell transplantation.
Yeh presented these findings at Tandem Meetings | Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR.
“The paradigm of transplant has always been, it’s the donor-host genetics that matters the most for transplant because any difference in genetics is what drives these T cells to activate in the host and potentially damage the host,” Yeh, physician and research associate of translational science and therapeutics at

Study in Timor-Leste finds fish supply must be paired with public awareness to tackle malnutrition

Malnutrition is a critical developmental obstacle in Timor-Leste, with poor maternal health and nearly half of its children under five suffering from stunting from diets that are chronically low in nutrient-rich foods, including fish. A new study from Timor-Leste, published in PLOS One, shows that when it comes to improving intake of dietary nutrition, increased fish supply only works in tandem with public awareness and not alone.

Unmasking the real sugar threat to kids during heart month

While most parents know to limit candy, the true danger of sugar in a child's diet is often hidden in plain sight. A growing body of research reveals that excessive sugar consumption in childhood is linked to a frightening list of long-term health problems, including an increased risk for heart disease, as well as obesity and type 2 diabetes. Consistent, high sugar intake can lead to serious health consequences such as these conditions.